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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA

Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA

http://golshanilab.neurology.ucla.edu/

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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA | golshanilab.neurology.ucla.edu Reviews

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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA

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Support Our Work

http://golshanilab.neurology.ucla.edu/support-our-work

David Geffen School of Medicine, UCLA. You can help support our work directly. Your philanthropic support can help fund work cutting-edge research and help find better treatments for autism and epilepsy. Traditional granting agencies will not support “high-risk/ high-reward” research. It is often this type of research that results in breakthroughs, and your donations can help us do this work. If you would like to help, please enter your contact information below. With gratitude. The Golshani Lab.

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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA - Lab Members

http://golshanilab.neurology.ucla.edu/lab-members

David Geffen School of Medicine, UCLA. Department of Neurology, MD/PhD: UC Irvine School of Medicine. PhD. Advisor: Edward G. Jones. PhD: UC San Diego. Advisor: Dr. Stephan Anagnostaras. PhD University of Crete;. PhD Advisor: Dr. George Chalepakis. Previous Postdoctoral Advisor: Dr. David Anderson. Email: svrontou@mednet.ucla.edu. PhD University of Nottingham, Advisor: Markus Owen. Email: jtaxidis@ucla.edu. PhD graduated from UCLA, PhD mentor: Dr. Istvan Mody. PhD. Email: ben.s.huang@gmail.com.

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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA - Techniques

http://golshanilab.neurology.ucla.edu/techniques

David Geffen School of Medicine, UCLA. 1 Two-photon guided in-vivo patch clamp recordings from behaving animals. In-vivo two photon stack of the visual cortex of an awake somatostatin-cre X Ai9 mouse taken from the pial surface up to layer IV at 3 micron increments. In-vivo whole cell recording (cell in red) of a L2/3 cortical neuron labeled with the calcium indicator Oregon Green BAPTA (cells labeled in green.). 2 Mapping of visual cortical receptive fields.

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Lab News

http://golshanilab.neurology.ucla.edu/lab-news

David Geffen School of Medicine, UCLA. 1 September 2015: BRAIN Initiative Grant. To build and share a new generation of miniaturized microscopes funded! In collaboration with Alcino Silva, Baljit Khakh, Dejan Markovic). 2 September 2015: IDDRC Center Grant. Main Project (Co-PI with Shifali Jeste) funded! We will study cortical and hippocampal network activity in two models Dup15q syndrome. 3 April 21st, 2015: Ben Huang’s. Http:/ www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4001.html.

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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA - Publications

http://golshanilab.neurology.ucla.edu/publications

David Geffen School of Medicine, UCLA. Truong, H, and Jones, EG; Developmental expression of GABA(A) receptor subunit and GAD genes in mouse somatosensory barrel cortex. J Comp Neurol. 1997 Jun 30;383(2):199-219. 2 Warren RA, Golshani P. And Jones EG; GABA(B)-receptor-mediated inhibition in developing mouse ventral posterior thalamic nucleus. J Neurophysiol. 1997 Jul;78(1):550-3. 6 Liu X-B, S Bolea, Golshani P. Hutnick L, Schweizer F, and Fan G; Conditional Dnmt1 deletion in dorsal forebrain disrupts dev...

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The Golshani Lab has shown that as mice transition from resting to running, the membrane potential of visual cortical neurons becomes more depolarized and less variable, increasing the responsiveness of these neurons to visual stimulation.

http://www.iclm.ucla.edu/hot/GolshaniDream.html

IC Learning and Memory. ICLM YOUNG SCIENTIST LECTURES. ICLM YOUNG SCIENTIST LECTURES. Our level of vigilance fluctuates during wakefulness. We may daydream one minute and the next minute we may be intensely focused on a task. How different levels of arousal control the sensitivity of the cerebral cortex to sensory input is still not understood. By directly performing whole-cell intracellular recordings from visual cortical neurons, Pierre-Olivier Polack, postdoctoral fellow in the Golshani lab.

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Golshani Lab - Department of Neurology - David Geffen School of Medicine, UCLA

David Geffen School of Medicine, UCLA. Maximum projection of a visual cortex layer 2/3 pyramidal neuron filled with Alexa 594 during an in-vivo whole-cell recording. Image was obtained with a two-photon microscope. Department of Neurology at David Geffen School of Medicine UCLA. 2012 Golshani Lab Powered by: Los Angeles Internet Marketing.

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