mikelove.wordpress.com
Binomial GLM for ratios of read counts – Mike Love’s blog
https://mikelove.wordpress.com/2013/09/02/binomial-glm-for-ratios-of-read-counts
Mike Love’s blog. Binomial GLM for ratios of read counts. For certain sequencing experiments (e.g. methylation data), one might end up with a ratio of read counts at a certain location satisfying a given property (e.g. ‘is methylated’) and want to test if this ratio is significantly associated with a given variable, x. Here is a bit of code for using the glm() function in R with the binomial distribution with weights representing the covering reads. September 2, 2013. Leave a Reply Cancel reply. Postdoct...
mikelove.wordpress.com
Jacob and Monod – Mike Love’s blog
https://mikelove.wordpress.com/2013/09/08/jacob-and-monod
Mike Love’s blog. The original gene regulation diagram? J Mol Biol. 1961 Jun;3:318-56. Genetic regulatory mechanisms in the synthesis of proteins. JACOB F, MONOD J. September 8, 2013. 2 thoughts on “Jacob and Monod”. October 6, 2013 at 3:55 pm. Do you take questions? I don’t think it’s poisson since I’m not counting mutations over time or space it’s just the number of mutations at one point in time. Any guidance is appreciated. November 7, 2013 at 11:42 am. Leave a Reply Cancel reply. Postdoctoral Fellow...
mikelove.wordpress.com
How to check your simple definition of p-value – Mike Love’s blog
https://mikelove.wordpress.com/2014/10/16/how-to-check-your-simple-definition-of-p-value
Mike Love’s blog. How to check your simple definition of p-value. I just read Andrew Gelman’s post about an article with his name on it starting with an inaccurate definition of p-value. I sympathize with all parties. Journalists and editors are just trying to reduce technical terms by presenting layperson definitions. Earlier this year I caught a similar inaccurate definition. A simple rule for testing if your definition is wrong:. P-value is the probability that a result is due to random chance. Where ...
mikelove.wordpress.com
Empirical Bayes and the James-Stein rule – Mike Love’s blog
https://mikelove.wordpress.com/2013/11/07/empirical-bayes
Mike Love’s blog. Empirical Bayes and the James-Stein rule. Suppose we observe 300 individual estimates. Now if we assume. The James-Stein rule gives an estimator for. Below is code for a little RStudio script to see how changing the balance of variance between data y and the variance of the means changes the amount of optimal shrinkage. For more info, read the paper referenced below! It uses the RStudio’s manipulate library: info on that. November 7, 2013. November 19, 2013. November 19, 2013 at 4:09 pm.
support.bioconductor.org
User: Michael Love
https://support.bioconductor.org/u/5822
Diams; 9.5k. 3 years, 7 months ago. M* * * * * * * * @gmail.com. I'm an Assistant Professor in the Department of Biostatistics at UNC Chapel Hill. My main Bioconductor involvement is to maintain these software packages:. Posts by Michael Love. Prev • 1,725 results • page 1 of 173 •. Answer: A: Using tximport to read in data from sailfish experiment. Can you run traceback() after the error and report the output? Written 9 hours ago by Michael Love. Diams; 9.5k. Comment: C: DESeq2 coefficient of variation.
mikelove.wordpress.com
Plot hclust with colored labels – Mike Love’s blog
https://mikelove.wordpress.com/2013/10/16/plot-hclust-with-colored-labels
Mike Love’s blog. Plot hclust with colored labels. Again I find myself trying to plot a cluster dendrogram with colored labels. With some insight from this post. I came up with the following function:. October 16, 2013. October 16, 2013. 1 thought on “Plot hclust with colored labels”. November 22, 2013 at 8:51 am. Or just, ColorDendrogram from sparcl package. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). Get every ...
simplystatistics.org
Courses · Simply Statistics
http://simplystatistics.org/courses
Follow us on twitter @simplystats. A statistics blog by Rafa Irizarry, Roger Peng, and Jeff Leek. The authors of this blog have created a large number of massive online open courses that are always available for you to take online. Data Science Specialization on Coursera. This is a series of 9 classes that teach the entire data science process. The classes were built by Jeff Leek. You can sign up through Coursera. Data analysis for life sciences. Genomic Data Science Specialization on Coursera.
mikelove.wordpress.com
Plotting hclust – Mike Love’s blog
https://mikelove.wordpress.com/2012/08/08/plotting-hclust
Mike Love’s blog. After many years I’ve finally worked out the x and y coordinates of the points in plot.hclust. Hang - 0.07 hc - hclust(dist) plot(hc) pt.heights - c(hc$height[hc$merge[,1] 0],hc$height[hc$merge[,2] 0])[order(-1 * c(hc$merge[,1][hc$merge[,1] 0],hc$merge[,2][hc$merge[,2] 0]) ] points(1:length(hc$order), pt.heights[hc$order] - hang). August 8, 2012. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). Get e...
mikelove.wordpress.com
Points and line ranges – Mike Love’s blog
https://mikelove.wordpress.com/2013/01/13/points-and-line-ranges
Mike Love’s blog. Points and line ranges. Two ways of plotting a grid of points and line ranges. I’m coming around to ggplot2. I recommend skimming the first few chapters of the book to understand what is going on – but it only takes about 30 min or so to understand enough to make basic plots. January 13, 2013. January 17, 2013. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). Notify me of new comments via email.
mikelove.wordpress.com
More hclust madness – Mike Love’s blog
https://mikelove.wordpress.com/2013/10/24/more-hclust-madness
Mike Love’s blog. X - replicate(10,sample(0:1,100,TRUE) library(gplots) hc - hclust(dist(t(x) ) y - sweep(x,2,2 (ncol(x)-order(hc$order) ,*) z - x[order(rowSums(y) ,] heatmap.2(z, trace=none, key=FALSE, Rowv=FALSE,labRow=FALSE, Colv=as.dendrogram(hc), dendrogram=column, scale=none,col=c(grey,blue), lwid=c(2,10). October 24, 2013. October 24, 2013. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). Points and line ranges.
SOCIAL ENGAGEMENT