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Home | The Laboratory of Cell Physiology & Pathology

The Laboratory of Cell Physiology and Pathology. Microglia induce reversible death! Activated microglia induced reversible caspaase activation and phosphatidylserine exposure on targets PC12 cells, that was insufficient to induce cells death alone, but sufficient to induce phagocytosis of the target cells by the microglia. Want to know more? Are we living too long? Want to know more? The inflamed brain eats its neurons alive! Inflamed microglia become ravenous giants! Inflammation causes microglia to div...

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The Laboratory of Cell Physiology and Pathology. Microglia induce reversible death! Activated microglia induced reversible caspaase activation and phosphatidylserine exposure on targets PC12 cells, that was insufficient to induce cells death alone, but sufficient to induce phagocytosis of the target cells by the microglia. Want to know more? Are we living too long? Want to know more? The inflamed brain eats its neurons alive! Inflamed microglia become ravenous giants! Inflammation causes microglia to div...
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Home | The Laboratory of Cell Physiology & Pathology | guybrown.net Reviews

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The Laboratory of Cell Physiology and Pathology. Microglia induce reversible death! Activated microglia induced reversible caspaase activation and phosphatidylserine exposure on targets PC12 cells, that was insufficient to induce cells death alone, but sufficient to induce phagocytosis of the target cells by the microglia. Want to know more? Are we living too long? Want to know more? The inflamed brain eats its neurons alive! Inflamed microglia become ravenous giants! Inflammation causes microglia to div...

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Living End

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The Laboratory of Cell Physiology and Pathology. Praise for The Living End:. Brown makes an engaging and persuasive case for a complete rethink of the place of death in modern life.' James Wilsdon, The Financial Times. Lsquo;This book’s new view of death as a slow, analogue process, rather than a digital on/off switch, is intelligently, imaginatively and emotionally argued.’ Professor Chris Cooper, University of Essex. Remarkably accessible' Arthur Salm, San Diego Union Tribune. Century, holding out the ...

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Home | The Laboratory of Cell Physiology & Pathology

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The Laboratory of Cell Physiology and Pathology. Microglia induce reversible death! Activated microglia induced reversible caspaase activation and phosphatidylserine exposure on targets PC12 cells, that was insufficient to induce cells death alone, but sufficient to induce phagocytosis of the target cells by the microglia. Want to know more? Are we living too long? Want to know more? The inflamed brain eats its neurons alive! Inflamed microglia become ravenous giants! Inflammation causes microglia to div...

3

Sponsorship

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The Laboratory of Cell Physiology and Pathology. 0 (44) 1223 766055. Prof Guy Brown, Department of Biochemistry, Downing Site, Tennis Court Road, Cambridge, CB2 1QW, UK. Our research is entirely limited by the funding we get, and our ability to translate our research findings into treatments for disease is similarly limited by funding. Would you give money to help fight neurodegenerative disease, cancer or heart disease? 2013 Guy Brown Contact Me.

4

Research

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The Laboratory of Cell Physiology and Pathology. Inflammatory neurodegeneration in a culture of neurons, astrocytes and microglia. Video of microglia eating live neurons. Research in the Laboratory of Cell Physiology and Pathology. Current research interests are:. I) inflammatory neurodegeneration in the brain,. Ii) ischaemic and inflammatory damage to the cardiovascular system,. Iii) mitochondria, nitric oxide and cell death,. Iv) cell death in leukaemia, and. V) the future of death. Want to know more?

5

Publications | The Laboratory of Cell Physiology & Pathology

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The Laboratory of Cell Physiology and Pathology. Brown GC, Vilalta A (2015). How microglia kill neurons. Brain Res. 1628:288-97. Brown GC, Vilalta A, Fricker M (2015). Phagoptosis - Cell Death By Phagocytosis - Plays Central Roles in Physiology, Host Defense and Pathology. Curr Mol Med. 15:842-51. Neuroinflammation in Alzheimer's disease. Brown GC and Neher JJ (2014) Microglial phagocytosis of live neurons. Nat Rev. Neurosci. 15, 209-216. FEBS J. 280:4999-5014. Brown GC and Neher JJ (2012) Eaten alive!

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Home | The Laboratory of Cell Physiology & Pathology

The Laboratory of Cell Physiology and Pathology. Microglia induce reversible death! Activated microglia induced reversible caspaase activation and phosphatidylserine exposure on targets PC12 cells, that was insufficient to induce cells death alone, but sufficient to induce phagocytosis of the target cells by the microglia. Want to know more? Are we living too long? Want to know more? The inflamed brain eats its neurons alive! Inflamed microglia become ravenous giants! Inflammation causes microglia to div...

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