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We’re advancing the clinical application of immune tolerance. | Immune Tolerance Network

The Immune Tolerance Network is a collaborative network for clinical research focused on the development of therapeutic approaches for asthma and allergy, autoimmune diseases, type 1 diabetes and solid organ transplantation that lead to immune tolerance.

http://www.immunetolerance.org/

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We’re advancing the clinical application of immune tolerance. | Immune Tolerance Network | immunetolerance.org Reviews
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The Immune Tolerance Network is a collaborative network for clinical research focused on the development of therapeutic approaches for asthma and allergy, autoimmune diseases, type 1 diabetes and solid organ transplantation that lead to immune tolerance.
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We’re advancing the clinical application of immune tolerance. | Immune Tolerance Network | immunetolerance.org Reviews

https://immunetolerance.org

The Immune Tolerance Network is a collaborative network for clinical research focused on the development of therapeutic approaches for asthma and allergy, autoimmune diseases, type 1 diabetes and solid organ transplantation that lead to immune tolerance.

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members.immunetolerance.org members.immunetolerance.org

Immune Tolerance Network

This is a public or shared computer. Select this option if you are connecting from a public computer. Be sure to log off and close all browser windows to end your session. Read about the security risks. Of using a public computer. This is a private computer. Select this option if you are the only person using this computer. This option provides additional time of inactivity before automatically logging you off. Call 800-624-4308 or mail itsupport@immunetolerance.org.

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ITN Registry of Tolerant Kidney Transplant Recipients

For your interest in the ITN Registry of Tolerant Kidney Transplant Recipients. The ITN Registry is seeking to identify and study these rare patients. The investigators of this study believe that these rare, naturally tolerant individuals, will help us better understand how immune tolerance is created and maintained, providing new clues to organ transplantation without immunosuppression. If you believe you may qualify for this study or know someone who you believe meets these requirements, please contact:.

rave.immunetolerance.org rave.immunetolerance.org

Clinical Trial Information - RAVE - Rituximab for ANCA-Associated Vasculitis

Thank you for your interest in the RAVE Trial. RAVE is an international Phase II/III double-blind, placebo-controlled trial of the anti-CD20 monoclonal antibody rituximab in ANCA-associated vasculitis (AAV), specifically. The trial is being conducted by the Immune Tolerance Network (ITN), with support from the National Institutes of Health, the Food and Drug Administration and Genentech, Inc. More information may be found on the accompanying pages. 2005, Immune Tolerance Network.

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immunetolerance.org immunetolerance.org
1

Early Consumption of Peanuts Prevents Peanut Allergy in High-Risk Infants | Immune Tolerance Network

https://www.immunetolerance.org/news/2015/02/early-consumption-peanuts-prevents-peanut-allergy-high-risk-infants

Early Consumption of Peanuts Prevents Peanut Allergy in High-Risk Infants. February 23, 2015 -. The results of the Immune Tolerance Network’s (ITN) Learning Early About Peanut (LEAP) study published today in the. New England Journal of Medicine. Of the children who avoided peanut, 17% developed peanut allergy by the age of 5 years. Remarkably, only 3% of the children who were randomized to eating the peanut snack developed allergy by age 5. Therefore, in high-risk infants, sustained consumption o...For d...

2

Working at the ITN | Immune Tolerance Network

https://www.immunetolerance.org/about-us/careers

Working at the ITN. The Immune Tolerance Network (ITN) offers opportunities in many career areas: clinical trials management, laboratory research management, data management and analysis, research administration and finance, technical staff and others. Positions at ITN are located at one of our three offices, in Seattle, WA, San Francisco, CA or Bethesda, MD and staff are employed directly by one of three different institutions: Benaroya Research Institute. University of California at San Francisco.

3

Partner with the ITN | Immune Tolerance Network

https://www.immunetolerance.org/professionals/about-us/partner-itn

Partner with the ITN. The ITN develops, funds and conducts clinical trials with integrated mechanistic analyses by fostering collaboration between academic, governmental and industry researchers. The ITN's development model is a unique, interactive process that facilitates the design of high-quality, mechanism-driven tolerance trials. This process capitalizes on ITN's wide-ranging, multidisciplinary expertise provided by an advisory board of highly respected faculty from institutions worldwide.

