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MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases

MAKScientific Is Developing Drugs To Treat Disease By Targeting the Endocannabinoid System. MAKScientific is developing drugs to treat a variety of medical disorders by modulating the endocannabinoid system. Our approach involves the selective targeting of known components of this biochemical system which includes the cannabinoid receptors (CB1 and CB2), a number of enzymes (FAAH, NAAA, DGL and MGL) and the cannabinoid transporter system. MAKScientific has a large and growing portfolio of small molecule mod

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MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases | makscientific.com Reviews
<META>
DESCRIPTION
MAKScientific Is Developing Drugs To Treat Disease By Targeting the Endocannabinoid System. MAKScientific is developing drugs to treat a variety of medical disorders by modulating the endocannabinoid system. Our approach involves the selective targeting of known components of this biochemical system which includes the cannabinoid receptors (CB1 and CB2), a number of enzymes (FAAH, NAAA, DGL and MGL) and the cannabinoid transporter system. MAKScientific has a large and growing portfolio of small molecule mod
<META>
KEYWORDS
1 Cannabinoid
2 Cannabinoid receptors
3 CB1
4 CB2
5 CB1 receptor
6 CB2 receptor
7 Fatty acid
8 amide hydrolase
9 FAAH
10 Monoacylglyceral lipase
CONTENT
Page content here
KEYWORDS ON
PAGE
drug pipeline,about us,makscientific snapshot,download this pdf,intellectual property,media center,legal
CONTENT-TYPE
utf-8
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MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases | makscientific.com Reviews

https://makscientific.com

MAKScientific Is Developing Drugs To Treat Disease By Targeting the Endocannabinoid System. MAKScientific is developing drugs to treat a variety of medical disorders by modulating the endocannabinoid system. Our approach involves the selective targeting of known components of this biochemical system which includes the cannabinoid receptors (CB1 and CB2), a number of enzymes (FAAH, NAAA, DGL and MGL) and the cannabinoid transporter system. MAKScientific has a large and growing portfolio of small molecule mod

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MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases

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MAKScientific Is Developing Drugs To Treat Disease By Targeting the Endocannabinoid System. MAKScientific is developing a pipeline of small molecule modulators that target key intervention points in the endocannabinoid system. A lead pre-clinical drug candidate (AM6545) is a peripherally restricted CB1 receptor neutral antagonist in advanced pre-clinical testing for treating chronic liver disease and metabolic disorders. For a company summary and contact information.

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MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases

http://www.makscientific.com/media_center.html

September 12, 2012. MAKScientific will attend the BioPharm America 2012. Conference to be held September 19-21, 2012 in. Boston, MA USA. The conference fosters international biotechnology partnering and licensing opportunities. August 21, 2012. March 29, 2012. Professor and Co-founder Alexandros Makriyannis honored for his contributions to medicinal chemistry by the American Chemical Society. Click here for details. March 14, 2012. About the University of Connecticut.

3

MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases

http://www.makscientific.com/about_us.html

MAKScientific will be a leading therapeutic company that brings new and innovative drugs to the market place for human diseases that can be modulated by the endocannabinoid system. Chairman. CEO, Stonington Partners, LLC, former President and CEO Weiss Peck and Greer, former Chairman Merrill Lynch Banks. PhD, President and CEO Mersana Therapeutics, formerly President and CEO, Aton Pharmaceuticals, former President/CSO OSI Pharmaceuticals. Harry H. Penner. Alex Makriyannis, Ph.D. 1996 First to develop ame...

4

MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases

http://www.makscientific.com/intellectual_property.html

A large portfolio of patent applications covering the compounds described has already been filed with several patents issued or granted. Our lead CB1 neutral antagonist (AM6545) and several backup compounds have been described in PCT/US2009/001054. Additional CB1 receptor antagonists have been disclosed in PCT/US2006/000720 and PCT/US2008/007257. PO Box 188, Watertown, MA 02471 Laboratories at Boston University Medical Center, Boston, MA.

5

MAKScientific | Discovering Medications for Metabolic Disorders, Pain, Addiction, and Neurological Diseases

http://www.makscientific.com/drug_pipeline.html

MAKScientific is a recognized leader in endocannabinoid research and drug development. The Company is developing a pipeline of orally available small molecule drugs that target important intervention points in the endocannabinoid system. These targets include the known cannabinoid receptors (CB1 and CB2) as well as key enzymes involved in modulating the system including fatty acid amide hydrolase (FAAH), monoacylglyceral lipase (MGL), N-acylethanolamine-hydrolyzing amidase (NAAA), diacylglycerol ...

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