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Professor of Institute for Medical Engineering and Science. Harvard-MIT Division of Health Sciences and Technology. Massachusetts Institute of Technology. 77 Massachusetts Ave., E25-526C. Cambridge, MA 02139. Admin Asst.: Sean Clarke. Email: clarke 1@mit.edu. Protein Knots knots.mit.edu. Specificity Determining Residue Prediction http:/ tamm.mit.edu/SDR/. Hi-C data analysis library https:/ bitbucket.org/mirnylab/hiclib. Bioinformatics and Integrated Genomics. Physical Sciences in Oncology.

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Mirnylab - Home | mirnylab.mit.edu Reviews

https://mirnylab.mit.edu

Professor of Institute for Medical Engineering and Science. Harvard-MIT Division of Health Sciences and Technology. Massachusetts Institute of Technology. 77 Massachusetts Ave., E25-526C. Cambridge, MA 02139. Admin Asst.: Sean Clarke. Email: clarke 1@mit.edu. Protein Knots knots.mit.edu. Specificity Determining Residue Prediction http:/ tamm.mit.edu/SDR/. Hi-C data analysis library https:/ bitbucket.org/mirnylab/hiclib. Bioinformatics and Integrated Genomics. Physical Sciences in Oncology.

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1

Mirnylab - Publications

http://mirnylab.mit.edu/publications.html

Click here for a complete list of publications. Single-cell Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition. Flyamer I, Gassler J, Imakaev M, Brandão H, Ulianov S, Abdennur N, Razin S, Mirny M, Tachibana-Konwalski K. The 4D Nucleome Project. Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Ritland JC, Shendure J, Zhong S and the 4D Nucleome Network. Cohesin dependent compaction of mitotic chromosomes. Schalbetter SA, Golobor...

2

Mirnylab - Home

http://mirnylab.mit.edu/index.html

Three dimensional organization of chromosomes. Evolutionary Dynamics of Cancer. 2017-03-01: bioRxiv 4D Nucleome Channel. 2017-02-14: Single Nucleus Hi-C paper accepted in Nature! 2017-02-13: Welcome back to MirnyLab, Carino! 2017-02-12: Congratulations to Hugo on receiving a Student Reseach Achievement Award at the Biophysical Society Meeting in New Orleans for his work on Bacterial SMCs.

3

Mirnylab - People

http://mirnylab.mit.edu/people.html

Professor of Medical Engineering and Science, and Physics. Institute for Medical Engineering and Science, and Department of Physics, Massachusetts Institute of Technology. Associate Member of the Broad Institute. Associate Member of the Dana-Farber Cancer Institute. Junior Fellow, Harvard Society of Fellows. PhD, Harvard Biophysics. MSc Chemistry, Weizmann Institute of Science. Biosketch @ MIT Computational and Systems Biology. Biosketch @ MIT Physics. Univeristy of Tübingen, Ph.D. My research interests ...

4

PSOC

http://mirnylab.mit.edu/PSOC.html

The impact of deleterious passenger mutations on cancer progression. A) Evolutionary model of cancer progression by accumulation of driver and passenger mutations. Drivers arrive infrequently, but have a significant beneficial effect (measured by s. While passengers arise frequently and have a small deleterious effects ( s. B) Example simulations of cancer progression in our model. McFarland CD, Korolev KS, Kryukov GV, Sunyaev S, Mirny LA. PNAS 2013 110(7);. Importance of 3D proximity for SCNA formation.

5

Mirnylab - Courses

http://mirnylab.mit.edu/courses.html

HST452J: Statistical Physics in Biology. Mehran Karar, Leonid Mirny. HSTA01: Freshman Seminar in Quantitative Biology. HST508/Biophysics 170: Quantitative Genomics. Leonid Mirny, Shamil Sunyaev, Gregory Kryukov. First meeting of the class September 12, see course calendar.

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Faculty | MIT Center for the Physics of Living Systems

https://mitbiophysics.wordpress.com/faculty

MIT Center for the Physics of Living Systems. The research of the Benedek group centers on phase transitions, self-assembly and aggregation of several biological molecules. Prof Chakraborty’s work is focused on developing and applying statistical mechanical methods that can complement biological experiments and clinical data to understand how the adaptive immune system works, and then harness this knowledge to devise vaccines against scourges like HIV. Ibrahim I. Cissé. Photo credit: Matt Staley, HHMI).

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Faculty | Physical Sciences-Oncology Center

http://psoc.northwestern.edu/people/faculty

Chemistry of Life Processes Institute. Ionic modulation of chromatin in cancer. Biochemistry and Molecular Genetics. Molecular modulation of chromatin and nuclear structure in cancer. Biochemistry/ Mol. Pharmacol. Univ Mass. Med. School. Lucy A. Godley. Mechanics of nuclei, chromosomes and chromatin in cancer. Molecular Bioscience/ Physics and Astronomy. Health Sciences Technology/ Physics. Cell and Molecular Biology. Education and Outreach Unit. Chemistry of Life Processes Institute. PDX Human Tumor Core.

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UW Genome Sciences: GS Seminars

http://www.gs.washington.edu/news/seminars.htm

Each year, the UW Department of Genome Sciences brings the world’s leading researchers from a broad spectrum of scientific areas to campus to discuss latest advances in genetics, genomics, proteomics, computational research and related emerging tools and technologies. All Genome Sciences Seminars take place at 3:30 on Wednesdays in Foege Auditorium unless otherwise noted. The new GS Seminars mailing list is: gs-seminars [ a. Please follow this link for a listing of past seminars. Monday, August 29. Walte...

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Mirnylab - Home

Professor of Institute for Medical Engineering and Science. Harvard-MIT Division of Health Sciences and Technology. Massachusetts Institute of Technology. 77 Massachusetts Ave., E25-526C. Cambridge, MA 02139. Admin Asst.: Sean Clarke. Email: clarke 1@mit.edu. Protein Knots knots.mit.edu. Specificity Determining Residue Prediction http:/ tamm.mit.edu/SDR/. Hi-C data analysis library https:/ bitbucket.org/mirnylab/hiclib. Bioinformatics and Integrated Genomics. Physical Sciences in Oncology.

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MirnySCREEN's blog - Coucou :3 - Skyrock.com

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