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IRESSA® (gefitinib)

IRESSA® (gefitinib) is a treatment for patients with metastatic non-small cell lung cancer (NSCLC) who have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations.

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IRESSA® (gefitinib) | iressa-usahcp.com Reviews
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IRESSA® (gefitinib) is a treatment for patients with metastatic non-small cell lung cancer (NSCLC) who have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations.
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IRESSA® (gefitinib) | iressa-usahcp.com Reviews

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IRESSA® (gefitinib) is a treatment for patients with metastatic non-small cell lung cancer (NSCLC) who have EGFR exon 19 deletions or exon 21 (L858R) substitution mutations.

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1

Safety & Side Effects of IRESSA® (gefitinib)

https://www.iressa-usahcp.com/safety-side-effects.html

Indication and Limitation of Use. For US Healthcare Professionals. Go to Patient Site. Indication and Limitation of Use. Ordering and Patient Access. Proven safety and tolerability. The IRESSA safety profile was derived from 3 clinical trials. The safety of IRESSA is based on the data from 2462 patients with NSCLC who received IRESSA 250-mg daily monotherapy in 3 randomized clinical studies (1 placebo-controlled. And 2 active-comparator studies). Grade 3/4 skin reactions occurred at 2%. Patients and 2&#4...

2

Sitemap | IRESSA® (gefitinib)

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Indication and Limitation of Use. For US Healthcare Professionals. Go to Patient Site. Indication and Limitation of Use. Ordering and Patient Access. Ordering and Patient Access. AstraZeneca US Corporate Site. Interstitial Lung Disease (ILD) or ILD-like. Gastrointestinal perforation occurred in three (0.1%) of 2462 IRESSA patients. Permanently discontinue IRESSA in patients who develop gastrointestinal perforation. Bullous conditions including toxic epidermal necrolysis, Stevens Johnson syndrome and eryt...

3

IRESSA® (gefitinib) | Metastatic NSCLC Treatment For EGFR Mutation

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Indication and Limitation of Use. For US Healthcare Professionals. Go to Patient Site. Indication and Limitation of Use. Ordering and Patient Access. IRESSA is indicated for the first-line. Treatment of patients with metastatic non-small. Cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test. Interstitial Lung Disease (ILD) or ILD-like. Ocular disorders [keratitis (0.1%), corne...

4

IRESSA® (gefitinib) Dosage Information

https://www.iressa-usahcp.com/gefitinib-dosage.html

Indication and Limitation of Use. For US Healthcare Professionals. Go to Patient Site. Indication and Limitation of Use. Ordering and Patient Access. Once-daily dosing with or without food. The recommended dose of IRESSA is 250 mg once daily until disease progression. Select patients for the first-line treatment of metastatic NSCLC with IRESSA based on the presence of EGFR exon 19 deletion or exon 21 (L858R) substitution mutations in their tumor. IRESSA is a once-daily tablet. No titration is needed.

5

IRESSA® (gefitinib) Efficacy Data

https://www.iressa-usahcp.com/gefitinib-efficacy.html

Indication and Limitation of Use. For US Healthcare Professionals. Go to Patient Site. Indication and Limitation of Use. Ordering and Patient Access. IRESSA is a proven first-line agent in patients with metastatic NSCLC whose tumors harbor EGFR exon 19 deletions or exon 21 (L858R) substitution mutations. Read the results of the IFUM. Efficacy was demonstrated in the IFUM* study. Similar response was seen in all patient subgroups. 5 out of 10 patients achieved ORR as measured by BICR. IRESSA efficacy was ...

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IRESSA® (gefitinib) Treatment

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Indication and Limitation of Use. Go to US Healthcare Professional Site. Go to HCP Site. Before taking IRESSA, tell your healthcare provider about all of your medical conditions, including if you:. Have lung or breathing problems. Ever had liver problems. Have vision or eye problems. Are pregnant or plan to become pregnant. IRESSA can harm your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with IRESSA. What are the possible side effects of IRESSA? IRESSA ma...

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IRESSA® (gefitinib) | Information and resources

Print label resize label. There are no contraindications. There are no contraindications for IRESSA. Interstitial Lung Disease (ILD): ILD occurred in patients taking IRESSA. Withhold IRESSA for worsening of respiratory symptoms. Discontinue IRESSA if ILD is confirmed. Hepatotoxicity: Obtain periodic liver function testing. Withhold IRESSA for Grade 2 or higher for alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) elevations. Discontinue for severe hepatic impairment. Stay informed ab...

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IRESSA® (gefitinib)

Indication and Limitation of Use. For US Healthcare Professionals. Go to Patient Site. Indication and Limitation of Use. Ordering and Patient Access. IRESSA is indicated for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations as detected by an FDA-approved test. Ocular disorders [keratitis (0.1%), corneal erosion and aberrant eyelash growth (0.2...Bullo...

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