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MARASCOLAB.ORG

Marasco Lab

The Marasco Laboratory is making major scientific advances in the treatment of emerging infectious diseases and cancer at Dana-Farber Cancer Institute.

http://www.marascolab.org/

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Dana-Farber Cancer Institute

Dave Rothfarb

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US

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he●●●●●●●●●●●●●●●●●●@dfci.harvard.edu

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Dana-Farber Cancer Institute

Dave Rothfarb

450 Br●●●●●●ne Ave

Bo●●on , MA, 02215

US

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he●●●●●●●●●●●●●●●●●●@dfci.harvard.edu

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Marasco Lab | marascolab.org Reviews
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The Marasco Laboratory is making major scientific advances in the treatment of emerging infectious diseases and cancer at Dana-Farber Cancer Institute.
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1 Marasco Lab
2 Marasco Laboratory
3 Wayne Marasco
4 Wayn Marasco
5 marasco
6 merasco
7 dr. wayne marasco
8 wayne marasco md
9 wayne marasco phd
10 emerging infectious diseases
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Marasco Lab | marascolab.org Reviews

https://marascolab.org

The Marasco Laboratory is making major scientific advances in the treatment of emerging infectious diseases and cancer at Dana-Farber Cancer Institute.

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marascolab.org marascolab.org
1

Current News

http://www.marascolab.org/index.php/news/current-news

Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model. Suarez ER, Chang DK, Sun J, Sui J, Freeman GJ, Signoretti S, Zhu Q, Marasco WA. Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model. Oncotarget. 2016 Apr 29. PMID: 27145284. MAbs 2016 Mar 10:1-12. PMID: 26963739. Sci Rep. 2016 Feb 16;6:20842. PMID: 26880249. Anti-CCR4 antibody enha...

2

Announcements

http://www.marascolab.org/index.php/news/announcements

August 4, 2016. Access to primary tissue for humanized mouse studies. The Marasco Lab has recently been approved to collect matched PBMCs and tumor tissues from renal cell carcinoma patients that are undergoing therapeutic nephrectomy! This is the second cancer, in addition to ovarian cancer, that we will have access to primary tissue for our. Humanized mouse studies that will examine monoclonal antibodies and CAR T cells. Feb 3, 2012. Humanized Mouse Program open to research community. June 6, 2011.

3

Opportunities

http://www.marascolab.org/index.php/opportunities

Working in Dr. Marasco's laboratory provides exposure to the most recent developments in the field of antibody engineering, humanized mouse models. And adult stem cell biology. We are always looking for highly motivated post-doctoral fellows and graduate students to join our research team, particularly those individuals with high intellect who are also creative thinkers. Wayne A. Marasco, M.D., Ph.D. Department of Cancer Immunology and AIDS. Boston, MA 02215. Excellent communication and teamwork skills.

4

Chief

http://www.marascolab.org/index.php/labpersonnel/chief

Wayne A. Marasco, M.D., Ph.D., Chief. Professor, Dept of Cancer Immunology and AIDS. Professor of Medicine, Department of Medicine. Associate Physician, Division of Infectious Diseases, Dept of Medicine. Brigham and Women's Hospital. Board of Distinguished Advisors, The Antibody Society. Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it. For use in regenerative medicine and adult stem cell research. Which can be delivered to cells by gene transfer techniq...

5

Scientific focus and achievements

http://www.marascolab.org/index.php/about/scientific-focus-and-achievments

Core technologies and resources. Core technologies and resources. Scientific focus and achievements. Our National Foundation of Cancer Research (NFCR) Center for Therapeutic Antibody Engineering (CTAE). At Dana-Farber Cancer Institute is working in a broad range of discovery and translational research in cancer. We have the tools, know-how and expertise to advance our novel immunotherapy discoveries from bench to bedside. We have a major effort in constructing and improving humanized mice. Site developed...

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humanized-mice.org humanized-mice.org

Humanized Mouse Program - Our Published Studies

http://www.humanized-mice.org/index.php/mouse-model/marasco-studies

Studies in the Marasco Laboratory with these mouse models include:. Hong Chang, Subhabrata Biswas, Aimee St. Clair Tallarico, Phuong Thi Nguyen Sarkis, Shusheng Geng, Madhura M. Panditrao, Quan Zhu and Wayne A. Marasco. Human B-cell ontogeny in humanized NOD/SCID gcnull mice generates a diverse yet auto/poly- and HIV-1 reactive antibody repertoire. Genes and Immunity. 13, 399-410 (July/August 2012) doi:10.1038/gene.2012.16. PMID:22592523. Genes were amplified, cognate V. Abstract of talk by Hong Chang.

