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NIH Molecular Libraries-Small Molecule Repository

NIH Molecular Libraries Small Molecule Repository collects samples for high throughput biological screening and distributes them to the NIH Molecular Libraries Probe Production Centers Network. Learn more. MLSMR is a key component of the Molecular Libraries Initiative. Project supporting New Pathways to Discovery. Century. The project is funded in whole with Federal funds from the National Institutes of Health. Department of Health and Human Services, under Contract No. HHS-N-278-2004-41001C.

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NIH Molecular Libraries-Small Molecule Repository | mlsmr.evotec.com Reviews
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NIH Molecular Libraries Small Molecule Repository collects samples for high throughput biological screening and distributes them to the NIH Molecular Libraries Probe Production Centers Network. Learn more. MLSMR is a key component of the Molecular Libraries Initiative. Project supporting New Pathways to Discovery. Century. The project is funded in whole with Federal funds from the National Institutes of Health. Department of Health and Human Services, under Contract No. HHS-N-278-2004-41001C.
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1 a roadmap initiative
2 mlsmr project
3 compound identification
4 quality control
5 sample storage
6 sample arrays
7 informatics
8 mlpcn centers
9 mlsmr contacts
10 submit compounds
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NIH Molecular Libraries-Small Molecule Repository | mlsmr.evotec.com Reviews

https://mlsmr.evotec.com

NIH Molecular Libraries Small Molecule Repository collects samples for high throughput biological screening and distributes them to the NIH Molecular Libraries Probe Production Centers Network. Learn more. MLSMR is a key component of the Molecular Libraries Initiative. Project supporting New Pathways to Discovery. Century. The project is funded in whole with Federal funds from the National Institutes of Health. Department of Health and Human Services, under Contract No. HHS-N-278-2004-41001C.

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1

NIH Molecular Libraries-Small Molecule Repository

http://mlsmr.evotec.com/MLSMR_HomePage/centers.html

New Mexico Molecular Libraries Screening Center. University of New Mexico School of Medicine. 900 Camino de Salud, NE. Albuquerque, New Mexico 87131-5636. Principal Investigator: Professor Larry Sklar. Http:/ screening.health.unm.edu/. NIH Chemical Genomics Center (NCGC). National Institutes of Health. Bethesda, MD 20892. Principal Investigator: Christopher P. Austin, Director, NIH Chemical Genomics Center. Http:/ www.ncgc.nih.gov/. San Diego Chemical Library Screening Center. 10901 N Torrey Pines Road.

2

NIH Molecular Libraries-Small Molecule Repository

http://mlsmr.evotec.com/MLSMR_HomePage/arrays.html

MLSMR uses aliquots of the Working Store solution in DMSO to create microtiter plates for delivery to the MLPCN. The screening centers choose from a range of delivery options including 96-, 384-, or 1536-well SBS plate formats. The current compound quota is 450 nanomoles per screening center per year. Not including material for hit follow-up. MLSMR delivers the full repository collection. For standard screening to each center up to twice per year.

3

NIH Molecular Libraries-Small Molecule Repository

http://mlsmr.evotec.com/MLSMR_HomePage/identify.html

Appropriate for the NIH Molecular Libraries Probe Production Center Network collection by evaluating and selecting from commercial, academic, and government suppliers. We group compounds into four classes:. SS) comprising known bioactives such as drugs, toxins, metabolites, and others. NP) and derivatives from known and documented natural sources. TL) subcategorized into protease, kinase, GPCR, ion channel, and nuclear receptor sets. DC) all other compounds available for purchase or acquisition.

4

NIH Molecular Libraries-Small Molecule Repository

http://mlsmr.evotec.com/MLSMR_HomePage/index.html

NIH Molecular Libraries Small Molecule Repository collects samples for high throughput biological screening and distributes them to the NIH Molecular Libraries Probe Production Centers Network. Learn more. MLSMR is a key component of the Molecular Libraries Initiative. Project supporting New Pathways to Discovery. Century. The project is funded in whole with Federal funds from the National Institutes of Health. Department of Health and Human Services, under Contract No. HHS-N-278-2004-41001C.

