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IntOGen - mutational cancer drivers database

Cancer driver mutations

http://www.intogen.org/

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CONTACTS AT INTOGEN.ORG

Universitat Pompeu Fabra

Nuria Lopez Bigas

Dr. A●●●●●er 88

Bar●●●ona , Barcelona, 08003

ES

34.9●●●●0507
34.9●●●●0550
do●●●●●●●●●●●●●@acens.com

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Universitat Pompeu Fabra

Nuria Lopez Bigas

Dr. A●●●●●er 88

Bar●●●ona , Barcelona, 08003

ES

34.9●●●●0507
34.9●●●●0550
do●●●●●●●●●●●●●@acens.com

View this contact

Universitat Pompeu Fabra

Nuria Lopez Bigas

Dr. A●●●●●er 88

Bar●●●ona , Barcelona, 08003

ES

34.9●●●●0507
nu●●●●●●●●●@upf.edu

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IntOGen - mutational cancer drivers database | intogen.org Reviews
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Cancer driver mutations
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IntOGen - mutational cancer drivers database | intogen.org Reviews

https://intogen.org

Cancer driver mutations

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intogen.org intogen.org
1

IntOGen - Cancer Mutations Browser

https://www.intogen.org/downloads

Catalog of driver mutations (2016.5). This database contains the results of the driver analysis performed by the Cancer Genome Interpreter across 6,792 exomes of a pan-cancer cohort of 28 tumor types. Validated oncogenic mutations are identified according to the state-of-the-art clinical and experimental data, whereas the effect of the mutations of unknown significance is predicted by the OncodriveMUT method. Sign in to download. Cancer Drivers Database (2014.12). Rubio-Perez, C., Tamborero, D., ...It ch...

2

IntOGen - Cancer Mutations Browser

https://www.intogen.org/about

The Biomedical Genomics Group. Is a research group integrated in the Research Unit on Biomedical Informatics ( GRIB. Of the University Pompeu Fabra ( UPF. The lab is located in the Biomedical Research Park in Barcelona ( PRBB. Our main research interest is the computational study of cancer from a genomics perspective (see details in Projects. In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities. Cancer Cell 27 (2015), pp. 382-396. Has been used for...

3

IntOGen - Cancer Mutations Browser

https://www.intogen.org/analysis

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bg.upf.edu bg.upf.edu

New IntOGen web to explore driver genes across cancer types » Computational Oncogenomics

http://bg.upf.edu/blog/2015/03/new-intogen-web-to-explore-driver-genes-across-cancer-types

The biomedical genomics blog. New IntOGen web to explore driver genes across cancer types. Coinciding with the publication of our latest paper, on Monday (9 March 2015) ( See blog post. We have crafted a new IntOGen interface which presents the results of the analysis of somatic mutations across almost 7000 cancer samples from 28 different cancer types to identify driver genes. The analysis identified 459. On each page for a gene, cancer type or a project you will find multiple reports, such as a cancers...

bg.upf.edu bg.upf.edu

In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities » Computational Oncogenomics

http://bg.upf.edu/blog/2015/03/in-silico-prescription-of-anticancer-drugs-to-cohorts-of-28-tumor-types-reveals-novel-targeting-opportunities

The biomedical genomics blog. In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals novel targeting opportunities. We are pleased to announce the publication of our paper. Describing the landscape of anti-cancer targeted therapeutic opportunities across a cohort of patients of twenty eight of the most prevalent cancers. Prescription approach to obtain the landscape of targeted drugs against cancer driver alterations, composed of three main steps. 1) Discover the actionable.

bg.upf.edu bg.upf.edu

OncodriveROLE predicts activating and loss of function cancer driver genes » Computational Oncogenomics

http://bg.upf.edu/blog/2014/08/oncodriverole-predicts-activating-and-loss-of-function-cancer-driver-genes

The biomedical genomics blog. OncodriveROLE predicts activating and loss of function cancer driver genes. We are pleased to announce that the Oncodrive methods family has a new member: OncodriveROLE. An approach to classify cancer drivers into loss of function and activating roles. OncodriveROLE joins and complements the previously developed methods that identify cancer driver genes from the list of somatic mutations in cohort of tumors (OncodriveCLUST and OncodriveFM). And freely available online. I...

