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1

DNA Therapeutics - Advantage - Greenpak Biotech Ltd

http://www.greenpakbiotech.com/dna_therapeutics_advantage.htm

Advantages of Using pGRF Plasmid in Swine Productiont. Effect of pGFR Plasmid on Weight Gain in Pigs. Effect of pGRF Plasmid on pGRF and IGF-1 Concentration1. Effect of pGRF Plasmid on Immune Cells. Advantages of Using pGRF Plasmid in Swine Production. Improved feed conversion efficiency (10 %). Shortened production cycle (10? Improved meat quality (more lean meat and less back fat). Reduced incidences of disease and mortality rate. Increased resistance to heatstroke. Enhanced cellular immune response.

2

Contract Manufacturing - Advantage - Greenpak Biotech Ltd

http://www.greenpakbiotech.com/contract_manufacturing_advantage.htm

Plasmid DNA as Biotherapeutics. Quality Control of Plasmid DNA. Plasmid DNA as Biotherapeutics. Safer alternative than viruses for gene therapy. Ease of administering by direct injection. Advantages over conventional vaccines:. Low immunogenicity, thus allowing a course of multiple treatments. Improved stability of the vaccine. Stimulation of both B & T cell responses. Absence of any infectious agents. Relative ease of large scale manufacture. Quality Control of Plasmid DNA. 169;2008 GreenPak Biotech Ltd.

3

DNA Therapeutics - Milestones - Greenpak Biotech Ltd

http://www.greenpakbiotech.com/dna_therapeutics_milestones.htm

Milestones for pGRF Plasmid DNA. Milestones for pGRF Plasmid DNA. Showed efficacy and safety in mice. Showed efficacy and safety on pigs. Permit issued by the Ministry of Agriculture (MOA) for Intermediate Trial in Guangdong and Sichuan Provinces (large scale trials). MOA permit for Environmental Release Phase of Field Testing. Patent US6486134 granted by the USPTO (photocopy). Successfully completed the Production Scale Field Testing Phase. European Patent EP 1218508 granted (photocopy).

4

DNA Therapeutics - Market - Greenpak Biotech Ltd

http://www.greenpakbiotech.com/dna_therapeutics_market.htm

The China Pig Market. The China Pig Market. Source: FAS/USDA April 2008. China is the largest pig producer in the world. Grows about 50 % of the world s pigs. Demand for more "high-value" food like pork driven by:. Avian influenza outbreaks after which some consumers substituted pork for poultry. China s pig husbandry lacking in quality and productivity. Abundant resources committed to develop better feed additives and therapeutics. Ban on β-agonists, e.g., clenbutarol and ractopamine.

5

Site Map - Greenpak Biotech Ltd

http://www.greenpakbiotech.com/site_map.htm

169;2008 GreenPak Biotech Ltd. Tel: (852) 3943 6021 Fax: (852) 2994 4729 info@greenpakbiotech.com.

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169;2008 GreenPak Biotech Ltd. Tel: (852) 3943 6021 Fax: (852) 2994 4729 info@greenpakbiotech.com.

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