5

NIH Molecular Libraries-Small Molecule Repository

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Literature - NIH SMR

http://nihsmr.evotec.com/evotec/literature

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. Literature - NIH SMR. McCarthy A, The NIH Molecular Libraries Program: identifying chemical probes for new medicines. 2010; 17(6):549-50. doi: 10.1016/j.chembiol.2010.06.005. PMID: 20609403. Oprea TI, Bologa CG, Boyer S, Curpan RF, Glen RC, Hopkins AL, Lipinski CA, Marshall GR, Martin YC, Ostopovici-Halip L, Rishton G, Ursu O, Vaz RJ, Waller C, Waldmann H, Sklar LA. A Crowdsourcing Evaluation of the NIH Chemical Probes. Curr Top Med Chem.

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FEEDBACK - NIH SMR

http://nihsmr.evotec.com/evotec/feedback;jsessionid=66546EB21A4B90F97D41B1BD499B4437

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. FEEDBACK - NIH SMR. For any issues and suggestions concerning this webpage please send an email to Evotec (US) Inc. Technical Support. For questions regarding the compound collections please send an email to Evotec (US) Inc. compound management.

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Sets - NIH SMR

http://nihsmr.evotec.com/evotec/sets;jsessionid=66546EB21A4B90F97D41B1BD499B4437

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. Prepared Subsets of the Molecular Libraries Small Molecule Repository. Sets (1 - 1 of. Delivery Plate - 96 wells Greiner 80 well, 2-11 (651201). Product option validation failed. All options are required.

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Cart - NIH SMR

http://nihsmr.evotec.com/evotec/cart;jsessionid=66546EB21A4B90F97D41B1BD499B4437

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. Cart - NIH SMR. Subtotal does not yet include applicable tax or shipping and handling charges.

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Cherry Picks - NIH SMR

http://nihsmr.evotec.com/evotec/cherrypick;jsessionid=66546EB21A4B90F97D41B1BD499B4437

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. Please provide search criteria :. Separated by space or new line and starts with SMR). Separated by space or new line).

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Site Overview Page - NIH SMR

http://nihsmr.evotec.com/evotec/siteoverview

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. Site Overview Page - NIH SMR. From http:/ mli.nih.gov/mli/. The Molecular Libraries Program, a National Center for Advancing Translational Sciences (NCATS) initiative, aims to enhance chemical biology efforts through High Throughput Screening (HTS) to obtain small molecule probes effective at modulating a given biological process or disease state. Http:/ mlsmr.evotec.com/MLSMR HomePage/quality.html. 2Wait 2 days for reply.

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MLSMR Molecular Libraries

http://nihsmr.evotec.com/evotec/;jsessionid=66546EB21A4B90F97D41B1BD499B4437

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. NIH SMR is offering compound subsets for screening by qualified applicants. Learn More. New to NIH SMR? NIH SMR Externalization Program. Evotec (US) Inc. has combined state of the art technology with industry experts to offer compound management services. We help design, build, grow and manage compound collections to the highest quality in support of drug discovery research. How is NCATS advancing translational research?

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Announcements - NIH SMR

http://nihsmr.evotec.com/evotec/announcements

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. Announcements - NIH SMR. Http:/ www.nature.com/. A crowdsourcing evaluation of the NIH chemical probes. Tudor I Oprea, Cristian G Bologa, Scott Boyer, Ramona F Curpan, Robert C Glen, Andrew L Hopkins,. Christopher A Lipinski, Garland R Marshall, Yvonne C Martin, Liliana Ostopovici-Halip, Gilbert Rishton,Oleg Ursu, Roy J Vaz, Chris Waller, Herbert Waldmann and Larry A Sklar. Nat Chem. Biol. 5, 441 447 (2009).

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FAQ - NIH SMR

http://nihsmr.evotec.com/evotec/faq;jsessionid=66546EB21A4B90F97D41B1BD499B4437

NIH Small Molecule Repository. Welcome to the NIH SMR Online Store. FAQ - NIH SMR. 1) How can I order compounds? Please register yourself using the Register Here. Link in the home page. You details will be sent to NIH, upon your approval, you can log into the site using your username and password and order compounds. Last Updated: Jan 21, 2014 05:28PM EST. 2) How long is the turnaround period for my login approval? Last Updated: Jan 21, 2014 05:28PM EST. 3) I forgot my password, how can I get a new one?

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NIH Molecular Libraries-Small Molecule Repository

NIH Molecular Libraries Small Molecule Repository collects samples for high throughput biological screening and distributes them to the NIH Molecular Libraries Probe Production Centers Network. Learn more. MLSMR is a key component of the Molecular Libraries Initiative. Project supporting New Pathways to Discovery. Century. The project is funded in whole with Federal funds from the National Institutes of Health. Department of Health and Human Services, under Contract No. HHS-N-278-2004-41001C.

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