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March 20, 2007. Fosamax – Generic Fosamax – Alendronate. 8212; Administrator @ 3:42 pm. Fosamax – Fosamax Side Effects – Fosamax Information. Pharmacology: Alendronate is a bisphosphonate that acts as a potent, specific inhibitor of osteoclast-mediated bone resorption. Bisphosphonates are synthetic analogs of pyrophosphate that bind to the hydroxyapatite found in bone. Bioavailability was negligible whether alendronate was administered with or up to 2 hours after a standardized breakfast. Concomitant...

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