humanized-mouse.org humanized-mouse.org

Humanized Mouse Program - Our Published Studies

http://www.humanized-mouse.org/index.php/mouse-model/marasco-studies

Studies in the Marasco Laboratory with these mouse models include:. Hong Chang, Subhabrata Biswas, Aimee St. Clair Tallarico, Phuong Thi Nguyen Sarkis, Shusheng Geng, Madhura M. Panditrao, Quan Zhu and Wayne A. Marasco. Human B-cell ontogeny in humanized NOD/SCID gcnull mice generates a diverse yet auto/poly- and HIV-1 reactive antibody repertoire. Genes and Immunity. 13, 399-410 (July/August 2012) doi:10.1038/gene.2012.16. PMID:22592523. Genes were amplified, cognate V. Abstract of talk by Hong Chang.

humanized-mice.org humanized-mice.org

Humanized Mouse Program - Opportunities

http://www.humanized-mice.org/index.php/opportunities

Applicants should have a strong interest in human translational research. Job openings are posted with Human Resources. Interested applicants should send their CV and cover letter to:. Wayne A. Marasco, M.D., Ph.D. Department of Cancer Immunology and AIDS. Boston, MA 02215. Please check for current opportunities at DFCI HR. Click on logos for links to our other sites. Site developed by DF/HCC Health Communication Core.

humanized-mouse.org humanized-mouse.org

Humanized Mouse Program - Review articles

http://www.humanized-mouse.org/index.php/relevant-literature/review-articles

Human immune system development. New generation humanized mice for virus research: Comparative aspects and future prospects. Akkina R.Virology. 2013 Jan 5;435(1):14-28. doi:10.1016/j.virol.2012.10.007. PMID: 23217612. Animal models of antiretroviral prophylaxis for HIV prevention. García-Lerma JG, Heneine W. Curr Opin HIV AIDS. 2012 Nov;7(6):505-13. doi:10.1097/COH.0b013e328358e484. PMID: 22964889. HIV-1 immunopathogenesis in humanized mouse models. Zhang L, Su L. Can Humanized Mice Reflect the Complex P...

humanized-mice.org humanized-mice.org

Humanized Mouse Program - Cost

http://www.humanized-mice.org/index.php/cost

Click on logos for links to our other sites. Site developed by DF/HCC Health Communication Core.

biorestorative.com biorestorative.com

Scientific Advisory Board | BioRestorative Therapies

http://www.biorestorative.com/content/scientific-advisory-board-0

Skip to main content. BioRestorative Therapies' combined Management Team, Board of Directors and Scientific Advisory Board members have extensive experience in the healthcare industry. Together we have expert experience in the stem cell science, medical-related services, life science services marketing, public company business management and financing, IP development and licensing, business acquisitions, and strategic partnering. Chief Medical Advisor for Spine Medicine. Gregory Lutz, M.D. Dr Cavagnaro’s...

humanized-mouse.org humanized-mouse.org

Humanized Mouse Program - Human immune system development

http://www.humanized-mouse.org/index.php/relevant-literature/human-immune-system-development

Human immune system development. Human immune system development. Systemic Human T Cell Developmental Processes in Humanized Mice Cotransplanted With Human Fetal Thymus/Liver Tissue and Hematopoietic Stem Cells. Joo SY, Chung YS, Choi B, Kim M, Kim JH, Jun TG, Chang J, Sprent J, Surh CD, Joh JW, Kim SJ. Transplantation. 2012 Dec 15;94(11):1095-1102. PMID: 23222735. J Immunol. 2012 Dec 1;189(11):5223-9. doi: 10.4049/jimmunol.1201789. Epub 2012 Oct 22. PMID: 23089398. IL-15 transpresentation promotes both ...

humanized-mouse.org humanized-mouse.org

Humanized Mouse Program - FAQ

http://www.humanized-mouse.org/index.php/mouse-model/faq

1 What is the extent of human immune-reconstitution in the different humanized mice models? 2 Do these mice develop characteristic lymphoid follicles in secondary lymphoid tissues? 3 Is the reconstructed human immune system functional in these mice? Click on logos for links to our other sites. Site developed by DF/HCC Health Communication Core.

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April 29, 2015. HCoV-HKU1 Spike protein usues O-acetylated sialic acid as an attachment receptor determinant and emplys HE protein as a receptor-destroying enzyme. Effects of human anti-spike protein receptor binding domain antibodies on SARS coronavirus neutralization escape and fitness. June 26, 2014. Prolonged expression of an anti-HIV-1 gp120 minibody to the female rhesus macaque lower genital tract by AAV gene transfer. Launch of Humanized Mouse Program. Marasco Lab Humanized Mouse Program. Rare VH-...

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