methioninase.com

Recombinant L-Methionine-gamma-Lyase

AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA. Telephone: (858)654-2555; E-mail: all@anticancer.com. Mercaptomethane lyase, L-methionine-. Lyase (METase) is a pyridoxal phosphate- containing enzyme which degrades L-methionine to. Ketobutyrate, ammonia and methyl mercaptan. Lyase(rMETase) has been shown to be a broad-bases tumor-selective chemotherapy agent and has synergetic effects with traditional chemotherapy [1-8]. Lyase (rMETase) is cloned from.

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Recombinant L-Methionine-gamma-Lyase | methioninase.com Reviews

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AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA. Telephone: (858)654-2555; E-mail: all@anticancer.com. Mercaptomethane lyase, L-methionine-. Lyase (METase) is a pyridoxal phosphate- containing enzyme which degrades L-methionine to. Ketobutyrate, ammonia and methyl mercaptan. Lyase(rMETase) has been shown to be a broad-bases tumor-selective chemotherapy agent and has synergetic effects with traditional chemotherapy [1-8]. Lyase (rMETase) is cloned from.

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Recombinant L-Methionine-gamma-Lyase | methioninase.com Reviews

https://methioninase.com

AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA. Telephone: (858)654-2555; E-mail: all@anticancer.com. Mercaptomethane lyase, L-methionine-. Lyase (METase) is a pyridoxal phosphate- containing enzyme which degrades L-methionine to. Ketobutyrate, ammonia and methyl mercaptan. Lyase(rMETase) has been shown to be a broad-bases tumor-selective chemotherapy agent and has synergetic effects with traditional chemotherapy [1-8]. Lyase (rMETase) is cloned from.

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Methioninase

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AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA. Telephone: (858)654-2555; E-mail: all@anticancer.com. Mercaptomethane lyase, L-methionine-. Lyase (METase) is a pyridoxal phosphate- containing enzyme which degrades L-methionine to. Ketobutyrate, ammonia and methyl mercaptan. Lyase(rMETase) has been shown to be a broad-bases tumor-selective chemotherapy agent and has synergetic effects with traditional chemotherapy [1-8]. Lyase (rMETase) is cloned from.

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Patents&Paublications

http://www.methioninase.com/Publications

AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA. Telephone: (858)654-2555; E-mail: all@anticancer.com. US Patent Nos. 6,231,854; 5,888,506; 5,690.929; 5,891,704; 7,329,516; 8,465,734; 7,799,549. Japan Patent No. 2,930,723. Europe Patent Nos. 668,933; 1,287,830. Australia Patent No. 687,768. Canada Patent No. 2,149,776. China Patent Nos. ZL200480017595.6; ZL200580015792.9. 1 Hoffman, R.M., Jacobsen, S.J., and Erbe, R.W. Reversion to methionine independence in. Expression and Purification 12.

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Homocysteine Assay

http://www.methioninase.com/Antitumor

RMETase is a selective-anti-tumor agent. Figure 1. Efficacy of rMETase on growth of human colon tumors. HCT 15 and HT 29 in nude mice. RMETase (5 or 10 units/g every 8 h) was administered by i.p. injection in nude mice with human colon tumor HCT 15. Growing s.c. The efficacy was evaluated by tumor weight. Figure 2. Antitumor efficacy of rMETase in combination with 5-FU. Against Lewis lung carcinoma. And survival rate (. RMETase , 5-FU , combination of rMETase and 5-FU (.

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Methioninase Background

http://www.methioninase.com/Background

Lyase (METase) is a homotetrameric pyridoxal-5. Phosphate (PLP) enzyme with a molecular weight of 172 kd. One sub-unit of METase comprises of 398 amino acids with a molecular weight of 43 kd. Biochemical and Physiological Actions. RMETase degrades methionine and other sulfur-containing amino acids, such as homocysteine and cysteine, which are major intermedials in the methylation process and related to cancer and other diseases.

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MetaMouse

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INDEX of AntiCancer websites:. INDEX of AntiCancer websites:. NOVEL DRUGS AND INDICATIONS. Introduction to AntiCancer Inc. The pioneer of the MetaMouse. AntiCancer Inc. is the foremost pre-clinical cancer contract research organization and has been in business since 1984. AntiCancer offers orthotopic proteins [ click here MetaMouse. The AntiCancer team of twenty scientists is lead by Robert M. Hoffman, a world-leading cancer researcher [ click here for Dr. Hoffman’s CV. What we can do for you:. Help you ...

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AntiCancer Products

http://www.anticancer.com/AntiCancer%20Products.htm

1 Preclinical contract research. Nude mice expressing fluorescent proteins. Cell lines expressing fluorescent proteins. Histoculture Drug Response Assay (HDRA). 5 Enzymatic Homocysteine assay. 6 Enzymatic Vitamin B6 assay. 7 Enzymatic Cysteine assay.

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methioninase.com

Recombinant L-Methionine-gamma-Lyase

AntiCancer, Inc. 7917 Ostrow Street, San Diego, CA 92111 USA. Telephone: (858)654-2555; E-mail: all@anticancer.com. Mercaptomethane lyase, L-methionine-. Lyase (METase) is a pyridoxal phosphate- containing enzyme which degrades L-methionine to. Ketobutyrate, ammonia and methyl mercaptan. Lyase(rMETase) has been shown to be a broad-bases tumor-selective chemotherapy agent and has synergetic effects with traditional chemotherapy [1-8]. Lyase (rMETase) is cloned from.

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