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molres.org

MOLECULAR RESEARCH

Relying upon the team spirit of a scientific partnership, we employ computational and experimental expertise. To explore and explain fundamental chemical and biological phenomena at the molecular level to enhance human knowledge and well-being. They speak of how molecular biology is used in order to find a humans genome. Indeed, every organism is a complex collection of molecules. Our areas of current emphasis are:. Entails the use of computational methods to develop novel bioactive agents that are effec...

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MOLECULAR RESEARCH | molres.org Reviews
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Relying upon the team spirit of a scientific partnership, we employ computational and experimental expertise. To explore and explain fundamental chemical and biological phenomena at the molecular level to enhance human knowledge and well-being. They speak of how molecular biology is used in order to find a humans genome. Indeed, every organism is a complex collection of molecules. Our areas of current emphasis are:. Entails the use of computational methods to develop novel bioactive agents that are effec...
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1 computer aided drug design
2 macromolecular modeling
3 pharmacology
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6 experiments
7 neuroscience
8 astrochemistry and astrobiology
9 coupons
10 reviews
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MOLECULAR RESEARCH | molres.org Reviews

https://molres.org

Relying upon the team spirit of a scientific partnership, we employ computational and experimental expertise. To explore and explain fundamental chemical and biological phenomena at the molecular level to enhance human knowledge and well-being. They speak of how molecular biology is used in order to find a humans genome. Indeed, every organism is a complex collection of molecules. Our areas of current emphasis are:. Entails the use of computational methods to develop novel bioactive agents that are effec...

INTERNAL PAGES

molres.org molres.org
1

MOLECULAR RESEARCH INSTITUTE HOMEPAGE

http://www.molres.org/MRI_Services.html

Interdisciplinary Computer-Aided Design of Bioactive Agents. Experimental Determination of Biological and Pharmacological Activity. Development of Conformational Libraries of Peptides and Flexible Ligand. Development of 3D Pharmacophores for Ligand Receptor Recognition and Activation. Drug Discovery by 3D Database Searching Using 3D Pharmacophores. Lead Optimization by Calculation of Properties Related to Drug Delivery and Enhanced Activity. Construction/Assessment/Use of 3D Models of Target Proteins.

2

MOLECULAR RESEARCH INSTITUTE HOMEPAGE

http://www.molres.org/MRI_Pharm.html

Computer-Aided Design of Bioactive Agents. Pharmacochemical Studies of Opioid Narcotics. Active through August 2004). Molecular Modeling, Design, and Evaluation of BDZ Ligands. Completed in January 2003). Timothy M. DeLorey. We are currently applying this strategy to:. Design of potential treatments for the age-related memory loss associated with senile dementia of the Alzheimer's type. Design of opioid analgesics lacking the side effects of ventilatory depression and physical dependence liability.

3

MOLECULAR RESEARCH INSTITUTE HOMEPAGE

http://www.molres.org/MRI_CADD.html

Pharmacochemical Studies of Opioid Narcotics. Active through August 2004). Molecular Modeling, Design, and Evaluation of BDZ Ligands. Completed in January 2003). Timothy M. DeLorey. Computer-Aided Discovery of Novel Breast Cancer Therapeutics. Completed in June 2002). California Breast Cancer Research Program. Danni L. Harris. Design of GABA(A) Receptor Ligands with Behavioral Selectivity. Studies of Opiate Ligands. Studies of Ligands Inhibiting Breast Cancer Cell Line Growth. What is a receptor?

4

MOLECULAR RESEARCH INSTITUTE HOMEPAGE

http://www.molres.org/MRI_MacroMod.html

Computational Studies of Heme Proteins: P450s and Peroxidases. Theory and Physical Properties and Reactivity in P450s. Completed in January 2003). Danni L. Harris. Theory of Heme Proteins. Completed in September 2002). Danni L. Harris. INDO/CI Studies of Reaction Intermediates. Reaction Pathway Studies in P450s, Thiolate Heme Proteins, and Peroxidases. Construction and Assessment of Models of Mammalian P450s. Assessment of Ligand Binding Modes and Product Distributions of Horseradish and Chloroperoxidase.

5

MOLECULAR RESEARCH INSTITUTE HOMEPAGE

http://www.molres.org/MRI_AstroSci.html

Theoretical Studies of the Extraterrestrial Chemistry of Biogenic Elements and Compounds. Active through April 2006). David E. Woon. Quantum Chemical Studies of Chemistry in the Atmospheres of Titan and Other Outer Solar System Bodies. Active through June 2006). NASA Planetary Atmospheres Program. David E. Woon. Visit The Astrochymist website to read more about astrochemistry.

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Relying upon the team spirit of a scientific partnership, we employ computational and experimental expertise. To explore and explain fundamental chemical and biological phenomena at the molecular level to enhance human knowledge and well-being. They speak of how molecular biology is used in order to find a humans genome. Indeed, every organism is a complex collection of molecules. Our areas of current emphasis are:. Entails the use of computational methods to develop novel bioactive agents that are effec...

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