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NephroGenex Investor Center - Innovative Therapies for Kidney Disease |

NephroGenex pharmaceutical company focuses on the development of therapeutics to treat kidney disease, an area of significant unmet medical need. Learn more about our work in exploring the unique promise against the fundamental causes of unmet medical needs.

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NephroGenex Investor Center - Innovative Therapies for Kidney Disease | | nephrogenex.investorhq.businesswire.com Reviews

https://nephrogenex.investorhq.businesswire.com

NephroGenex pharmaceutical company focuses on the development of therapeutics to treat kidney disease, an area of significant unmet medical need. Learn more about our work in exploring the unique promise against the fundamental causes of unmet medical needs.

INTERNAL PAGES

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1

Analyst Coverage | NephroGenex Investor Center - Innovative Therapies for Kidney Disease

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Annual Reports and Proxies. NephroGenex is covered by the following analysts. HC Wainwright and Co. Publications & Abstracts. PIONEER Phase 3 Program. Events & Presentations. Annual Reports & Proxies.

2

SEC Filings | NephroGenex Investor Center - Innovative Therapies for Kidney Disease

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Events & Presentations. Annual Reports & Proxies. PYRIDORIN (pyridoxamine dihydrochloride) is a registered trademark of NephroGenex, Inc.

3

all Press Releases | NephroGenex Investor Center - Innovative Therapies for Kidney Disease

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Annual Reports and Proxies. NephroGenex, Inc. Commences Voluntary Chapter 11 Proceeding; Seeks To Initiate Sale Process Under Section 363. 5/2/16 8:00 am EDT. RALEIGH, N.C.- ( BUSINESS WIRE. NephroGenex Provides Corporate Update. 2/24/16 9:20 am EST. NephroGenex to Presen...

4

Historical Stock Lookup | NephroGenex Investor Center - Innovative Therapies for Kidney Disease

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Events & Presentations. Annual Reports & Proxies. PYRIDORIN (pyridoxamine dihydrochloride) is a registered trademark of NephroGenex, Inc.

5

Corporate Governance | NephroGenex Investor Center - Innovative Therapies for Kidney Disease

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Annual Reports and Proxies. Nominating and Governance Committee Charter. Corporate Code of Conduct and Ethics and Whistleblower Policy. Publications & Abstracts. PIONEER Phase 3 Program. Events & Presentations. Annual Reports & Proxies.

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Board of Directors - NephroGenex, Inc.

http://www.nephrogenex.com/about-us/board-directors

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Richard J. Markham. Richard J. Markham has been Chairman of the Board of Directors since October, and a member since 2007. Mr. Markham is also a partner at the venture capital firm Care Capital, LLC. Prior to joining Care Capital in 2004, he was the Vice Chairman of the Management Board and COO of Aventis. Mr Markham received ...

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What is Chronic Kidney Disease?

http://www.nephrogenex.com/kidney-disease

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Chronic Kidney Disease Affects Over One-Third of Diabetics in the U.S. Patients with long-standing diabetes are at high risk for developing renal failure. Hypertension, uncontrolled blood sugar may pose irreversible kidney damage. Some common, and even early, indications of CKD are:. Muscle cramping at night. Dry, itchy skin.

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Diabetic Nephropathy: A Chronic Complication of Diabetes

http://www.nephrogenex.com/kidney-disease/diabetic-nephropathy

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Diabetic Nephropathy: A Chronic, Life-Threatening Complication of Diabetes. Within the bloodstream, the excessively high glucose reacts with proteins to form unstable compounds known as Schiff bases which are rapidly converted to more stable compounds known as Amadori products. These Amadori products are in-turn converted ...

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Earlier clinical studies with Pyridorin

http://www.nephrogenex.com/clinical-trials/previous-pyridorin-clinical-studies

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. PIONEER Phase 3 Program. Early Studies Show Clinical Benefit for Target Patient Population. Pyridorin well tolerated, with adverse event rates similar to placebo. Following several preclinical and Phase 1 studies, four placebo-controlled PYRIDORIN. PYR-206 was a Phase 2, multi-center, placebo-controlled, randomized, double-bli...

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What is Acute Kidney Injury?

http://www.nephrogenex.com/kidney-disease/acute-kidney-injury

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Many Critical Care Patients Are at Risk for Acute Kidney Injury. The condition can result in loss of kidney function in just 1-2 days. AKI is a serious condition that is estimated to affect between 7 and 18 percent of hospital inpatients. Major causes of acute kidney injury include:. The prognosis for AKI depends on the severi...

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Pyridorin: Treatment in development for diabetic nephropathy

http://www.nephrogenex.com/product-candidates/pyridorin

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. Pyridorin: A Novel Acting Compound to Improve Treatment of Diabetic Nephropathy. Addressing an unmet medical need to slow disease progression. Currently available treatments for diabetic nephropathy are effective but a significant residual risk remains. Unlike any currently approved therapies, Pyridor...

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Pipeline - NephroGenex, Inc.

http://www.nephrogenex.com/clinical-trials/pipeline

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. PIONEER Phase 3 Program. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Events & Presentations. Annual Reports & Proxies. PYRIDORIN (pyridoxamine dihydrochloride) is a registered trademark of NephroGenex, Inc.

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Publications & Abstracts - NephroGenex, Inc.

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. Publications & Abstracts. Clinical and Preclinical Activities of PYRIDORIN. Zheng F, Zeng YJ, Plati AR, Elliot SJ, Berho M, Potier M, Striker LJ, Striker GE. Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice. Kidney Int. 70:507-...Kakuta T,...

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Management Team - NephroGenex, Inc.

http://www.nephrogenex.com/about-us/management-team

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. John P. Hamill. Chief Executive Officer and Chief Financial Officer. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Events & Presentations. Annual Reports & Proxies. PYRIDORIN (pyridoxamine dihydrochloride) is a registered trademark of NephroGenex, Inc.

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NephroGenex - Innovation in the treatment of Kidney Disease

http://www.nephrogenexinc.com/about-us

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. NephroGenex is an innovator in the development of drugs to treat kidney disease, with a first indication in diabetic nephropathy. We have been pioneering the development of PYRIDORIN. We believe Pyridorin represents real hope for the millions of type 2 diabetic patients around the world who have diabetic nephropathy.

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Register Diabetische Nephropathie - Med. Klinik m.S. Nephrologie und Internistische Intensivmedizin, Charité-Universitätsmedizin Berlin

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NephroGenex Investor Center - Innovative Therapies for Kidney Disease |

Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Annual Reports and Proxies. Annual Reports and Proxies. 8/12/15 4:12 pm EDT. NephroGenex Reports Second Quarter 2015 Financial Results. 8/6/15 4:05 pm EDT. NephroGenex To Host Conference Call and Webcast on Second Quarter 2015 Financial Results on Thursday, August 13, 2015. Q1 2015 Quarterly Results.

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Innovative Therapies for Kidney Disease. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Publications & Abstracts. PIONEER Phase 3 Program. Investors & Media. Treating an underlying cause of diabetic kidney disease. Aiming to slow progression of the disease in 6 million patients at risk of kidney failure. Now enrolling pivotal Phase 3 PIONEER study in diabetic nephropathy. In Diabetic Nephropathy" alt="PYRIDORIN. In Diabetic Nephropathy" /. In Diabetic Nephropathy" PYRIDORIN. RALEIG...

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