NeuroLINCS is an NIH-funded collaborative effort between research groups with expertise in iPSC technology, disease modeling, OMICS methods, and computational biology. We seek to understand the causes of neurological diseases and to develop new therapies.
http://www.neurolincs.org/
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Welcome to NeuroLINCS - NeuroLINCS | neurolincs.org Reviews
https://neurolincs.org
NeuroLINCS is an NIH-funded collaborative effort between research groups with expertise in iPSC technology, disease modeling, OMICS methods, and computational biology. We seek to understand the causes of neurological diseases and to develop new therapies.
neurolincs.org
Tools - NeuroLINCS
http://neurolincs.org/tools
AChroMap is a data integration tool for transcriptomic and epigenomic data. It generates a list of enriched motifs in open chromatin regions (as assayed by ATAC-seq or DNase-seq) for a given set of differentially expressed genes. Read More at PLOS Computational Biology. Read more at Nature Methods. We’ve released a custom ‘flavor’ of Galaxy, a docker image producing a galaxy optimized for our analyzes, available to the community. Learn more about Galaxy. The NeuroLINCS Galaxy Instance.
NeuroLINCS
http://neurolincs.org/publications
ALS Disrupts Spinal Motor Neuron Maturation and Aging Pathways Within Gene Co-Expression Networks. Ho R, Sances S, Gowing G, Amoroso MW, O’Rourke JG, Sahabian A, Wichterle H, Baloh RH, Sareen D, Svendsen CN. Nat Neurosci. 2016 Sep;19(9):1256-67. doi: 10.1038/nn.4345. Revealing disease-associated pathways by network integration of untargeted metabolomics. Pirhaji L, Milani P, Leidl M, Curran T, Avila-Pacheco J, Clish CB, White FM, Saghatelian A, Fraenkel E. Haeusler AR, Donnelly CJ, Rothstein JD. Nucleocy...
NeuroLINCS
http://neurolincs.org/about
NeuroLINCS
http://neurolincs.org/data
The NeuroLINCS Center creates a wealth of cellular data that is patient-specific in the context of their baseline genetic perturbations and in the presence of other environmental stressors. Motor neurons (iMNs) are produced from induced pluripotent stem cell (iPSC) technologies and these cells are analyzed using epigenomics, transcriptomics, proteomics, and robotic imaging. IPSC - ALS, SMA and Control (unaffected) subject-derived iPSC lines. IMN long differentiation protocol. Data release Spring of 2017.
People - NeuroLINCS
http://neurolincs.org/people
Finkbeiner, Steve (MD, PhD). Dr Finkbeiner studies the molecular mechanisms that are responsible for learning, memory and neurodegeneration. A better understanding of the mechanisms that control memory formation in neurons will yield crucial insights into the development and progression of neurodegenerative diseases - and the memory disorders that often characterize them. Fraenkel, Ernest (PhD). Rothstein, Jeffrey (MD, PhD). Professor Rothstein is a neurologist/neurobiologist with a major commitment to i...
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NIH LINCS Program
http://www.lincsproject.org/news
Library of Integrated Network-Based Cellular Signatures. Data and Signature Generation Centers. BD2K-LINCS Data Coordination and Integration Center. Pilot Phase 1 Centers. Data Production and Analysis (U54). Tools & Databases. June 16th, 2016. Sherry Jenkins No Comments. By the Crowd Innovation Lab at Harvard, the Broad Institute, and NIH LINCS Program. The LINCS Center for Transcriptomics. Registration is open at. Http:/ crowdsourcing.topcoder.com/cmap. June 2nd, 2016. Sherry Jenkins No Comments. Side e...
Tools & Databases - NIH LINCS Program
http://www.lincsproject.org/data/tools-and-databases
Library of Integrated Network-Based Cellular Signatures. Data and Signature Generation Centers. BD2K-LINCS Data Coordination and Integration Center. Pilot Phase 1 Centers. Data Production and Analysis (U54). Tools & Databases. Tools & Databases. BD2K-LINCS Data Coordination and Integration Center. Enrichr is an easy to use intuitive enrichment analysis web-based tool providing various types of visualization summaries of collective functions of gene lists. PMID: 23586463. SEP-L1000 (side effect prediction...
ALS Research Forum | ALS/MND 2016: Analyzing the Exposome: A New Approach to Finding Environmental Causes of ALS
http://www.alsresearchforum.org/analyzing-the-exposome-a-new-approach-to-finding-environmental-causes-of-als
Discovering a Common Goal,. Discovering a Common Goal,. Enter search term, click "enter". Filter articles published since 2015 by topic, disease, or article type. Results are filtered to show all matching articles from a particular category, and to show only articles that match all selected categories. Spinal cord or traumatic brain injury. ALS Mouse Model Database. Drugs in Development Database. Preclinical Study Design Resources. Enter search term, click "enter". For instance, if "Biomarkers" and "Gene...
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Neuro Limbic Conditioning – Just another WordPress site
NLC QUANTUM TRAINER Level 1. NLC QUANTUM TRAINER Level 2. NEURO - LIMBIC CONDITIONING. Unleash The Coach Within. Chat to our team to see if Neuro Limbic Conditioning is right for you. What is Neuro-Limbic Conditioning? The 3 Levels of Coaching. Neuro Limbic Conditioning - Level 1. Neuro Limbic Conditioning - Level 2. Neuro Limbic Conditioning - Level 3. Quantum Trainer Level 3 is about helping you to become the best coach you can be. We delve into the science of energy medicine, universal laws, how t...
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Welcome to NeuroLINCS - NeuroLINCS
NeuroLINCS is an NIH-funded collaborative effort between research groups with expertise in iPSC technology, disease modeling, OMICS methods, and computational biology. We seek to understand the causes of neurological diseases and to develop new therapies. Induced Pluripotent Stem Cell (iPSC). IPSCs are generated using the latest techniques to reprogram, expand and characterize human iPS cells from human skin or blood tissues of healthy subjects and diseased patients. Learn More. ATAC-Seq is a transposase...
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