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MyriaScreen - diversity screening collection of 10,000 molecules from Sigma-Aldrich and TimTec

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TimTec

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TimTec

Tim Niyaz

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Ne●●rk , Delaware, 19714

United States

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ti●@timtec.net

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ti●@timtec.net

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MyriaScreen - diversity screening collection of 10,000 molecules from Sigma-Aldrich and TimTec
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3 screening collection
4 individual compounds
5 high throughput screen
6 compound collection
7 compound library
8 lead discovery
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Home | myriascreen.com Reviews

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MyriaScreen - diversity screening collection of 10,000 molecules from Sigma-Aldrich and TimTec

INTERNAL PAGES

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1

Publications

http://www.myriascreen.com/index.php/about/publications

Tuesday, August 30, 2016. Ianire Martin, Jarl Underhaug, et.al. Screening and Evaluation of Small Organic Molecules as ClpB Inhibitors and Potential Antimicrobials. J. Med. Chem., 2013, 56 (18), pp 7177 7189. DOI: 10.1021/jm400499k. Ana Jorge-Finnigan, Sandra Brasil, et.al. Pharmacological chaperones as a potential therapeutic option in methylmalonic aciduria cblB type. Hum Mol Genet. 2013 Sep 15;22(18):3680-9. doi: 10.1093/hmg/ddt217. Jamin, Augusta V. (2011). Chemical and Molecular Genetics App...

2

Press Release

http://www.myriascreen.com/index.php/press-release

Tuesday, August 30, 2016. MyriaScreen I 2005 Press Release. Click here to download MS II Diversity Library Data Sheet. Http:/ www.pr.com/press-release/3156. Http:/ www.bioscreening.net. New Product Feature in J Biomol Screening in 2006.

3

Statistics

http://www.myriascreen.com/index.php/analytics/statistics

Tuesday, August 30, 2016. Click here to download MS II Diversity Library Data Sheet.

4

About

http://www.myriascreen.com/index.php/about

Tuesday, August 30, 2016. TimTec LLC ( www.timtec.net. Click here to download MS II Diversity Library Data Sheet.

5

Diversity

http://www.myriascreen.com/index.php/analytics/diversity

Tuesday, August 30, 2016. MyriaScreen II structural Diversity score is 0.86899 to be exact or 0.87 to round it. What does the score stand for? Zooming from the entire structural fingerprints diversity in to structural scaffolds plane, there are about 4700 large common fragments in the collection out of which 1020 fragments are shared by 2-3 molecules. There are about 100 the most common fragments that show up in more than three structures. MyriaSreen II largest common fragments.

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LINKS TO THIS WEBSITE

imdlab.org imdlab.org

Curation » Integrated Molecular Discovery Laboratory -

http://www.imdlab.org/curation.php

IMDL Computational Chemical Biology Data Repository (maintained by Dr. Shuxing Zhang and Dr. Srinivas R Alla at MDACC). More data and software available inside MD Anderson and will be public soon. The datasets listed below are curated by us for our own research purposes obtained by the literature search; as well as from the existing freely available online resources like Drug bank and http:/ cheminformatics.org/. The zipped sdf file contains structure-activity data of 639 compounds targeted to hERG.

actimol.com actimol.com

NDL - Natural Derivatives Library

http://www.actimol.com/natural-products/ndl-natural-derivatives-library.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. NDL-3000 Natural Derivatives Library. In design and structural diversity.

actimol.com actimol.com

Flavonoid Derivatives

http://www.actimol.com/natural-products/flavonoid-derivatives.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. TimTec small collection of 500 Flavonoids Derivatives. Bullock A.N&#...

actimol.com actimol.com

ActiTarg-S (Serpins Inhibitors)

http://www.actimol.com/targeted-compound-libraries/actitarg-s-serpins-inhibitors.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. Serine Proteinase Inhibitors - ActiTarg-S Library.

actimol.com actimol.com

Plant Extracts

http://www.actimol.com/natural-products/plant-extracts.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. Traditional Use and Activity. Present advances in screening and separati...

actimol.com actimol.com

ActiProbe-10K

http://www.actimol.com/diversity-compound-libraries/actiprobe-series/actiprobe-10k.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. How to Select Compound Collections for Screening.

actimol.com actimol.com

Diversity

http://www.actimol.com/diversity-compound-libraries.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. TimTec's Diversity Analysis Software allows the assembly of libraries wh...

actimol.com actimol.com

Targeted

http://www.actimol.com/targeted-compound-libraries.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. These groups of compounds possess structural features and molecular latt...

actimol.com actimol.com

ApexScreen

http://www.actimol.com/diversity-compound-libraries/apexscreen.html

NPL - Natural Product Library. NDL - Natural Derivatives Library. ActiTarg-I (Potassium Channel Modulators). ActiTarg-N (Nuclear Receptor Ligands). ActiTarg-CNS (Central Nervous System Receptors Modulators). O-GlcNAc Transferase Inhibitors and Analogs. Aryl Hydrocarbon Receptor Ligands and Analogs. Inhibitors of Anthrax LF and Analogs. Potent TNF-alfa Inducers and Analogs. AG-205, Pgrmc1 Inhibitor. Building Blocks and Intermediates. How to Select Compound Collections for Screening. Formula: C19H21FN4O6MW...

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Tuesday, April 10, 2018. MyriaScreen Diversity Collection of drug-like screening compounds is now over 50% updated with new and more diverse structural material. New MyriaScreen II carries out the same design approach and combines premium molecular candidates hand-picked from Sigma-Aldrich and TimTec compound stocks. The selection of 10,000 high-purity and diverse molecules is the result of careful evaluation, multi-stage filtering, and refinement of two companies’ compound pools. The selection was refin...

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