bg.upf.edu bg.upf.edu

Biomedical Genomics Group

http://bg.upf.edu/group/tools.php

In our group we have developed several methods and tools for the analysis and visualization of cancer genomics data. Below is a description of the main tools and methods:. A discovery tool for cancer researchers. To identify cancer drivers: OncodriveFM. And classify them according to their role OncodriveROLE. Methods to assess the functional impact of mutations: Condel. Sample Level Enrichment Analysis: SLEA. Integrative OncoGenomics (IntOGen: http:/ www.intogen.org. The IntOGen Mutation Analysis Pipeline.

genewiki.com genewiki.com

What is oncogenomics? - Genewiki.com

http://genewiki.com/index.php/Special:Random

Is relatively new sub-field of genomics, which applies high throughput technologies to characterize genes associated with cancer. Overall goals of oncogenomics. Bionformatics and functional analysis of oncogenes. Databases for Cancer Research. Current technologies being used in Oncogenomics. Research examining the genomes and transcriptomes of cancer cells are currently extensively complemented by state of the art technologies. High-throughput DNA sequencing technologies. This technique measures the DNA ...

culturalgenomics.org culturalgenomics.org

What is oncogenomics? - Bio.pe

http://www.culturalgenomics.org/index.php/Special:Random

Is relatively new sub-field of genomics, which applies high throughput technologies to characterize genes associated with cancer. Overall goals of oncogenomics. Bionformatics and functional analysis of oncogenes. Databases for Cancer Research. Current technologies being used in Oncogenomics. Research examining the genomes and transcriptomes of cancer cells are currently extensively complemented by state of the art technologies. High-throughput DNA sequencing technologies. This technique measures the DNA ...

mpschr.com mpschr.com

mpschr.com - Another no purpose web site. Michael P Schroeder

http://www.mpschr.com/projects

I work am doing my PhD as a bioinformatician at the Biomedical Genomics Group. In Barcelona and am involved in various projects. Some of which, listed below. A framework for analysis and visualization of multidimensional genomic data using interactive heat-maps. So far I have been able to contribute to the scientific literature. And also blog entries at the Biomedical Genomics group. But I also keep myself busy during my "free" time:. Go, Teachers, Go! Is a content managing system to bet on football.

medbioinformatics.eu medbioinformatics.eu

Useful Links | MedBioinformatics

http://www.medbioinformatics.eu/useful-links

News & Media. News & Events. News & Media. News & Events. A discovery tool for cancer researchers to find driver mutations in genes and pathways ( https:/ www.intogen.org/. A discovery platform integrating information on gene-disease associations (GDAs) from several public data sources and the literature ( http:/ www.disgenet.org/. Individualized Systems Medicine ( ISM. In AML project ( https:/ www.fimm.fi/en/research/grand-challenge-programmes/individualized-systems-medicine-cancer. Danish Council for S...

biobits.org biobits.org

IntOGen - Interview with Nuria Lopez-Bigas

http://biobits.org/intogen-lopez-bigas.html

A Blog about bioinformatics, scientific computing and cancer genomics. IntOGen - Interview with Nuria Lopez-Bigas. October 25, 2013. This week marks a slightly different direction for biobits.org. For some time, I have been thinking of interviewing practitioners in the world of cancer genomics, and getting their perspectives. David Tamborero, et al., Comprehensive identification of mutational cancer driver genes across 12 tumor types. Scientific Reports, 2013. Nature Methods, 2013. We designed IntOGen-mu...

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IntOGen - mutational cancer drivers database

I would like to be informed of important updates. I accept the Terms of Use. Cancer drivers in thyroid carcinoma. Drivers table in the TCGA ovary dataset. Drivers frequency in the ovarian cancer. Most mutated genes in breast Broad dataset. Recurrence of TP53 mutations. Mutation frequency of VHL. Mutation distribution of BRAF in breast cancer. Mutations plot of IDH1 in Glioblastoma. Mutations in EB1-binding domain of APC. FLT3 mutations in AML. Paste this link in an email or IM. In driver genes 21648.

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