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non-covalent mass spectrometry | AK Morgner

Our research area is the analysis of non-covalent protein complexes with ESI- and LILBID-mass spectrometry. LILBID is a new method for the soft transfer of biological samples into the gas phase for mass spectrometric analysis. ESI is a more traditional method, which we use for ion-mobility measurements as well

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Uni Frankfurt Inst f theo u phys Chemie

Nina Morgner

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Fra●●●urt , 60433

DE

49.6●●●●9429
mo●●●●●@chemie.uni-frankfurt.de

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non-covalent mass spectrometry | AK Morgner | lilbid.com Reviews
<META>
DESCRIPTION
Our research area is the analysis of non-covalent protein complexes with ESI- and LILBID-mass spectrometry. LILBID is a new method for the soft transfer of biological samples into the gas phase for mass spectrometric analysis. ESI is a more traditional method, which we use for ion-mobility measurements as well
<META>
KEYWORDS
1 Massenspektrometrie
2 nicht-kovalent
3 native
4 mass spectrometry
5 protein
6 complex
7 non-covalent
8 non covalent
9 MS
10 new method
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Page content here
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ak morgner,non covalent mass spectrometry,sample menu,people,research,non covalent complexes,mass spectrometry methods,lilbid,nesi,publications,teaching,analysis software mass,open positions
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non-covalent mass spectrometry | AK Morgner | lilbid.com Reviews

https://lilbid.com

Our research area is the analysis of non-covalent protein complexes with ESI- and LILBID-mass spectrometry. LILBID is a new method for the soft transfer of biological samples into the gas phase for mass spectrometric analysis. ESI is a more traditional method, which we use for ion-mobility measurements as well

INTERNAL PAGES

lilbid.com lilbid.com
1

AK Morgner

http://www.lilbid.com/people.html

ERC starting grant holder. Email: morgner (at) chemie.uni-frankfurt.de. Phone: 49 69 798-29441. Email: J.Hoffmann (at) chemie.uni-frankfurt.de. Phone: 49 69 798-29282. Email: hellwig (at) chemie.uni-frankfurt.de. Phone: 49 69 798-29282. Email: lieblein (at) chemie.uni-frankfurt.de. Phone: 49 69 798-. At) chemie.uni-frankfurt.de. Phone: 49 69 798-29282. At) chemie.uni-frankfurt.de. Phone: 49 69 798-29587. Email: VuHuu (at) chemie.uni-frankfurt.de. Phone: 49 69 798-29587. Phone: 49 69 798-29587.

2

AK Morgner

http://www.lilbid.com/mass_spectrometry.html

Mass spectrometry (MS) methods are well suited for the investigation of gas phase ions, due to the inherent sensitivity and resolution of MS. The critical point in the analysis of non-covalently linked complexes is their transfer from solution into the gas phase, while keeping the complexes intact. Both are soft methods, allowing for complexes to be transferred intact into the gas phase. Template design by Andreas Viklund.

3

AK Morgner

http://www.lilbid.com//index.html

Welcome to the Morgner group. We are located at the Institute of Physical and Theoretical Chemistry at the Goethe University Frankfurt. Our research interest lies in the investigation of non-covalently bound complexes using mass spectrometry methods. A second aspect is the further development of a new mass spectrometry method, which can complement existing methods: LILBID (Laser Induced Liquid Bead Ion Desorption). Template design by Andreas Viklund.

4

AK Morgner

http://www.lilbid.com/LILBID.html

Microdroplets (50 μm diameter) of the sample solution are introduced into vacuum with the help of an. On demand droplet generator. There they are irradiated one by one by a mid-IR laser which runs at the same frequency (10Hz). Template design by Andreas Viklund.

5

AK Morgner

http://www.lilbid.com/non-covalent_complexes.html

Non-covalent bonds between biomolecules (such as proteins or nucleic acids) are critical in maintaining the three-dimensional structure of large molecular complexes - the little machines that perform most of the cruicial functions in a cell. Many regulating mechanisms function via non-covalent interactions between these biomolecules or with specific ligands. Understanding these interactions is a vital part of understanding the biomolecular complexes as a functional unit. Template design by Andreas Viklund.

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