herpesvirus2.blogspot.com
Urinary & Reproductive Infectious Disease: Proposed Vaccination & Eradication
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Monday, April 14, 2008. Proposed Vaccination and Eradication. The current goal of a HSV vaccine is to prevent disease but not infection. Because the ability of HSV to escape the Immune Response (IR), it’s difficult for the host cell to effectively clear infection. Currently, 2 “Phase III trials” (co-sponsored by the National Institute of Allergy and Infectious Diseases and GlaxoSmithKline) has been conducted. The result had showed that an “investigational” vaccine appears to o...In both trials, the vacci...
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Urinary & Reproductive Infectious Disease: Proposed Genomic Evolution
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Monday, April 14, 2008. HSV-2 to HSV-1 genome comparison. The BugSpray comparison below shows genome alignment based on similar genes and dramatically illustrates the similarity of gene arrangement between the HSV-1 and HSV-2 genomes. BugSpray draws lines from genes on the top genome, in this case HSV-2, to the gene with the best BLAST hit in the bottom genome, here HSV-1. Green lines. Indicate pairs of genes that code on the same strand. Indicate gene pairs that code on the opposite strand. Ob=ArticleUR...
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Urinary & Reproductive Infectious Disease: Genome Information
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Monday, April 14, 2008. Herpes simplex virus type 2 has a genome of double stranded DNA which has been reported to be about 84 to 100 Mdaltons. HSV-2 genomes range in length of 154, 746 bp with base composition of 70.4% G C content and contain 78 genes. Nina Thayer, 2001:. HSV-2 Genome and Proteome Properties. The genes are characterized as either essential or dispensable for growth in cell culture. Essential genes regulate transcription and are needed to construct the virion. Http:/ stdgen.northwest...
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Urinary & Reproductive Infectious Disease: Special Thanks to...
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Monday, April 14, 2008. Teh Yong Jiann 1061105152. Tai Chu Cheng 1061107241. Tan Phit Ling 1071114866. Wong Li Chin 107111369. Researchers of Human Herpesviruses. Viewers and people who leave comments at this web site. Subscribe to: Post Comments (Atom). Identification of Gene, Function and Pathogen. Proposed New Diagnostic Strategy. Proposed New Prevention or Treatment. Proposed Vaccination and Eradication. HMM1019 Trimester 3, 2007/2008. View my complete profile. List of Members (Group 4).
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Urinary & Reproductive Infectious Disease: Proposed New Diagnostic Strategy
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Monday, April 14, 2008. Proposed New Diagnostic Strategy. By taking B cells (the body's antibody factories) and cracks them open to see if they are starting to produce antibodies. The body produces antibody responses and it is this first wave that seems to be killing the virus in the "immune" patients. This can distinguishe between new first wave acute antibodies and circulating antibodies remaining from a previous infection. Screening of latent virus in sacral ganglia at the base of the spine.
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Urinary & Reproductive Infectious Disease: Proposed New Prevention or Treatment
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Monday, April 14, 2008. Proposed New Prevention or Treatment. Vaccines against herpes have been developed but are still considered experimental drugs. Thus, more powerful vaccine should be developed to make our body more resistant to the HSV-2. We should always maintain a good personal hygiene to reduce the risk. Washing solution that applies to the genital area, which tends to kill the herpes virus, can be developed too. Http:/ www.idph.state.il.us/public/hb/hbherpes.htm. Http:/ www.nlm.nih....Prepared ...
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Urinary & Reproductive Infectious Disease: Reservoir & Transmission
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Monday, April 14, 2008. Urinary Tract Infections and Sexually Transmitted Infections. Herpes simplex virus type 2 only naturally occur in human. HSV-2 remains dormant in the sacral ganglia. At the base of the spine after it has entered the body. From there, it recurs in the genital area. Herpes simplex virus type 2 can be passed in the urine or genital discharge of an infected person. It may also transmitted through the rubbing of genital skin during sexual activity (shedding virus from the skin). The ri...
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Urinary & Reproductive Infectious Disease: Virulence Factors
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Monday, April 14, 2008. Figure: Symptoms of infected patient. 1 Wikipedia, 2008: Genital Infection. Internet:. Http:/ en.wikipedia.org/wiki/Herpes simplex#Genital infection. 2 Wikipedia, 2008: Herpes simple virus. Internet:. Http:/ en.wikipedia.org/wiki/Herpes simplex virus. 3 Dr Wagner, October 2003: Herpes Simplex Virus Research. Internet:. Http:/ darwin.bio.uci.edu/ faculty/wagner/hsv4f.html. 4 eMedicineHealth, 26 January, 2007: Genital Herpes. Internet:. 6 Virusys: HSV information. Internet:.
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Urinary & Reproductive Infectious Disease: Prevention & Treatment
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Monday, April 14, 2008. The most effective way to avoid transmission of genital herpes is to avoid from sexual contact. Or to be in a permanent mutually monogamous relationship with an uninfected partner. The use of latex condom. Furthermore, since the HSV-2 can also be spread by touching another part of the body after touching the sores, one must wash hands. With soap and water as soon as possible after touching the sores. Also, do not share towels or clothing with anyone. Figure: Male Latex Condom.
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Urinary & Reproductive Infectious Disease: Pathogenesis
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Monday, April 14, 2008. Figure: Pathogenesis of HSV. Dr Edward K. Wagner, October 2003:. 183; Generally, entry of viral into the host cell involves interactions of. Glycoproteins on the surface of the virus &. Receptors on the surface of the host cell. 183; For cellular entry of herpes virus, a glycoprotein embedded in the viral envelope, glycoprotein C binds to the heparan sulfate on the surface of the host cell, provides an initial contacts between viral and host cell. 183; The viral capsid ejects its ...