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NeuroImmunology | Updating on disimmune neurological disorders

Updating on disimmune neurological disorders

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Fingolimod, two years view | NeuroImmunology

https://neuroimmunology.wordpress.com/2011/06/02/fingolimod-two-years-view

Updating on disimmune neurological disorders. Fingolimod, two years view. The last issue of the Lancet Neurology. Journal, has published the extension phase study of the TRANSFORMS trial. Briefly, the TRANSFORMS trial was a randomized controlled trial comparing i.m. interferon beta 1a versus two different doses of fingolimod (0.5mg and 1.25mg). Its results were published on New England Journal of Medicine. 2 June, 2011. Laquo; The shameful story of Rituximab in Multiple Sclerosis. Do you want to comment?

2

KIR4.1 antibodies: A revolution in multiple sclerosis | NeuroImmunology

https://neuroimmunology.wordpress.com/2012/07/16/kir4-1-antibodies-a-revolution-in-multiple-sclerosis

Updating on disimmune neurological disorders. KIR41 antibodies: A revolution in multiple sclerosis. This week we had the opportunity to read a paper in the New England Journal of Medicine, describing, in my opinion, a breakthrough finding in MS. It’s published by Srivastava and coworkers, from the University of Munich. It describes the presence of antibodies against the KIR4.1 potassium channel in almost 50% of MS patients. Being, in my opinion, much less important from the patient care point of view.

3

Pills for multiple sclerosis | NeuroImmunology

https://neuroimmunology.wordpress.com/2012/06/24/pills-for-multiple-sclerosis

Updating on disimmune neurological disorders. Pills for multiple sclerosis. At this moment there is only one treatment fully available in Europe, fingolimod. Gilenya), four more laquinimod. Have completed phase III trials and another one, firategrast. Is still on phase II trials but shows promising results. So, let’s start:. Fingolimod is currently available in the US and Europe. We’ve wrote about it before. Annualized relapse rate showed a 50% reduction in comparison to placebo. Of the drug. Other s...

4

The shameful story of Rituximab in Multiple Sclerosis | NeuroImmunology

https://neuroimmunology.wordpress.com/2011/03/27/the-shameful-story-of-rituximab-in-multiple-sclerosis

Updating on disimmune neurological disorders. The shameful story of Rituximab in Multiple Sclerosis. Two weeks ago a few collegues from Spain and I attended the 3rd Preceptorship Program in MS at Steven Hauser’s department in UCSF. The scientific program and the overall quality of the course were outstanding. We had the opportunity to hear and ask those that have been ahead of MS research in the last years ( Oksenberg. And, of course, Hauser. The one about Rituximab. And started the whole process again&#...

5

Fingolimod unexpected death | NeuroImmunology

https://neuroimmunology.wordpress.com/2011/12/25/fingolimod-unexpected-death

Updating on disimmune neurological disorders. A few days ago we had access to this alert in Medscape. An MS patient, that had completed the 6-hour vigilance period after the first dose of fingolimod, died unexpectedly the next day. We don’t know much about it and we should wait until this case is resolved and an official report released. We only know that the patient was already taking beta-blockers and calcium channel antagonists. 25 December, 2011. Laquo; Rituximab vs Ocrelizumab in multiple sclerosis.

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NeuroImmunology | Updating on disimmune neurological disorders

Updating on disimmune neurological disorders. Moving to NeuroImmunology Club. It’s been a while since i worte the last post here. Many subjects should have been discussed and others updated but several things, one of them being the Twitter time sink, prevented more frequent updates on the blog. Two additional features have been added to the blog:. This site will still be available but won’t be updated anymore so, if you want to keep updated in NeuroImmunology, please change your feed to http:/ neur...

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How to help us? Diagnosis, treatment and research on inflammatory diseases of the brain. Better Diagnosis can lead to a better personal treatment. You can benefit from an early diagnosis. Artículo de revisión en @NEJM. Mediadas por anticuerpos by #josepdalmau. Antibody-Mediated Encephalitis NEJM https:/ t.co/vMIkEnoQWa. Follow us on Twitter. XXII Award 2018 Claustre de Doctors de la Universitat de Barcelona. The Cloister of Doctors of the Universitat de Barcelona. Wednesday, 8 March 2017. This week one o...

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Neuroimmunopharmacology

Unification of 3 research domains. Acknowledges and embraces the bi-directional relationship between the immune system and the brain. Immune to brain communication. Brain to immune communication. Examine the interplay between neuronal and non-neuronal cells of the central nervous system. Peripheral immune cells in the brain.