manninglab.org

The Manning Lab

Research on Kinases, Genomics, Evolution and the grand mysteries of biology. April 11, 2017. Mark's epic definition and analysis of the phosphatome, across 9 eukaryotic species, is now the cover article. We're looking for a postdoc. To work on cancer mutation analysis, and have contract position open for a computational research associate. Mark and Gerard have made substantial updates to the Phosphatome website. Mark's phosphatome paper is under review at Science Signaling. Evolution of cell death. The R...

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Gerard Manning

10564 Cor●●●●●●●●●n Del Mar

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Gerard Manning

10564 Cor●●●●●●●●●n Del Mar

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Gerard Manning

10564 Cor●●●●●●●●●n Del Mar

San●●●ego , California, 92130

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The Manning Lab | manninglab.org Reviews

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Research on Kinases, Genomics, Evolution and the grand mysteries of biology. April 11, 2017. Mark's epic definition and analysis of the phosphatome, across 9 eukaryotic species, is now the cover article. We're looking for a postdoc. To work on cancer mutation analysis, and have contract position open for a computational research associate. Mark and Gerard have made substantial updates to the Phosphatome website. Mark's phosphatome paper is under review at Science Signaling. Evolution of cell death. The R...

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1 research

2 publications

3 lab members

4 the manning lab

5 news and events

6 phosphatome paper published

7 at science signaling

8 hiring

9 phosphatome updates

10 and wiki

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The Manning Lab | manninglab.org Reviews

https://manninglab.org

Research on Kinases, Genomics, Evolution and the grand mysteries of biology. April 11, 2017. Mark's epic definition and analysis of the phosphatome, across 9 eukaryotic species, is now the cover article. We're looking for a postdoc. To work on cancer mutation analysis, and have contract position open for a computational research associate. Mark and Gerard have made substantial updates to the Phosphatome website. Mark's phosphatome paper is under review at Science Signaling. Evolution of cell death. The R...

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manninglab.org

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Manning Lab: Members

http://www.manninglab.org/about.html

About the Manning Lab. We are a bioinformatics/genomics research group, based at the Salk Institute, near San Diego, California. We work on the genomics and evolution of protein kinases and phosphatases, and on more general questions of evolution of gene families, paritcularly in building accurate gene models for eukaryotes, and in orthology. Our kinase focus comes from Gerard's days at Sugen. We maintain a number of websites to report our research and assist the broader community.

2

Manning Lab Publications

http://www.manninglab.org/publications.html

Newton K, Manning G. 85:743-63. doi: 10.1146/annurev-biochem-060815-014830. PubMed. Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2. Foster SA, Whalen DM, Özen A, Wongchenko MJ, Yin J, Yen I, Schaefer G, Mayfield JD, Chmielecki J, Stephens PJ, Albacker LA, Yan Y, Song K, Hatzivassiliou G, Eigenbrot C, Yu C, Shaw AS, Manning G, Skelton NJ, Hymowitz SG, Malek S. 29(4):477-93. doi: 10.1016/j.ccell.2016.02.010. PubMed. Proc Natl Acad Sci U S A. ACS Med Chem Lett. Holliday GL, Bai...

3

The Manning Lab

http://www.manninglab.org/index.html

Research on Kinases, Genomics, Evolution and the grand mysteries of biology. Kinase Evolution in Arthropods. As part of the centipede genome publication. In PLoS Biology, Galina Erickson compared dozens of athropod kinomes and found extensive kinase loss across several arthropod lineages. Oct 25, 2014. Multiple functions of HSF1. Worm lifespan and the proteosome. We supported the Dillin lab. In a Nature paper. Showing the role of a proteasome subunit in proteostasis and longevity in worms. April 5, 2012.

4

Manning Lab: Members

http://www.manninglab.org/members.html

Manages the lab and the Razavi Newman Center for Bioinformatics at Salk. Strong interest in providing innovative solutions to practical problems in bioinformatics, and a particular passion for understanding what genomics can tell us about evolution and biological functions. Builds the pipelines that drive most of our work in kinomes, evolution, and proteostasis. Maintainer of kinase.com. And other lab websites. Kinase evolution in arthopods and other metazoan lineages. Evolution of kinases in many lineag...

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Research on Kinases, Genomics, Evolution and the grand mysteries of biology. April 11, 2017. Mark's epic definition and analysis of the phosphatome, across 9 eukaryotic species, is now the cover article. We're looking for a postdoc. To work on cancer mutation analysis, and have contract position open for a computational research associate. Mark and Gerard have made substantial updates to the Phosphatome website. Mark's phosphatome paper is under review at Science Signaling. Evolution of cell death. The R...

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