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Sep 2014 - Melissa is awarded an ACS Research Scholars Grant. Aug 2014 - Kathy defends her Ph.D. thesis and graduates! Aug 2014 - Melissa is awarded an NIH grant. Jun 2014 - Pedro defends his Ph.D. thesis and graduates! May 2014 - Melissa receives an AHA grant. Jan 2014 - Nori receives the Dean's Award for Postdoctoral Research Excellence. Jan 2014 - Kathy is named an HHMI-UCI Graduate Fellow. Oct 2013 - Nori wins "Best Talk" at the Southern California Eukaryotic Pathogens Symposium. Oct 2012 - Kathy pre...

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Sep 2014 - Melissa is awarded an ACS Research Scholars Grant. Aug 2014 - Kathy defends her Ph.D. thesis and graduates! Aug 2014 - Melissa is awarded an NIH grant. Jun 2014 - Pedro defends his Ph.D. thesis and graduates! May 2014 - Melissa receives an AHA grant. Jan 2014 - Nori receives the Dean's Award for Postdoctoral Research Excellence. Jan 2014 - Kathy is named an HHMI-UCI Graduate Fellow. Oct 2013 - Nori wins Best Talk at the Southern California Eukaryotic Pathogens Symposium. Oct 2012 - Kathy pre...

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2 research

3 people

4 publications

5 photo gallery

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8 toxoplasma gondii

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Home | lodoenlab.bio.uci.edu Reviews

https://lodoenlab.bio.uci.edu

Sep 2014 - Melissa is awarded an ACS Research Scholars Grant. Aug 2014 - Kathy defends her Ph.D. thesis and graduates! Aug 2014 - Melissa is awarded an NIH grant. Jun 2014 - Pedro defends his Ph.D. thesis and graduates! May 2014 - Melissa receives an AHA grant. Jan 2014 - Nori receives the Dean's Award for Postdoctoral Research Excellence. Jan 2014 - Kathy is named an HHMI-UCI Graduate Fellow. Oct 2013 - Nori wins "Best Talk" at the Southern California Eukaryotic Pathogens Symposium. Oct 2012 - Kathy pre...

INTERNAL PAGES

lodoenlab.bio.uci.edu

1

Lodoen Lab Research

http://lodoenlab.bio.uci.edu/styled-3/index.html

1 Innate immune responses to. Although adaptive, cell-mediated immunity has long been known to be critical for controlling. Infection, it is now appreciated that innate immune recognition and effector functions also play an important role in host defense against the parasite. We are working to identify host cell pathways that contribute to early recognition of. By human peripheral blood monocytes and to define the parasite factors involved in these processes. (At right, an intracellular rosette of. Macro...

2

Lodoen Lab People

http://lodoenlab.bio.uci.edu/styled/index.html

BA, Dartmouth College. A Karimzadeh, N Ueno, and MB Lodoen. Human innate Immunity to. Is Mediated by Host Caspase-1 and ASC and Parasite GRA15. 4: e00255-13. 2013. Tirotta, E, P Duncker, J Oak, S Klaus, MR Tsukamoto,. And TE Lane. Epstein-Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis. 253: 110-6. 2013. Hashimi, ST, JA Fulcher, MH Chang,. 114: 404-14. 2009. BS, California Lutheran University. Epub ahead of print].

3

Photo Gallery

http://lodoenlab.bio.uci.edu/styled-4/index.html

Woods Hole Immunoparasitology Meeting (April 2013). Kathy, Melissa, and Lanny. UCI Undergraduate Research Opportunities Program (UROP) Symposium (May 2013). Datta presents his research. End-of-the-Year Lab BBQ in Newport Beach (June 2013). A Zoolander moment: Melissa, Lanny, Pedro, Kathy, Elyse, Nori, Alborz, and Datta. Southern California Eukaryotic Pathogens Symposium (Oct 2013). Nori (L) with Keynote Speaker Dr. Scott Dawson. 2013 Lodoen Lab Contact Me.

4

Lodoen Lab Publications

http://lodoenlab.bio.uci.edu/styled-2/index.html

Morgado, P, DM Sudarshana, L Gov, KS, Harker, T Lam, P Casali, JP Boyle, and MB Lodoen. Induction of CD40 on Infected Macrophages Enhances Interleukin-12 Responses. 82: 4047-55. 2014. Shastri, AJ, ND Marino, M Franco, MB Lodoen, and JC Boothroyd. GRA25 is a novel virulence factor of. And influences the host immune response. 82: 2595-605. 2014. Harker, KS, E Jivan, FY McWhorter, WF Liu, and MB Lodoen. Tachyzoite motility on vascular endothelium. 5: e01111-13. 2014. Epub ahead of print, Nov. 18, 2013].

5

Contact

http://lodoenlab.bio.uci.edu/styled-6/index.html

Melissa Lodoen, Ph.D. University of California, Irvine. Department of Molecular Biology and Biochemistry. Irvine, CA 92697. 2013 Lodoen Lab Contact Me.

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toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: Parasite manipulation of the invariant chain (Ii/CD74) and the peptide editor H2-DM affects MHC-II antigen presentation during Toxoplasma gondii infection

http://toxoplasmaparasite.blogspot.com/2015/07/parasite-manipulation-of-invariant.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, July 22, 2015. Parasite manipulation of the invariant chain (Ii/CD74) and the peptide editor H2-DM affects MHC-II antigen presentation during Toxoplasma gondii infection. 2015 Jul 20. pii: IAI.00415-15. [Epub ahead of print]. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom). Features the latest news regarding this protozoan parasite, including information about releva...

