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Dr. PI's Mtbook, the M. tuberculosis genome in a book
http://mtbook.drpi.ch/index/welcome.html
Genome in a book. To turn a page click on the arrow in the page corner. For a navigation bookmark click on Dr. PI's Mtbook. Contact Dr. PI Bioconsulting. Dr PI's Mtbook, release v. 1.8.0, Jan. 2004. Contact Dr. PI Bioconsulting. Design and Layout 2003-2004 by Paul Imboden, Dr. PI Bioconsulting. Javascripts 2000-2004 by Lutz Slomianka and Paul Imboden. Sequence and annotation based on www.sanger.ac.uk/Projects/M tuberculosis/. Book design based on:. Flurin Spescha, Wie wärs mit etwas Meer?
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Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0047/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Is essential for the de novo synthesis of folate in prokaryotes, lower eukaryotes and in plants. It is absent in mammals. catalizes the formation of dihydropteroate, the immediate precursor of folic acid in the following reaction . 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate 4-aminobenzoate = diphosphate dihydropteroate. Spin / 3D model needs Jmol. The gene is encoded in a In the M. tuberculosis. On the circular M. tuberculosis.
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0026/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Belongs to the cytochrome P450 . These Enyzmes are involved in the oxydative degradation of various compounds. They usually contain a heme that is bound via a cysteine and function as a monooxygenase. catalyses the C14-demethylation of lanosterol . Spin / 3D model needs Jmol. The structural model was obtained from PDB entry , and the description from . Click here to search for at PDB. As the heme axial ligand. On the circular M. tuberculosis. The follow...
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0083/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. DTDP-L-rhamnose is an essential component of the M. tuberculosis. Cell wall. The -gene encodes which is the third enzyme in the dTDP-L-rhamnose pathway. This protein is structurally unique, highly substrate specific and does not require a cofactor, which makes a promising drug target. It catalyses the reaction:. Is a member of the . belongs to the genes responsible for metabolism of sugar nucleotides as shown below. Spin / 3D model needs Jmol. BlueTB mol...
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0066/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Is an oxidorecuctase that catalyses the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate according to the following reaction (dihydrofolatereductase and/or tetrahydrofolate dehydrogenase):. 5,6,7,8-tetrahydrofolate NADP. 7,8-dihydrofolate NADPH H. Spin / 3D model needs Jmol. The structural model was obtained from PDB entry , and the description from . Click here to search for at PDB. The gene is encoded in a In the M. tuberculosis. The foll...
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0015/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Repairs oxidized proteins. Methionine sulfoxide in proteins is reduced to methionine. Its enzyme activity is a oxidoreductase acting on a sulfur group of donors with a disulfide as acceptors . It belongs to the Peptide methionine sulfoxide reductase and is present in most living organisms. Spin / 3D model needs Jmol. The structural model was obtained from PDB entry , and the description from . Click here to search for at PDB. The sequence contains other .
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0016/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Is involved in detoxification. Superoxide is a by-product of aerobic respiration and is produced by oxidative phosphorylation. Superoxide dismutases are ubiquitous metalloproteins that catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. The dismutase enzymes have a very high catalytic efficiency. Spin / 3D model needs Jmol. Three conserved histidins ( 116. Are the probable zink-binding residues. Chromosome lies at .
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0025/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Is involved in nucleotide synthesis and energy metabolism. is ubiquitous and is needed for cell maintenance and cell growth. It belongs to the adenylate kinase . The catalytic activity allows the reversible transfer of the terminal phosphate group from ATP to ADP. ATP AMP = 2 ADP. This 3D-model shows one of the 20 structures in . Spin / 3D model needs Jmol. A AMP-biniding site at position 31-59. And the solvent-exposed LID-Region at position 123-138.
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0056/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Is a oxidoreductase that acts on paired donors and incorporates molecular oxygen . Spin / 3D model needs Jmol. The structural model was obtained from PDB entry , and the description from . Click here to search for at PDB. Is a peptide of with a and a The sequence contains several common plus a cytochrome P450 cysteine heme-iron ligand. As the iron binding heme axial ligand. A putative transmembrane region. And a cell attachment sequence. Whole-genome co...
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0005/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Or dehydroquinase, catalyzes the conversion of 3-dehydroquinate into 3-dehydroshikimate. This is the third step in the shikimate pathway for the biosynthesis of aromatic amino acids from chorismate. The atoms shown in red are deduced from phosphoenolpyruvate that was added in the first step of the . Two classes of dehydroquinases exist, known as types I and II. They are unrelated at the sequence level and they utilize completely different mechanisms.
Mycobacterium tuberculosis molecules by Dr. PI
http://bluetb.drpi.ch/molecule/0090/index.html?structure
Contact Dr. PI. 2005 blueTB, Dr. PI Bioconsulting. Is a protein with unknown function. Based on its amino acid sequence it is a member of the pyridoxamine 5'-phosphate oxidase , whose proteins are flavoproteins that catalyse the oxidation of pyridoxamine-5-phosphate to pyridoxal-5-phosphate. Spin / 3D model needs Jmol. The structural model was obtained from PDB entry , and the description from . Click here to search for at PDB. Another conserved protein of unknown function),. Sequencing project from the ...
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Downhill Mountain Biking Is Awesome 2018 vol. 17. Wednesday, April 4th 2018 - 23:30. AMAZING MTB DOWNHILL SESSION! Saturday, March 31st 2018 - 23:30. Downhill Mountain Biking Is Awesome 2018. Monday, March 26th 2018 - 23:30. Downhill Mountain Biking Is Awesome 2018 Vol.6. Friday, March 23rd 2018 - 00:30. Downhill MTB injury risks are real. Pain vs Reward E1. Friday, March 16th 2018 - 00:30. Page 1 of 3,479. Trenbolone: GREAT DRIVE - seems like your body is not atracted. AMAZING MTB DOWNHILL SESSION!
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MTbook - Datahub Medische Technologie
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