4

ITN Opens Pilot Study to Compare Allergen Challenge Methods (CAT EEC Study) | Immune Tolerance Network

https://www.immunetolerance.org/news/2015/02/itn-opens-pilot-study-compare-allergen-challenge-methods-cat-eec-study

ITN Opens Pilot Study to Compare Allergen Challenge Methods (CAT EEC Study). February 4, 2015 -. On Monday the ITN opened a new pilot study to compare two different methods for assessing allergic responses: environmental exposure chambers and nasal allergen challenges. The CAT EEC study. The Immune Tolerance Network. And is sponsored by the National Institute of Allergy and Infectious Diseases. Part of the National Institutes of Health. 2016 Immune Tolerance Network.

5

Leadership | Immune Tolerance Network

https://www.immunetolerance.org/professionals/about-us/people

Gerald Nepom, MD, PhD. E William St. Clair, MD. Network Deputy Director, Clinical Affairs. Laurence Turka, MD. Network Deputy Director, Biomarker and Discovery Research. Vince Carey, PhD. Scientific Director, Bioinformatics. Peter Sayre, MD, PhD. Executive Director, Clinical Trials Group and Chief Medical Officer. Alan Krensky, MD. Alice Long, PhD. Allan Kirk, MD, PhD. Amit Bar-Or, MD. Montreal Neurological Institute and Hospital, McGill University. Arthur Caplan, PhD. Beena Akolkar, PhD. David Fox, MD.

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The START Trial - Frequently Asked Questions (FAQ)

http://www.type1diabetestrial.org/faq.html

A clinical research consortium sponsored by NIAID and JDRF. Note: This document is also available in pdf format. What is the purpose of this research study? Will I/my child need to be hospitalized? Yes All participants are admitted to the hospital to receive the study drug (or placebo), which is given intravenously in four infusions. Participants can expect to spend a total of 5-8 days in the hospital. What does intensive diabetes management involve? How often will I need to visit the clinic? Study visit...

extendstudy.org extendstudy.org

Eligibility | EXTEND

http://www.extendstudy.org/eligibility

Skip to main content. A clinical research cooperative sponsored by NIAID. Preserving beta cell function with tocilizumab in new onset type 1 diabetes. About Type 1 Diabetes. You may be eligible to participate in the EXTEND Study if you:. Are male or female, aged 18-45. Have been diagnosed with type 1 diabetes within the last 3 months. Test positive for at least one type 1 diabetes-related autoantibody (a blood test is done to determine this). Are in good general health. 2011 Immune Tolerance Network.

extendstudy.org extendstudy.org

Study Locations | EXTEND

http://www.extendstudy.org/study-locations

Skip to main content. A clinical research cooperative sponsored by NIAID. Preserving beta cell function with tocilizumab in new onset type 1 diabetes. About Type 1 Diabetes. For more information about the EXTEND study or to find out if you are eligible, please contact the site closest to you. 300 Pasteur Drive ,. Contact for more information:. University of California San Francisco. UCSF Mission Hall,. 550 16th St, 4th Floor MS 0434. Contact for more information:. 2 Church Street South ,. 1 Joslin Place ,.

extendstudy.org extendstudy.org

About Type 1 Diabetes | EXTEND

http://www.extendstudy.org/about-type-1-diabetes

Skip to main content. A clinical research cooperative sponsored by NIAID. Preserving beta cell function with tocilizumab in new onset type 1 diabetes. About Type 1 Diabetes. About Type 1 Diabetes. What is Type 1 Diabetes? Researchers have found that even a small amount of insulin produced by a relatively small number of beta cells can be of great benefit to people with type 1 diabetes. It may help reduce the need for injected insulin and help maintain good control of blood glucose levels. In turn...For t...

