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Marco Mangone lab
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Bioinformatics Tools | Mangone Lab

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Genetics and Genomics in C. elegans. Apaome: a platform for 3'UTR biology in C. elegans. The 3'UTRome is an open-access database that provides a rich and comprehensive resource for 3'UTR biology in C. elegans. 3'UTRs are important portions of mRNAs required for post-transcriptional regulation by interacting with proteins or non-coding RNAs (e.g. microRNAs). To study the role of 3'UTRs we are building a 3'UTR database for C. elegans. Access: www.APAome.org.

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Join | Mangone Lab

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Genetics and Genomics in C. elegans. Individuals seeking a post-doctoral position:. Applicants for wet bench science must have:. A PhD in biology or related field. Expertise in C. elegans biology is mandatory. Expertise in molecular biology and biochemistry. Experience in handling high-throughput experiments is desirable. Applicants for dry bench science must have:. A PhD in bioinformatics, computational biology or related field. Fluent with Perl and other programming languages such as Java, Phyton, etc.

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Lab events | Mangone Lab

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Genetics and Genomics in C. elegans. 2013-08-02 21.19.03.jpeg. Marco Mangone - The Biodesign Institute - 727 E. Tyler St. Marco Mangone, Biodesign institute at Arizona State University, 727 E. Tyler St. Tempe, AX 85287.

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Publications | Mangone Lab

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Genetics and Genomics in C. elegans. Before arrival at ASU. Hutchins ED, Eckalbar WL, Wolter JM, Mangone M. And Kusumi K (2016). Differential expression of conserved and novel microRNAs during tail regeneration in the lizard A. BMC Genomics 2016 17:339. Wallace R, Twomey LC, Custard MA, Monya N, Cummins PM, Mangone M. And Murphy RP (2016). Potential Diagnostic and Prognostic Biomarkers of Epigenetic Drift within the Cardiovascular Compartment. Kotagama K, Babb C, Wolter JM, Murphy RP, Mangone M. Marco Ma...

5

Protocols | Mangone Lab

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Genetics and Genomics in C. elegans. Luminescent Identification of Functional Elements in 3'UTRs: 3'LIFE. The 3'LIFE is adapted from the well-characterized dual luciferase reporter assay, and performed in high-throughput (HT). 3'LIFE rapidly identifies functional targets of a given miRNA in a panel of thousands of test 3'UTRs in co-transfection experiments. 3'LIFE uses two specially designed vectors to express the test 3'UTRs (pLIFE-3'UTR) and the miRNA (pLIFE-miRNA). ORDER THE 3'-LIFE VECTORS HERE.

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Main | Mangone Lab

Genetics and Genomics in C. elegans. Welcome to the Mangone Lab @ Arizona State University. Bull; One of the fundamental questions in molecular biology is how genes and the modulation of their expression are able to produce life in such incredible variety. Bull; The mRNA molecule is the key intermediate of this process. That in turn control gene expression at a post-transcriptional level. Bull; The long-term goal of our laboratory is to highlight these fundamental biological mechanisms. Graduate student)...

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