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                                        Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms : Abstract : Nature Reviews Cancer
                                        http://www.nature.com/nrc/journal/v4/n8/abs/nrc1408.html
                                        Jump to main content. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Eugenia E. Calle. The prevalence of obesity is rapidly increasing globally. Epidemiological studies have associated obesity with a range of cancer types, although the mechanisms by which obesity induces or promotes tumorigenesis vary by cancer site. These include insulin resistance and resultant chronic hyperinsulinaemia, increased bioavailability of steroid hormones and localized inflammation&...Guide...