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IA: known inhibitors of aminoacyl-tRNA synthetases

Aminoacyl-tRNA synthetases are a group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein [ 1. They are found in all living organisms, and their key mode of action is graphically depicted in Figure 1. We searched for known inhibitors of aminoacyl-tRNA synthetases in articles published from 2001 to 2006, found by PubMed search engine. Reviews published before 2001 were also taken into account in creation of the database of inhibitors of aminoacyl-tRNA ...

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Aminoacyl-tRNA synthetases are a group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein [ 1. They are found in all living organisms, and their key mode of action is graphically depicted in Figure 1. We searched for known inhibitors of aminoacyl-tRNA synthetases in articles published from 2001 to 2006, found by PubMed search engine. Reviews published before 2001 were also taken into account in creation of the database of inhibitors of aminoacyl-tRNA ...
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IA: known inhibitors of aminoacyl-tRNA synthetases | ia.bioinfo.pl Reviews

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Aminoacyl-tRNA synthetases are a group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein [ 1. They are found in all living organisms, and their key mode of action is graphically depicted in Figure 1. We searched for known inhibitors of aminoacyl-tRNA synthetases in articles published from 2001 to 2006, found by PubMed search engine. Reviews published before 2001 were also taken into account in creation of the database of inhibitors of aminoacyl-tRNA ...

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IA: known inhibitors of aminoacyl-tRNA synthetases

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Aminoacyl-tRNA synthetases are a group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein [ 1. They are found in all living organisms, and their key mode of action is graphically depicted in Figure 1. We searched for known inhibitors of aminoacyl-tRNA synthetases in articles published from 2001 to 2006, found by PubMed search engine. Reviews published before 2001 were also taken into account in creation of the database of inhibitors of aminoacyl-tRNA ...

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IA: known inhibitors of aminoacyl-tRNA synthetases

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Structures (conformation A and B) from literature (0000-0239) in one sdf file. Smiles from literature (0000-0239) in one file.

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IA: known inhibitors of aminoacyl-tRNA synthetases

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Szymanski,M., Deniziak,M., Barciszewski,J. (2000) The new aspects of aminoacyl-tRNA synthetases. Acta Biochim. Pol. Kim,SE., Kim,S.Y., Kim,S., Kang,T., Lee,J. (2005) Deoxyribosyl analogues of methionyl and isoleucyl sulfamate adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases. Bioorg. Med. Chem. Lett. Petraitis,V., Petraitiene,R., Kelaher,am, Sarafandi,A.A., Sein,T., Mickiene,D., Bacher,J., Groll,A.H., Walsh,T.J. (2004) Efficacy of PLD-11...Kanamaru,T., Nakano,Y., Toyoda,Y&...Yu,XY...

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IA: known inhibitors of aminoacyl-tRNA synthetases

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We would like to find a molecule which has NH. Anywhere in the molecule that is has NH3 substring in smile notation (for all synthetases and references):. In the left-hand input field write %NH3 %. Means 'any string', right-hand input field should be left blank. The fields for all synthetases and all references should be checked (default). As the result we get 34 molecules. In the left-hand input field write OC(=O)%. Uncheck all references (Check/Uncheck button) and check only PheRS and MetRS.

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IA: known inhibitors of aminoacyl-tRNA synthetases

Aminoacyl-tRNA synthetases are a group of enzymes that ensure the fidelity of transfer of genetic information from the DNA into the protein [ 1. They are found in all living organisms, and their key mode of action is graphically depicted in Figure 1. We searched for known inhibitors of aminoacyl-tRNA synthetases in articles published from 2001 to 2006, found by PubMed search engine. Reviews published before 2001 were also taken into account in creation of the database of inhibitors of aminoacyl-tRNA ...

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