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: May 2015

http://toxoplasmaparasite.blogspot.com/2015_05_01_archive.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, May 27, 2015. Prime-Boost Vaccination with Toxoplasma Lysate Antigen, but Not with a Mixture of Recombinant Protein Antigens, Leads to Reduction of Brain Cyst Formation. 2015 May 26;10(5):e0126334. doi: 10.1371/journal.pone.0126334. Infection with the ubiquitous parasite Toxoplasma gondii is a threat for immunocompromised patients and pregnant women and effective immune-prophylaxis is still lacking. 2015 May 21...

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: August 2015

http://toxoplasmaparasite.blogspot.com/2015_08_01_archive.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, August 26, 2015. Guanabenz repurposed as an anti-parasitic with activity against acute and latent toxoplasmosis. 2015 Aug 24. pii: AAC.01683-15. [Epub ahead of print]. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Effect of parasitic infection on dopamine biosynthesis in dopaminergic cells. Apicomplexa; Dopa decarboxylase; Manipulation; Neurotransmitter; Tyrosine hydroxylase. Posted by THE 'SCOPE.

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: Immunity against chronic toxoplasmosis in mice induced by recombinant rhoptry proteins encapsulated in poly (lactide-co-glycolide) microparticles

http://toxoplasmaparasite.blogspot.com/2015/08/immunity-against-chronic-toxoplasmosis.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Friday, August 07, 2015. Immunity against chronic toxoplasmosis in mice induced by recombinant rhoptry proteins encapsulated in poly (lactide-co-glycolide) microparticles. 2015 Aug 6. [Epub ahead of print]. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom). Subscribe To This Blog. Toxo Links and Labs. Awesome Inc. template. Powered by Blogger.

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: The Effect of Latent Toxoplasma gondii Infection on the Immune Response in HIV-Infected Patients

http://toxoplasmaparasite.blogspot.com/2015/08/the-effect-of-latent-toxoplasma-gondii.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Saturday, August 08, 2015. The Effect of Latent Toxoplasma gondii Infection on the Immune Response in HIV-Infected Patients. 2015;2015:271842. doi: 10.1155/2015/271842. Epub 2015 Jul 12. PubMed - in process]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom). Subscribe To This Blog. Toxo Links and Labs. Awesome Inc. template. Powered by Blogger.

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: Nitric oxide stimulates early egress of Toxoplasma gondii tachyzoites from Human foreskin fibroblast cells

http://toxoplasmaparasite.blogspot.com/2015/08/nitric-oxide-stimulates-early-egress-of.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Thursday, August 13, 2015. Nitric oxide stimulates early egress of Toxoplasma gondii tachyzoites from Human foreskin fibroblast cells. 2015 Aug 13;8:420. doi: 10.1186/s13071-015-1037-5. T gondii tachyzoites were cultured in human foreskin fibroblast (HFF) cells and were then treated with NO released by sodium nitroferricyanide (III) dihydrate (SNP). The egressed parasites were analysed by flow cytometry.

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: Alternative splicing mechanisms orchestrating post-transcriptional gene expression: intron retention and the intron-rich genome of apicomplexan parasites

http://toxoplasmaparasite.blogspot.com/2015/07/alternative-splicing-mechanisms.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, July 22, 2015. Alternative splicing mechanisms orchestrating post-transcriptional gene expression: intron retention and the intron-rich genome of apicomplexan parasites. 2015 Jul 21. [Epub ahead of print]. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom). Subscribe To This Blog. Toxo Links and Labs. Awesome Inc. template. Powered by Blogger.

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii

http://toxoplasmaparasite.blogspot.com/2015/08/rabgdi-is-negative-regulator-of.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, August 05, 2015. RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii. Proc Natl Acad Sci U S A. 2015 Aug 3. pii: 201510031. [Epub ahead of print]. IFN-γ–inducible GTPase; Toxoplasma gondii; cell-autonomous immunity; negative regulation. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom).

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages

http://toxoplasmaparasite.blogspot.com/2015/07/pyrimidinergic-receptor-activation.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, July 22, 2015. Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages. 2015 Jul 20;10(7):e0133502. doi: 10.1371/journal.pone.0133502. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom). Subscribe To This Blog. Toxo Links and Labs. Awesome Inc. template. Powered by Blogger.

toxoplasmaparasite.blogspot.com

The Toxoplasma Blog: The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii

http://toxoplasmaparasite.blogspot.com/2015/07/the-orphan-nuclear-receptor-tlx-is.html

Up to date information and news regarding the protozoan parasite Toxoplasma gondii. Wednesday, July 22, 2015. The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii. 2015 Jul 21;13(7):e1002200. doi: 10.1371/journal.pbio.1002200. eCollection 2015. PubMed - as supplied by publisher]. Posted by THE 'SCOPE. Subscribe to: Post Comments (Atom). Subscribe To This Blog. Toxo Links and Labs. Awesome Inc. template. Powered by Blogger.

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Sep 2014 - Melissa is awarded an ACS Research Scholars Grant. Aug 2014 - Kathy defends her Ph.D. thesis and graduates! Aug 2014 - Melissa is awarded an NIH grant. Jun 2014 - Pedro defends his Ph.D. thesis and graduates! May 2014 - Melissa receives an AHA grant. Jan 2014 - Nori receives the Dean's Award for Postdoctoral Research Excellence. Jan 2014 - Kathy is named an HHMI-UCI Graduate Fellow. Oct 2013 - Nori wins "Best Talk" at the Southern California Eukaryotic Pathogens Symposium. Oct 2012 - Kathy pre...

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