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NEUROFIT - Preclinical Contract Research Organization (CRO) for CNS and PNS disorders

NEUROFIT is a preclinical Contract Research Organization specialising in the evaluation of treatments for central and peripheral nervous system disorders. We offer a comprehensive list of in vitro and in vivo models covering a wide range of indications. NEUROFIT aims to facilitate your preclinical drug development by proposing the best models for your needs. Our goal is to accelerate the development of your programs by providing cost-effective methods for compound evaluation.

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NEUROFIT - Preclinical Contract Research Organization (CRO) for CNS and PNS disorders | neurofit.com Reviews

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NEUROFIT is a preclinical Contract Research Organization specialising in the evaluation of treatments for central and peripheral nervous system disorders. We offer a comprehensive list of in vitro and in vivo models covering a wide range of indications. NEUROFIT aims to facilitate your preclinical drug development by proposing the best models for your needs. Our goal is to accelerate the development of your programs by providing cost-effective methods for compound evaluation.

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neurofit@neurofit com,accreditations,therapeutic area,adhd,animal model,scopolamine,t maze,allergic contact dermatitis,animal models,ovalbumine,oxazolone,alzheimer's disease,passive avoidance,novel object recognition,aged mouse,methyllycaconitine,anxiety

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NEUROFIT - Preclinical Contract Research Organization (CRO) for CNS and PNS disorders | neurofit.com Reviews

https://neurofit.com

NEUROFIT is a preclinical Contract Research Organization specialising in the evaluation of treatments for central and peripheral nervous system disorders. We offer a comprehensive list of in vitro and in vivo models covering a wide range of indications. NEUROFIT aims to facilitate your preclinical drug development by proposing the best models for your needs. Our goal is to accelerate the development of your programs by providing cost-effective methods for compound evaluation.

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neurofit.com

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ELEVATED PLUS MAZE in rodents

http://www.neurofit.com/tech-epm.html

ELEVATED PLUS MAZE in rodents. Compound testing addresses the effect of acute treatment on the total duration of time spent in the open arms. Investigation of the effect of subchronic treatment is also possible. Induces a significant increase in the time spent in the open arms. Boulevard S. Brant. BIOPARC - 67 400.

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HOME - NEUROFIT - Pre-clinical contract research for CNS, PNS and Oncology

http://www.neurofit.com/index.html

Is a Contract Research Organisation. CRO) specialising in the evaluation of treatments for peripheral and central nervous system disorders. Offers a long list of in vivo. Validated methods and disease models for drug screening. Boulevard S. Brant. 33(0)3 88 65 16 06. 33(0)3 88 65 16 22. Anxiety, depression, schizophrenia, cognition . Models for several diseases:. Parkinson's Disease, epilepsy . Rat primary neuronal culture models and assays:. Neurotoxicity, neuroprotection . Examples of Screening Tests.

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Boulevard S. Brant. 33(0)3 88 65 16 06. 33(0)3 88 65 16 22. If you need more information, please do not hesitate to contact us.

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PARKINSON'S DISEASE

http://www.neurofit.com/tech-parkinson.html

EFFECT OF COMPOUNDS ON DAMAGE INDUCED BY MPP. Parkinson disease (PD) involves a selective degeneration of nigrostriatal dopaminergic (DA) neurons. This pathology can be modeled in experimental animals by the administration of MPTP (. 1-metyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. A toxin which selectively destroys DA neurons and causes anatomical, behavioral, and biochemical changes similar to those seen in Parkinson's disease. In vivo MPTP is converted to MPP. In upper panel it is phase contrast photog...

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DIABETIC NEUROPATHY in the rat

http://www.neurofit.com/tech-diabet.html

DIABETIC NEUROPATHY in the rat. In the rat :. ANIMAL MODEL FOR PERIPHERAL NERVE DEGENERATION. Compound testing addresses the effect of chronic curative treatment of diabetic rats on:. Recovery of nerve function. Prevention of loss of IENF. Hyperglycemia induced by STZ in Sprague Dawley rats. Reduction of sensory nerve conduction velocity (SNCV). In STZ-rats. Recording is performed at the level of the tail. Graph showing the progressive loss of IENF. In skin biopsy from diabetic rats. BIOPARC - 67 400.

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For CNS and PNS disorders. 33(0)3 88 65 16 06. Validated in vitro and in vivo disease and safety models for drug screening. Amyloid beta ( Aβ ). Amyloid β intoxication (Aβ1-40/1-42). Viability and survival tests. Basal Amyloid β production. Measure of neuromuscular junction and nerve fiber morphometry. Nerve / Muscle coculture. Innervated muscle fiber area. Cortical neurons : neurite outgrowth. IPSC : neurite outgrowth. Pentylenetetrazol ( PTZ ). INFLAMMATION ( acute ). Carrageenan mouse air pouch. NEURO...

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