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Skip to primary content. Skip to secondary content. July 18, 2012. Is an lipophilic (fat-soluble) analogue of Vitamin B1 (thiamine) which crosses the blood-brain-barrier easier than thiamine itself. Its main mechanism of action is thought to occur in the part of the brain which affects motivation and arousal, explaining its positive effects on mood and energy. Sulbutiamine, also known as Arcalion, This substance crosses the blood-brain barrier and increases levels of thiamine and other brain chemicals re...
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