INstruct is a database of high-quality protein interactome networks annotated to structural resolution. The interactions shown on this site have been curated from some of the most popular interaction databases and filtered to reflect only those interactions that meet strict quality criteria. NEW: Search for structural interactions in SIX species!
http://instruct.yulab.org/
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INstruct: a database of 3D protein interactome networks with structural resolution | instruct.yulab.org Reviews
https://instruct.yulab.org
INstruct is a database of high-quality protein interactome networks annotated to structural resolution. The interactions shown on this site have been curated from some of the most popular interaction databases and filtered to reflect only those interactions that meet strict quality criteria. NEW: Search for structural interactions in SIX species!
instruct.yulab.org
INstruct: a database of 3D protein interactome networks with structural resolution
http://instruct.yulab.org/about.html
A database of 3D protein interactome networks with structural resolution. A paper describing INstruct is published in Bioinformatics. For each species, to construct a protein interactome network with structural resolution, we first compiled a list of high-quality binary interactions extracted from high-throughput, high-quality yeast two-hybrid (Y2H) assays and from eight major protein-protein interaction databases: BioGrid. Release of December 2011) or iPfam. Release 21). The set of Pfam domains on p...
INstruct: a database of 3D protein interactome networks with structural resolution
http://instruct.yulab.org/downloads.html
A database of 3D protein interactome networks with structural resolution. Upload a file of gene or protein identifiers separated by new line characters and/or any common delimiter. From here you can browse available interactome network downloads. Create a custom download by using the batch function above. Structurally resolved interactome network with domain amino acid locations. Structurally resolved interactome network with domain amino acid locations. PDB Amino Acid Mappings.
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High-quality Interactomes
http://hint.yulab.org/faq.html
1 Database query: Gene ids used in this database (Uniprot ids are allowed for all organisms). Entrez gene ids/Gene names. Entrez gene ids/Gene names. 2 How to use. A Input your favourite protein(s) separated by semicolons. B Choose the organism of your interest. C Choose the interaction type. D Input the minimum number of discrete publications that should confirm the interactions. Use semicolons to separate multiple entries. A maximum of 10 queries should be used at a time. Das J and Yu H.
High-quality Interactomes
http://hint.yulab.org/index.html
Enter proteins (max 10). Separate multiple entries by ";". Cutoff number of publications. Separate multiple entries by ";". Pull-down/Anti-bait or Anti-tag co-ip. Pull-down/Anti-bait or Anti-tag co-ip. Ticking this disables the high-quality filter). HINT has been updated. Version 3 is now online. Our databases are updated nightly. How to use HINT. A Input your favourite protein(s) separated by semicolons. B Choose the organism of your interest. C Choose the interaction type. Visit the Yu Lab website.
High-quality Interactomes
http://hint.yulab.org/batch.html
Batch Downloads of Protein Interactomes. Click here to download the entire high-quality binary interactome for H. sapiens. Click here to download the entire high-quality binary interactome for S. cerevisiae. Click here to download the entire high-quality binary interactome for S. pombe. Click here to download the entire high-quality binary interactome for M. musculus. Click here to download the entire high-quality binary interactome for D. melanogaster. Click here to download the entire high-quality co-c...
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INstruct: a database of 3D protein interactome networks with structural resolution
A database of 3D protein interactome networks with structural resolution. A database of high-quality protein interactome networks annotated to 3D structural resolution. We currently catalogue 6585 human, 644 A. thaliana. 1273 S. cerevisiae. And 37 S. pombe. Structurally resolved interactions. The interactions shown on this site have been curated from some of the most popular interaction databases and filtered to reflect only binary interactions that meet our strict. Compile PDB co-crystal structures.
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