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Welcome to the Luca Lab. We are interested in understanding the genetic and molecular basis of inter-individual and inter-population differences in complex phenotypes. We combine evolutionary and functional genomics approaches to study intermediate phenotypes (e.g.: transcription factor binding, gene expression, protein secretion, etc.) and how they are affected by gene-environment interactions. 540 E Canfield St. Detroit, MI 48201. Header image: Detroit Skyline. Center for Molecular Medicine and Genetics.

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Welcome to the Luca Lab. We are interested in understanding the genetic and molecular basis of inter-individual and inter-population differences in complex phenotypes. We combine evolutionary and functional genomics approaches to study intermediate phenotypes (e.g.: transcription factor binding, gene expression, protein secretion, etc.) and how they are affected by gene-environment interactions. 540 E Canfield St. Detroit, MI 48201. Header image: Detroit Skyline. Center for Molecular Medicine and Genetics.

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HOME | lucalab.wayne.edu Reviews

https://lucalab.wayne.edu

Welcome to the Luca Lab. We are interested in understanding the genetic and molecular basis of inter-individual and inter-population differences in complex phenotypes. We combine evolutionary and functional genomics approaches to study intermediate phenotypes (e.g.: transcription factor binding, gene expression, protein secretion, etc.) and how they are affected by gene-environment interactions. 540 E Canfield St. Detroit, MI 48201. Header image: Detroit Skyline. Center for Molecular Medicine and Genetics.

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heejungshim.org

PEOPLE – Heejung Shim Lab

https://heejungshim.org/people

We seek highly motivated students to join our group. We are based in the Department of Statistics. At the Purdue University. Please feel free to contact Heejung Shim. If you are interested in joining us or having a rotation. The Great Ocean Road, 2014. I am an Assistant Professor in the Department of Statistics. At the Purdue University. I completed my BS in Mathematics (with a double major in Computer Science and Engineering) from the POSTECH. Advised by Dr. Bret Larget. I received a B.S. in mat...I lik...

heejungshim.org

Meetings – Heejung Shim Lab

https://heejungshim.org/meetings

Deep Learning Journal Club. Phylogenetics/Stochastic Processes Journal Club. 1/09/2017 Welcome to Israa and Yash. Israa and Yash joined us this semester and will develop the software for probabilistic splicing models. 6/29/2016 "BayesCAT: Bayesian Co-estimation of Alignment and Tree" has been accepted at Biometrics. 6/26/2016 We have been organizing two journal clubs with other labs: deep learning JC. And Phylogenetics/Stochastic Processes Journal Club. 6/7/2016 riboHMM paper is now out in eLife [ link.

heejungshim.org

Publications – Heejung Shim Lab

https://heejungshim.org/publications

I E Schor, J. F. Degner, D. Harnett, E. Cannavo, F. P. Casale, H. Shim. D Garfield, E. Birney, M. Stephens, O. Stegle, E. E. Furlong, Promoter shape varies across populations and affects promoter evolution and expression noise, Nature Genetics, 2017, February 13, doi:10.1038/ng.3791. And B Larget, BayesCAT: Bayesian Co-estimation of Alignment and Tree, Biometrics. 2017 Jan 18. doi: 10.1111/biom.12640. A Raj*, S. Wang*, H. Shim*. A Raj*, H. Shim*. L M Mangravite, B. E. Engelhardt, M. W. Me...H Chun*, C&#4...

heejungshim.org

Software – Heejung Shim Lab

https://heejungshim.org/software

Shim lab github page. And Heejung’s github page. An R package for Bayesian multi-scale models. E Pantaleo and M. Stephens, Bayesian multi-scale models for detecting differences in high-throughput sequencing data between multiple groups and their applications in small sample sizes, in prep. A software package for wavelet-based genetic association analyses of high-throughput sequencing data. A software package for multivariate association analyses. S Keles. Mixture modeling for genome-wide localization...

heejungshim.org

COURSES – Heejung Shim Lab

https://heejungshim.org/courses

Spring 2017: Applied Regression Analysis (STAT 512). Spring 2016: Applied Regression Analysis (STAT 512). 1/09/2017 Welcome to Israa and Yash. Israa and Yash joined us this semester and will develop the software for probabilistic splicing models. 6/29/2016 "BayesCAT: Bayesian Co-estimation of Alignment and Tree" has been accepted at Biometrics. 6/26/2016 We have been organizing two journal clubs with other labs: deep learning JC. And Phylogenetics/Stochastic Processes Journal Club. And clustering gene ex...

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Welcome to the Luca Lab. We are interested in understanding the genetic and molecular basis of inter-individual and inter-population differences in complex phenotypes. We combine evolutionary and functional genomics approaches to study intermediate phenotypes (e.g.: transcription factor binding, gene expression, protein secretion, etc.) and how they are affected by gene-environment interactions. 540 E Canfield St. Detroit, MI 48201. Header image: Detroit Skyline. Center for Molecular Medicine and Genetics.

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