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MCC950 Small Molecule Inhibitor - Avistron Chemistry Products and Services
MCC950 is a potent, selective and orally available inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. MCC950 is a highly potent specific NLRP3. Inhibitor with demonstrated in vivo activity in multiple NLRP3-dependent mouse models. And in ex vivo samples from individuals with Cryopyrin-Associated Periodic Syndrome (CAPS). MCC950, previously known as CRID3. J Pharmacol Exp Ther. 2001 Oct;299(1):187-97. Potent and Specific NLRP3 inhibitor- IC50 7 nM in human or mouse macrophages.
