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Jump to main navigation and login. What are the protein hydroperoxides? Proteins represent a major target for reactive oxidants due to their high abundance in cells, plasma and most tissues, as well as their relatively high rates of reaction with many oxidants. Among potential oxidants of proteins the dominant role play reactive oxygen species (ROS) that are continously formed in many biological systems. Hydroxyl radical (. OH), superoxide radical anion (O. And singlet oxygen (.

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Jump to main navigation and login. What are the protein hydroperoxides? Proteins represent a major target for reactive oxidants due to their high abundance in cells, plasma and most tissues, as well as their relatively high rates of reaction with many oxidants. Among potential oxidants of proteins the dominant role play reactive oxygen species (ROS) that are continously formed in many biological systems. Hydroxyl radical (. OH), superoxide radical anion (O. And singlet oxygen (.

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Jump to main navigation and login. What are the protein hydroperoxides? Proteins represent a major target for reactive oxidants due to their high abundance in cells, plasma and most tissues, as well as their relatively high rates of reaction with many oxidants. Among potential oxidants of proteins the dominant role play reactive oxygen species (ROS) that are continously formed in many biological systems. Hydroxyl radical (. OH), superoxide radical anion (O. And singlet oxygen (.

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hydroperoxides.com

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Publications

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Jump to main navigation and login. 1 Michalski R., Michalowski B., Sikora A., Zielonka J., Kalyanaraman B. (2013) On the use of fluorescence lifetime imaging and dihydroethidium to detect superoxide in intact animals and ex vivo tissues: A reassessment Free Radic. Biol. Med. ASAP. 3 Michalski R., Zielonka J., Hardy M., Joseph J., Kalyanaraman B. (2013) Hydropropidine: A novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide Free Radic. Biol. Med. 54. 7 Błoch-Mechkour A., Ball...

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Introduction

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Jump to main navigation and login. What are the protein hydroperoxides? Proteins represent a major target for reactive oxidants due to their high abundance in cells, plasma and most tissues, as well as their relatively high rates of reaction with many oxidants. Among potential oxidants of proteins the dominant role play reactive oxygen species (ROS) that are continously formed in many biological systems. Hydroxyl radical (. OH), superoxide radical anion (O. And singlet oxygen (.

3

Seleno-Organic Compounds

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Jump to main navigation and login. It has been also demonstrated that other natural selenium-containing compounds like selenomethionine can reduce hydroperoxides in catalytic manner.

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Salen-Mn(III) Complexes

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Jump to main navigation and login. The salen-manganese complexes are known from their catalase and SOD like activity. The efficacy of these synthetic mimetics have been demonstrated in numerous pharmacological models for ROS-associated tissue damage and also in a large number of animal models of human diseases.

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Jump to main navigation and login. What are the protein hydroperoxides? Proteins represent a major target for reactive oxidants due to their high abundance in cells, plasma and most tissues, as well as their relatively high rates of reaction with many oxidants. Among potential oxidants of proteins the dominant role play reactive oxygen species (ROS) that are continously formed in many biological systems. Hydroxyl radical (. OH), superoxide radical anion (O. And singlet oxygen (.

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