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Reeves Lab

Quantitative phenotypic assays that we have developed give a precise and sensitive readout of the relative effects on phenotype when overlapping subsets of genes are at dosage imbalance. Developmental analyses of these traits are underway to identify the timing and location of divergence between trisomic and euploid fetuses. More. Roger H. Reeves, Ph.D. Johns Hopkins Univ. Schl. of Medicine. Department of Physiology and. McKusick-Nathans Institute for Genetic. 725 North Wolfe Street. Baltimore, MD 21025.

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Reeves Lab | inertia.bs.jhmi.edu Reviews

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Quantitative phenotypic assays that we have developed give a precise and sensitive readout of the relative effects on phenotype when overlapping subsets of genes are at dosage imbalance. Developmental analyses of these traits are underway to identify the timing and location of divergence between trisomic and euploid fetuses. More. Roger H. Reeves, Ph.D. Johns Hopkins Univ. Schl. of Medicine. Department of Physiology and. McKusick-Nathans Institute for Genetic. 725 North Wolfe Street. Baltimore, MD 21025.

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Reeves Lab | inertia.bs.jhmi.edu Reviews

https://inertia.bs.jhmi.edu

Quantitative phenotypic assays that we have developed give a precise and sensitive readout of the relative effects on phenotype when overlapping subsets of genes are at dosage imbalance. Developmental analyses of these traits are underway to identify the timing and location of divergence between trisomic and euploid fetuses. More. Roger H. Reeves, Ph.D. Johns Hopkins Univ. Schl. of Medicine. Department of Physiology and. McKusick-Nathans Institute for Genetic. 725 North Wolfe Street. Baltimore, MD 21025.

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inertia.bs.jhmi.edu

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Reeves Lab

http://inertia.bs.jhmi.edu/publications/index.html

Selected publications (from 175); More than 8000 citations, h factor = 48 (Google Scholar, August 2015). Dutka, T., Hallberg, D. and Reeves, R. H. Chronic up-regulation of the SHH pathway normalizes some developmental effects of trisomy in Ts65Dn mice. Mech Dev 135, 68-80, doi:10.1016/j.mod.2014.11.004 (2015). [ PDF. Ramachandran D, Mulle JG, Locke AE, Bean LJ, Rosser TC, Bose P, Dooley KJ, Cua CL, Capone GT, Reeves RH. 2012 Genetic modifiers predisposing to congenital heart disease in the sensitized Dow...

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Reeves Lab

http://inertia.bs.jhmi.edu/people/reeves.html

Roger Harper Reeves, Ph.D. Department of Physiology, P202. Johns Hopkins Univ. Schl. of Medicine. 725 N Wolfe Street. Baltimore, MD 21205. 410) 955-6621, FAX (443) 287-0508. 1983 Ph.D., University of Maryland, College Park, MD/ Nat'l. Cancer Institute, NIH, Molecular Genetics. 1975 B.S., Bowling Green State Univ., Bowling Green, Ohio, Biology/Chemistry minor. 2001- Core Faculty, McKusick-Nathans Institute for Genetic Medicine, The Johns Hopkins Univ. Schl. Med. (JHUSOM),. Faculty director, The Johns Hopk...

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Reeves Lab

http://inertia.bs.jhmi.edu/people/index.html

Graduate student, IGM. Fabian Fernandez, Ph.D. Graduate Student, IGM. Donna Klinedinst, Ph.D. Graduate Student, IGM. Roger H. Reeves, Ph.D. Meifang Xiao, Ph.D. Annan’s graduation, 2011.

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Reeves Lab

http://inertia.bs.jhmi.edu/ds/index.html

40% of children born with Down syndrome (or trisomy 21) have a congenital heart defect (CHD). The most common form of CHD in Down syndrome is an atrioventricular septal defect (or AVSD). Children with Down syndrome are 2000 times more likely to have a complete AVSD than children without Down syndrome. Researchers are conducting a multi-site study to identify genetic risk factors for congenital heart defects in people with Down syndrome. Who can participate in this study? Sign a consent form. Numbers inst...

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changingmindsaboutdownsyndrome.blogspot.com

Changing Minds Around the World: What's all the talk about sonic hedgehog?

http://changingmindsaboutdownsyndrome.blogspot.com/2013/09/what-all-talk-about-sonic-hedgehog.html

Sunday, September 15, 2013. Whats all the talk about sonic hedgehog? Here is the article from Johns Hopkins (ie. the original) No one said it was a cure just another approach for improvement. EXPERIMENTAL COMPOUND REVERSES DOWN SYNDROME-LIKE LEARNING DEFICITS IN MICE. Cerebellums from Down syndrome-like mice treated with a new compound (left), untreated mice (middle) and normal mice (right). Mice with a Down syndrome-like condition. On the day of birth. As they report in the Sept. 4 issue of. A professor...

getahead.psu.edu

Richtsmeier Lab - About Page

http://getahead.psu.edu/about_new.html

Lab is located in the Department of Anthropology. At the Pennsylvania State University. Where Dr. Richtsmeier is Distinguished Professor of Anthropology and a member of the faculty of graduate program in Molecular Cellular and Integrated BioSciences (MCIBS). Dr. Richtsmeier is adjunct professor in the Center for Functional Anatomy and Evolution. At the Johns Hopkins University School of Medicine in Baltimore, MD and a member of the faculty of the Collaboration for Craniofacial Development and Disorders.

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About Down Syndrome

http://www.dsapgh.org/about-down-syndrome.html

If you are interested in volunteering for the Down Syndrome Association of Pittsburgh. We are looking for event volunteers, family mentors, website contributors, etc. 9th Annual DSAP Golf Outing. Friday, June 12, 2015. 4th Annual DSAP Idlewild Family Fun Day. Sunday, August 9, 2015. Three Rivers DASH for Down Syndrome. Saturday, October 10, 2015. Please come see us soon, as we build out these unique features of our site. Please come see us soon, as we build out these unique features of our site. Transloc...

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inertia.bs.jhmi.edu

Reeves Lab

Quantitative phenotypic assays that we have developed give a precise and sensitive readout of the relative effects on phenotype when overlapping subsets of genes are at dosage imbalance. Developmental analyses of these traits are underway to identify the timing and location of divergence between trisomic and euploid fetuses. More. Roger H. Reeves, Ph.D. Johns Hopkins Univ. Schl. of Medicine. Department of Physiology and. McKusick-Nathans Institute for Genetic. 725 North Wolfe Street. Baltimore, MD 21025.

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