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Basics of Extract Manufacture | Extractopedia

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Skip to main content. Basics of Extract Manufacture. Basics of Extract Manufacture. The manufacture of an. Extraction is the process by which water soluble proteins and other bioactive molecules are removed from the allergenic source material and held in solution. The extraction process utilizes a series of quality-controlled methods to help avoid contamination and promote product. The standardization process requires that all manufacturers perform additional testing with an FDA-approved laboratory metho...

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Selecting Allergen Extracts | Extractopedia

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Skip to main content. Choosing which allergenic extracts to use in your practice can be both fun and challenging. There are many factors to consider depending on whether you are designing a diagnostic panel for skin testing, selecting the most representative allergens for treatment, or even just figuring out how to order the products and store them properly. Sterile empty vials, syringes, testing devices, and skin test control solutions just to name a few. And we will add more helpful hints to these pages.

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Importance of Cross-Reactivity | Extractopedia

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Skip to main content. Species often exhibit some degree of. In general, plant species within the same taxonomic family may be substantially, though not completely,. Additionally, there are several allergenic proteins which are common across unrelated species known as pan-allergens . For some patients, these proteins can generate an. Immune response and contribute to broad cross-reactivity profiles including the occurrence of certain food allergies. Latin Names and Major Allergens. Use of Allergen Extracts.

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Potency Labeling | Extractopedia

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Skip to main content. The biologic strength (potency) of an. Can be expressed in a variety of ways. In general, all allergenic extracts are divided into 2 categories:. The FDA has mandated standardization testing for a limited number of extracts. The purpose of standardization is to minimize the amount of variability between lots and manufacturers of the same extract. Within each of these categories,. Concentration is a variable that can provide additional information about an extract's potency.

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Stay Updated | Extractopedia

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Skip to main content. Latest news on allergy. New information and site updates. Practice tools and resources. Basics of Extract Manufacture. Stability and Expiration Dating. Use of Allergen Extracts.

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Topics | Extractopedia

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Skip to main content. Thank you for visiting the first online tool dedicated to allergenic extracts. This site is provided to all physicians, physician assistants, nurses, and health practitioners who use allergenic extracts for allergy skin testing and. Click here for an important announcement regarding Special Mixes. Find the answer and improve your knowledge. Basics of Extract Manufacture. Stability and Expiration Dating. Use of Allergen Extracts. Basics of Extract Manufacture. Use of Allergen Extracts.

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Glossary | Extractopedia

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Skip to main content. The glossary contains definitions and explanations of industry-specific and scientific terminology used within Extractopedia. Click one of the letters above to find terms beginning with that letter. Basics of Extract Manufacture. Stability and Expiration Dating. Use of Allergen Extracts.

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References | Extractopedia

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Skip to main content. General References used throughout:. Cox, L, et al. Immunotherapy: a practice parameter third update. J Allergy Clin Immunol. 2011 Mar;127(3):840. Cox, L, et al. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol. 2007;127(suppl):S25-85, IV. Li, JT, et al. Allergen immunotherapy: a practice parameter. Ann Allergy. Immunol. 2003;90:1-40. Nelson, M. 2009. Physician’s Instruction Guide for the Preparation of Allergen Extract. Dilution, temp, preservative:.

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Introduction | Extractopedia

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Skip to main content. Click on the Table of Contents and find the topic that interests you. You can also enter a word or phrase into the search box, hit enter and a treasure trove of information will come streaming back. What are your peers exploring? Click on the home page and select one of the top 5 searches. Extractopedia is your website and your resource. From the home page you can click on Suggest a Topic to email us your ideas for other information that should be included on the site. Additionally,...

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Quality Parameters | Extractopedia

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Skip to main content. During manufacture, the quality control (QC) of allergenic extracts presents a variety of challenges. One important consideration is the expected variability that is inherent with naturally derived source materials. Allergenic extracts exhibit a certain degree of lot-to-lot variability that cannot be avoided. However, if the extract manufacturing steps are well controlled this allows each supplier to deliver products that have a reasonable level of. Quality Concern - Color Variation.