type1diabetestrial.org type1diabetestrial.org

The START Trial - About Us

http://www.type1diabetestrial.org/aboutus.html

A clinical research consortium sponsored by NIAID and JDRF. START is a clinical research study conducted by the Immune Tolerance Network together with researchers from eight clinical centers. The study is sponsored by the US National Institute of Allergy and Infectious Diseases, with support from the National Institute of Diabetes and Digestive and Kidney Diseases and the Juvenile Diabetes Research Foundation. The investigators also wish to thank LifeScan, Inc. For their support of this study. The Immune...

leapstudy.co.uk leapstudy.co.uk

LEAP Study Results | LEAP

http://leapstudy.co.uk/leap-study-results

Skip to main content. Developing, funding and conducting clinical trials in immune tolerance. Learning Early About Peanut Allergy. LEAP is no longer accepting study participants. The results of the Immune Tolerance Network’s (ITN) Learning Early About Peanut (LEAP),. Discussed on February 23, 2015 at the American Academy of Allergy, Asthma and Immunology Annual Meeting and. New England Journal of Medicine. Of the children who avoided peanut, 17% developed peanut allergy by the age of 5 years. Remarka...

leapstudy.co.uk leapstudy.co.uk

Other Allergy Studies | LEAP

http://leapstudy.co.uk/other-allergy-studies

Skip to main content. Developing, funding and conducting clinical trials in immune tolerance. Learning Early About Peanut Allergy. LEAP is no longer accepting study participants. Additional Allergy Research Studies Being Conducted by the ITN. LEAP-ON Persistence of Oral Tolerance to Peanut. This is a follow-on study to the ITN's LEAP trial to evaluate the persistence of tolerance to peanut, and whether continued consumption of peanuts is required in order to be able to safely eat peanuts. The goal of thi...

leapstudy.co.uk leapstudy.co.uk

About LEAP | LEAP

http://leapstudy.co.uk/about-leap

Skip to main content. Developing, funding and conducting clinical trials in immune tolerance. Learning Early About Peanut Allergy. LEAP is no longer accepting study participants. Welcome to the LEAP Study. Given its severe nature and the absence of a cure, prevention remains our best hope to reduce peanut allergy in children. But how exactly can peanut allergy be prevented? Does eating peanuts during infancy make the immune system tolerant or sensitive to peanuts consumed later on? The proportion of each...

leapstudy.co.uk leapstudy.co.uk

About ITN | LEAP

http://leapstudy.co.uk/about-itn

Skip to main content. Developing, funding and conducting clinical trials in immune tolerance. Learning Early About Peanut Allergy. LEAP is no longer accepting study participants. The Immune Tolerance Network. The ITN is funded by a grant from the National Institute of Allergy and Infectious Disease of the National Institutes of Health awarded to the Benaroya Research Institute. Seattle, WA), in partnership with the University of California San Francisco. And the Massachusetts General Hospital. Children a...

leapstudy.co.uk leapstudy.co.uk

Peanut Allergy | LEAP

http://leapstudy.co.uk/peanut-allergy

Skip to main content. Developing, funding and conducting clinical trials in immune tolerance. Learning Early About Peanut Allergy. LEAP is no longer accepting study participants. Peanut allergies are very similar to other allergies, which are abnormal responses by the body’s immune system to otherwise harmless substances. In a peanut allergic child, when the immune system detects peanut protein, antibodies are produced that trigger an inappropriate immune response. Why is peanut allergy a problem? Childr...

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Home - 3rd International Conference on Immune Tolerance

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We’re advancing the clinical application of immune tolerance. | Immune Tolerance Network

Developing, funding and conducting clinical trials in immune tolerance. Learn about our research. Enroll in a Clinical Trial. ITN's trials aim to identify therapies that preserve beta cell function. ITN is focused on achieving durable desensitization to allergen exposure. ITN's goal is to induce tolerance of transplanted organs without lifelong immunosuppression. ITN is identifying therapies to achieve durable clinical remission of autoimmune disease. Access raw data, analysis and clinical specimens.

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