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Alzheimer's Disease Research, Small Molecule Programs | Rancho Santa Fe, CA

Help prevent a devastating illness with Alzheimer's disease research and small colecule programs by calling us at (510) 827-1118 in Rancho Santa Fe, CA.

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Alzheimer's Disease Research, Small Molecule Programs | Rancho Santa Fe, CA | maderabio.com Reviews
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Help prevent a devastating illness with Alzheimer's disease research and small colecule programs by calling us at (510) 827-1118 in Rancho Santa Fe, CA.
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Alzheimer's Disease Research, Small Molecule Programs | Rancho Santa Fe, CA | maderabio.com Reviews

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Help prevent a devastating illness with Alzheimer's disease research and small colecule programs by calling us at (510) 827-1118 in Rancho Santa Fe, CA.

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Alzheimer's Disease Research, Small Molecule Programs | Rancho Santa Fe, CA

http://www.maderabio.com/alzheimer-s-prevention.html

About 30% of Alzheimer's Disease Cases May Be Prevented Through Lifestyle Modifications (1). All content found on the maderabiosciences.com Website, were created for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. NIH National Institute on Aging web page. Please see the video “. This fo...

2

Small Molecule Development, Compound Identification | Rancho Santa Fe, CA

http://www.maderabio.com/Small-Molecule-Development-Compound-Identification.html

Small Molecule Therapeutics for Alzheimer's. To develop effective, orally bioavailable, small molecule therapeutics to treat Alzheimer's disease in its very early stages modifying the natural course of the disease. Forms of Aβ lead to Aβ-induced neuroinflammation as a key component of Alzheimer’s disease pathology. ApoE function correlates with other neuropathological changes in Alzheimer’s disease some of which are Aβ-independent. Engagement of a novel biological target. Read More About Our Strategy Here.

3

Small Molecule Development, Compound Identification | Rancho Santa Fe, CA

http://www.maderabio.com/Healthy-Aging.html

ApoE2 is Positively Associated with Exceptional Longevity and Decreased Risk of Age-Related Diseases. Exceptional longevity is known to run in families and is due to a combination of factors including maintaining a healthy lifestyle in addition to genetic factors. Studies often define healthy aging as reaching an advanced age, often 85 years old, free of chronic disease. Findings from recent studies implicate several biological pathways that may contribute to the aging process (1). 4) a) Burt, T. D&#...

4

Alzheimer's Disease Research, Small Molecule Programs | Rancho Santa Fe, CA

http://www.maderabio.com/detailed-strategy.html

Madera's Approach to Alzheimer's Therapeutics: Upregulation of Functional ApoE via Small Molecules. Therapeutic Enhancement of Phagocytic Clearance of Beta Amyloid. Madera’s strategy is to focus on the identification and development of orally-available small molecule compounds that penetrate the brain to enhance the clearance of. And interrupt the neuroinflammatory-. Cycle Our strategy is supported by evidence of the central role. ApoE, though its three isoforms (. 4), modulates neuroinflammation via.

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Potentiation of ApoE Function via. Recent studies further support the central role and interplay of amyloid-beta and neuroinflammation in the development of Alzheimer's disease. Our focus is to develop effective, orally bioavailable, small molecule therapeutics to treat Alzheimer's disease. Perhaps 30% of all Alzheimer's cases may be prevented though life style changes. Learn about Madera BioSciences. Read More About Our Business. By Web.com Group, Inc.

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