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Dr James P Howard

jamesphoward.com - a junior doctor in London

http://www.jamesphoward.com/

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James Howard

29 I●●●●Road

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Liv●●●ool , Merseyside, L23 4UE

United Kingdom

0784●●●●4459
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Dr James P Howard | jamesphoward.com Reviews
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jamesphoward.com - a junior doctor in London
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Dr James P Howard | jamesphoward.com Reviews

https://jamesphoward.com

jamesphoward.com - a junior doctor in London

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1

FMCalc

http://www.jamesphoward.com/fmcalc.htm

New in version 1.1. Cardiac output (Fick model). Is a free medical calculator for Windows Phone 7. It is not only free in regards to price, but free of ads. Currently, it is the ONLY free medical calculator app on the WP7 OS. Version 1.0 supports 40 calculations/criteria, including:. Corrected QT ( QTc. Hunt and Hess classification. TIMI risk score (STEMI). TIMI risk score (NSTEMI/UA). Thanks to Dan Walters for the wonderful icons.

2

Dr James P Howard

http://www.jamesphoward.com/r.fcgi

Cardiology trainee in London. I'm a NIHR Academic clinical fellow. In cardiology at Imperial College London. Some of my key publications are listed below; others are visible on my Google Scholar profile. R - a quick guide. This is a quick guide to performing common statistical tests and expressions in R. Basic stats - R. A series e.g. SD of a series -. Converting an odds ratio to a probability -. OR / (1 OR). Binomials - coin flip experiments. Variance of a binomial. SD of a binomial. Dbinom(1,5,0.5).

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LINKS TO THIS WEBSITE

cardiologytrials.org cardiologytrials.org

Heart failure trials - CardiologyTrials.org

http://www.cardiologytrials.org/hf

Explaining the most important trials in cardiology. Evidence for heart failure therapies. Improve symptoms in CCF ( CONSENSUS. And reduce mortality even in asymptomatic patients with low ejection fraction ( SOLVD. Also appear to share these benefits ( CHARM. Though any benefit when added to ACEi is controversial ( CHARM. Do confer extra benefit when added to ACEi/ARBs in NYHA 3 ( RALES. And NYHA 2 CCF ( EMPHASIS-HF. Also improve mortality and reduce hospitalisations ( CIBIS-II. If blockers such as.

cardiologytrials.org cardiologytrials.org

ISIS-2 TRIAL - CardiologyTrials.org

http://www.cardiologytrials.org/detail/22

Explaining the most important trials in cardiology. Multicenter, double-blinded, two-by-two factorial, randomized, placebo-controlled trial. Streptokinase OR Aspirin OR Both. Suspected acute MI within 24 hours of symptom onset. No clear indication for, or contraindication to, streptokinase or aspirin. History of GI bleed or PUD. Allergy to streptokinase or aspirin. 10 years (in most recent paper). Vascular mortality at 5 weeks. Randomized by 2x2 factorial design. Aspirin vs. placebo (oral for 1 month).

cardiologytrials.org cardiologytrials.org

EPHESUS TRIAL - CardiologyTrials.org

http://www.cardiologytrials.org/detail/55

Explaining the most important trials in cardiology. Patients in whom the following criteria were met were eligible for randomization 3 to 14 days after acute myocardial infarction:. Acute myocardial infarction as documented according to standard criteria. Heart failure as documented by the presence of pulmonary rales, chest radiography showing pulmonary venous congestion, or the presence of a third heart sound. Use of potassium-sparing diuretics. Time to death from any cause. Death from cardiovascular ca...

cardiologytrials.org cardiologytrials.org

Hypertension trials - CardiologyTrials.org

http://www.cardiologytrials.org/htn

Explaining the most important trials in cardiology. Evidence for hypertension therapies. Pharmacological therapy for hypertension has been shown to reduce mortality, and many trials use stroke as an outcome. Most patients require multiple agents for good control ( ALLHAT. ACEi) seem to reduce stroke in patients 'not classically' hypertensive ( PROGRESS. ARB) appear superior to beta-blockers for reducing mortality, even with similar blood pressure reductions ( LIFE. Though end-points were similar for.

cardiologytrials.org cardiologytrials.org

PLATO TRIAL - CardiologyTrials.org

http://www.cardiologytrials.org/detail/27

Explaining the most important trials in cardiology. 18624 ACS -STEMI, 24hrs after symptoms. Major exclusion criteria were any contraindication against the use of clopidogrel, fibrinolytic therapy within 24 hours before randomization, a need for oral anticoagulation therapy, an increased risk of bradycardia, and concomitant therapy with a strong cytochrome P-450 3A inhibitor or inducer. Composite of death from vascular causes, MI or stroke. Ticagrelor superior to clopidogrel in ACS, including mortality.

cardiologytrials.org cardiologytrials.org

GISSI-3 TRIAL - CardiologyTrials.org

http://www.cardiologytrials.org/detail/83

Explaining the most important trials in cardiology. AMI and preserved LVEF. Multicenter, open label, 2x2 factorial design, randomized trial. Lisinopril OR GTN (IV- PO) OR both. Typical chest pain accompanied by ST changes, either:. 1mm ST elevation or depression in â 1 limb leads. 2mm ST elevation or depression in â 1 chest leads. Admitted to CCU within 24h of symptom onset. Severe CHF requiring any of study drugs. Contraindications to study drugs:. History of bilateral renal artery stenosis.

cardiologytrials.org cardiologytrials.org

ISIS-1 TRIAL - CardiologyTrials.org

http://www.cardiologytrials.org/detail/21

Explaining the most important trials in cardiology. Atenolol (IV, then oral). Suspected MI thought to be within 12 hours of the onset of symptoms. Already on verapamil or beta-blockers. Bradycardia, heart block. Combined end-point of death, arrest, or reinfarction. Atenolol given within first 24 hours improved mortality (controversial, unblinded, see COMMITT trial). Lancet. 1986 Jul 12;2(8498):57-66. Significant reduction in vascular mortality in treatment week and at 1 year. Designed by Dr James P Howard.

cardiologytrials.org cardiologytrials.org

Cardiac surgery trials - CardiologyTrials.org

http://www.cardiologytrials.org/surgery

Explaining the most important trials in cardiology. Evidence for cardiac surgery. 2-3 VD (vs. PCI). LMS/3VD (vs. PCI). MV disease in DM. T2DM - vs OMT and PCI. Designed by Dr James P Howard. And maintained by Dr Chris J Bond.

cardiologytrials.org cardiologytrials.org

Atrial fibrillation (AF) trials - CardiologyTrials.org

http://www.cardiologytrials.org/af

Explaining the most important trials in cardiology. Evidence for atrial fibrillation (AF) therapies. And may be superior in elderly or co-morbid patients ( AFFIRM. Strict rate control may provide no further benefits ( RACE-II. Is beneficial even in rhythm control ( AFFIRM. Aspirin is sufficient in low-risk patients ( SPAF. But anti-thrombotic agents are necessary in high risk patients ( SPAF-II. Newer agents such as apixiban ( ARISTOTLE. And dabigatran ( RE-LY. May reduce stroke and/or bleeding.

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Cardiology trainee in London. I'm a NIHR Academic clinical fellow. In cardiology at Imperial College London. Some of my key publications are listed below; others are visible on my Google Scholar profile. Finally, I'm an amateur yet avid programmer and Pythonista. Some of my source code is available here on my GibHub. Quantifying the 3 Biases. Circulation: Cardiovascular Quality and Outcomes. Other articles covering our meta-analysis include Forbes' article. And the Motley Fool. After CONVERGE and Symplic...

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