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Glucose Phosphate Isomerase (GPI) deficiency. This is JC and Aisha and we were born with Glucose Phosphate Isomerase. GPI) deficiency. GPI deficiency causes a rare blood anemia (other rare red cell enzymopathies include TPI. Our site brings together all those who have GPI deficiency and those who know people with GPI deficiency. The site contains detailed description of known and past cases as well as past and active research. To learn more about GPI deficiency, please click here.
Current Known Cases
http://www.gpideficiency.org/Current_Known_Cases.html
Glucose Phosphate Isomerase (GPI) deficiency. The table is being populated as more cases are being discovered. Known Allergies (eggs, bananas). IUGR Intrauterine growth restriction. Conjugated hyperbilirubinemia with abnormal liver dysfunction at birth (now resolving). 4 weeks (Hb before transfusion: 9-10). 4 weeks (Hb before transfusion 9.5-10). Yes (Hb at birth: 5.4). Yes (Hb at birth: 5.6). 5th percentile for height and weight. 2nd percentile for height and weight. Potential cure for anemia.
Past Known Cases
http://www.gpideficiency.org/Past_Known_Cases.html
Glucose Phosphate Isomerase (GPI) deficiency. Amoxicillin-Induced Hemolytic Anemia in a Child with Glucose 6-Phosphate Isomerase Deficiency. Department of Experimental Medicine, Section of Pharmacology `Leonardo Donatelli,' Second University of Naples, Via Costantinopoli 16, 80138 Naples, Italy, fax 39 081 5667652,. Targeted Therapy for Inherited GPI Deficiency. Dr Karadimitris at the Department of Haematology, Imperial College London, Hammersmith Hospital, Du Cane Rd., London W12 0NN, United Kingdom.
Literature
http://www.gpideficiency.org/Literature.html
Glucose Phosphate Isomerase (GPI) deficiency. Q and A - - CASE STUDIES - - DIAGNOSIS - - THERAPY. Answers by Dr. Andy Zoeller. 1 Is it possible to make F6PI (since there is no enzyme to turn G6PI into F6PI) synthetically and then inject it into a patient? The isomerase, GPI converts G6P to F6P. I will look around about other tissues or organs. 2 Do we know what enzyme is missing and is it possible to make it synthetically? Even if you made it synthetically, it would not be useful. This is a good question.
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Glucose Phosphate Isomerase (GPI) deficiency. This is JC and Aisha and we were born with Glucose Phosphate Isomerase. GPI) deficiency. GPI deficiency causes a rare blood anemia (other rare red cell enzymopathies include TPI. Our site brings together all those who have GPI deficiency and those who know people with GPI deficiency. The site contains detailed description of known and past cases as well as past and active research. To learn more about GPI deficiency, please click here.
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