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Optimum: Translating laboratory discoveries into clinical treatments. Optimum focuses on linking academic discoveries with commercial applications in order to provide the maximum benefits to cancer research and patients. Opening its doors to its first two employees in late 2003, Optimum has grown to employ several Ph.D.-level scientists and an extremely strong and experienced support staff. Please excuse our mess.

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Home | optimumtx.com Reviews

https://optimumtx.com

Optimum: Translating laboratory discoveries into clinical treatments. Optimum focuses on linking academic discoveries with commercial applications in order to provide the maximum benefits to cancer research and patients. Opening its doors to its first two employees in late 2003, Optimum has grown to employ several Ph.D.-level scientists and an extremely strong and experienced support staff. Please excuse our mess.

INTERNAL PAGES

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1

News

http://www.optimumtx.com/news.html

November 12, 2009. Optimum presented a poster at the 2009 AAPS convention in LA on Thursday, November 12 entitled: Tumor penetrating microparticles for intraperitoneal treatment of pancreatic cancer. Discovery of Potential Pancreatic Cancer Treatment. November 4, 2009; reprinted from Drug Discovery and Development. Tiny particles that can carry drugs and target cancer cells may offer treatment hope for those suffering with pancreatic cancer. New research to be presented in November at the American As...

2

Drug Delivery

http://www.optimumtx.com/drug-delivery.html

Jang, S. H., Wientjes, M.G., Lu, D., and Au, J.L. Drug delivery and transport to solid tumors. Pharmaceutical Res., 20 (9):1337-50, 2003. Lu, D, Wientjes, M.G., Lu, Z., and Au, J.L-S. Tumor Priming Enhances Delivery and Efficacy of Nanomedicines, J. Pharmacol. Exp. Ther., 322(1):80-8, 2007.

3

Bladder

http://www.optimumtx.com/bladder.html

Lu, Ze, Yeh, T.K., Tsai, M., Au, J.L.-S., and Wientjes, M.G. Paclitaxel-loaded gelatin nanoparticles for intravesical bladder cancer therapy. Clin. Cancer Res., 10:7677-84, 2004. Xin, Y., Lyness, G., Chen, D., Song, S., Wientjes, M.G., and Au, J.L. