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Most drugs are small molecules on the order of 10 to 100 atoms. Monoclonal antibodies are enormous in comparison, on the order of 2000 to 20,000 atoms. Use of monoclonal antibodies. Current status of MAbs. Fighting Cancer With Monoclonal Antibodies. Panitumumab binds to the epidermal growth factor receptor (EGFR). It was approved by the FDA in 2006 for advanced colorectal cancer. Bevacizumab and Cetuximab were both approved by the FDA for colorectal cancer in 2004. Link Panitumumab, Cetuximab...
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