norgen.ki.se

NORGEN

NORGEN is a Nordic network of national centres of excellence which is funded by the Nordic research board, NordForsk. NORGEN aims at building a transdisciplinarity network within the field of nuclear (orphan) hormone receptor research with the involvement of both basic and clinical scientists from a range of disciplines, including human genetics, cell biology, molecular biology, human and comparative physiology and endocrinology as well as bioinformatics and the use of state-of-the-art technology pla...

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NORGEN | norgen.ki.se Reviews

<META> DESCRIPTION

NORGEN is a Nordic network of national centres of excellence which is funded by the Nordic research board, NordForsk. NORGEN aims at building a transdisciplinarity network within the field of nuclear (orphan) hormone receptor research with the involvement of both basic and clinical scientists from a range of disciplines, including human genetics, cell biology, molecular biology, human and comparative physiology and endocrinology as well as bioinformatics and the use of state-of-the-art technology pla...

<META> KEYWORDS

1 network structure

2 junior committee

3 network activity

4 discussion forum

5 network publications

6 about the network

7 news

8 network partners

9 jan åke gustafsson

10 hilde nebb

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network structure,junior committee,network activity,discussion forum,network publications,about the network,news,network partners,jan åke gustafsson,hilde nebb,karsten kristiansen,eckardt treuter,karin dahlman wright,external links,nordforsk,nursa

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NORGEN | norgen.ki.se Reviews

https://norgen.ki.se

NORGEN is a Nordic network of national centres of excellence which is funded by the Nordic research board, NordForsk. NORGEN aims at building a transdisciplinarity network within the field of nuclear (orphan) hormone receptor research with the involvement of both basic and clinical scientists from a range of disciplines, including human genetics, cell biology, molecular biology, human and comparative physiology and endocrinology as well as bioinformatics and the use of state-of-the-art technology pla...

INTERNAL PAGES

norgen.ki.se

1

NORGEN

http://www.norgen.ki.se/publications.html

The following papers have been published as a collaboration between the network partners during the operation period of the network funding. Madsen L, Petersen RK, Steffensen KR, Pedersen LM, Hallenborg P, Ma T, Frøyland L, Døskeland SO, Gustafsson JA, Kristiansen K. Activation of liver X receptors prevents statin-induced death of 3T3-L1 preadipocytes. J Biol Chem. 2008 Aug 15;283(33):22723-36. The E3 ubiquitin ligase RNF31 cooperates with DAX-1 in transcriptional repression of steroidogenesis.

2

NORGEN

http://www.norgen.ki.se/structure.html

Karolinska Institutet, Sweden. Knut R. Steffensen. Karolinska Institutet, Sweden. Olli A. Jänne. University of Helsinki, Finland. University of Oslo,. University of Copenhagen, Denmark. Karolinska Institutet, Sweden. Karolinska Institutet, Sweden. Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses. Knut R. Steffensen. Olli A. Jänne. University of Southern Denmark, Odense. Last modified by: David Brodin March 2010.

3

NORGEN

http://www.norgen.ki.se/janne_o.html

Olli A. Jänne. MD PhD. Professor. University of Helsinki, Biomedicum Helsinki. PO Box 63, Haartmaninkatu. E-mail: olli.janne@helsinki.fi. Our research is centered around genome-wide landscape of AR function. In this work, the group will delineate how AR-dependent gene networks are established in prostate and lung cancer cells and compare these networks to those regulated by glucocorticoid receptor. Knut R. Steffensen. Olli A. Jänne. University of Southern Denmark, Odense.

4

NORGEN

http://www.norgen.ki.se/dahlman-wright_k.html

Dept of Biosciences and Nutrition, NOVUM. SE-14157 Stockholm, Sweden. Phone: 46 8 524 81089 (office). Phone: 46 707266541 (mobile). E-mail: karin.dahlman-wright@ki.se. Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses. GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response. Knut R. Steffensen. Olli A. Jänne.

5

NORGEN

http://www.norgen.ki.se/steffensen_k.html

Knut R. Steffensen. Department of Biosciences and Nutrition. S-14157 Huddinge/Stockholm, Sweden. E-mail: knut.steffensen@ki.se. My research focus is centered on the oxysterol nuclear receptor LXR (Liver X Receptor). The two genes, LXRα and LXRß, are crucial sensors and regulators of cholesterol and lipid homeostasis in several metabolic tissues including liver, macrophages and intestine and they have recently emerged as key regulators of inflammation and cell cycle pathways. GPS2-dependent corepressor/SU...

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NORGEN is a Nordic network of national centres of excellence which is funded by the Nordic research board, NordForsk. NORGEN aims at building a transdisciplinarity network within the field of nuclear (orphan) hormone receptor research with the involvement of both basic and clinical scientists from a range of disciplines, including human genetics, cell biology, molecular biology, human and comparative physiology and endocrinology as well as bioinformatics and the use of state-of-the-art technology pla...

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