drugmetabolism.co.uk
Drug Metabolism: Database
http://www.drugmetabolism.co.uk/ReactionSelector2.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. How easy is it to find information about drug metabolism on the internet? Not so easy is the answer. Click here. Please create an account and help make this a valuable resource by expanding the content on this site. This site is best viewed using Internet Explorer 7, Firefox 2 or Netscape Navigator 8.
drugmetabolism.co.uk
Drug Metabolism Books
http://www.drugmetabolism.co.uk/Books.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. How easy is it to find information about drug metabolism on the internet? Not so easy is the answer. Click here. Please create an account and help make this a valuable resource by expanding the content on this site. This site is best viewed using Internet Explorer 7, Firefox 2 or Netscape Navigator 8.
drugmetabolism.co.uk
Drug Metabolism: Beta-lyase
http://www.drugmetabolism.co.uk/blyase.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Cysteine conjugate beta lyase. A lyase catalyzes the breaking of chemical bonds by means other than hydrolysis and oxidation. Lyase belongs to the lyase family and is classified as shown below:. EC 4 â Lyases (subdivided into 7 sub-classes). EC44 â Carbon-Sulphur lyases. EC44113 â cysteine-S-conjugate b. Elimination or transamination. Until 1978, no other metabolic fate of ...
drugmetabolism.co.uk
Home Page of Drug Metabolism and Other Biotransformations
http://www.drugmetabolism.co.uk/Default.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Apologies for being off-line for so long. There was a problem with the previous hosting company, which has now been resolved. Id="ctl00 ContentPlaceHolder1 btnForward" title="Next headline" /. Id="ctl00 ContentPlaceHolder1 btnLast" title="Last headline" /. InVitria Sponsors the 2010 Cell Culture Engineering Conference. Chemistry and Enzymology of Drug Metabolism:. The metabolom...
drugmetabolism.co.uk
Drug Metabolism: Oxidation
http://www.drugmetabolism.co.uk/Oxidation.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Chemistry of Oxidation Reactions. To find out more about the metabolism at these different centres, visit the database. Enzymes involved in Oxidation Reactions. How easy is it to find information about drug metabolism on the internet? Not so easy is the answer. Click here. Please create an account and help make this a valuable resource by expanding the content on this site.
drugmetabolism.co.uk
Drug Metabolism: UDP-Glucuronosyl Transferases
http://www.drugmetabolism.co.uk/UGT.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Glucuronidation is the major pathway in phase II metabolism and accounts for approximately 35% of drug conjugation. The reaction is the chemical binding of a substance to glucuronic acid, via a glycosidic bond. The product, a glucuronide conjugate, has enhanced water solubility, aiding elimination from the body. How easy is it to find information about drug metabolism on the in...
drugmetabolism.co.uk
Drug Metabolism: Other Phase I reactions
http://www.drugmetabolism.co.uk/Misc_phase_I.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Miscellaneous Phase I reactions. Miscellaneous Phase I Reactions. Some reactions just don't fit neatly into the oxidation, reduction or hydrolysis categories of phase I reactions, nor do they fit into phase II or phase II categories. Some of them are listed here and you can find examples of them in the database. Not so easy is the answer. Click here.
drugmetabolism.co.uk
Untitled Page
http://www.drugmetabolism.co.uk/MSCalc.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Calculate the Monoisotopic Mass for your Drug. Enter the empirical formula of the drug:. The monoisotopic mass is calculated using atomic masses of the most abundant isotope of each atom, accurate to at least 7 decimal places according to IUPAC. Rounding to six decimal places is applied after calculation of the monoisotopic molecular mass.
drugmetabolism.co.uk
Drug Metabolism: Overview of Phase I Metabolism - Chemistry and Enzymology
http://www.drugmetabolism.co.uk/Phase_I.aspx
Miscellaneous Phase I reactions. Cysteine conjugate beta lyase. Article of the Month. Submit an App. Note. Edit your App. Notes. Phase I metabolic reactions - the so called functionalisation reactions - incorporate or unmask functional groups, such as hydroxyl groups, primary amines, carboxylic acids, etc. Phase I reactions are typically:. Click on the links to find out more about the chemistry and the enzymes involved in these reactions. Not so easy is the answer. Click here.
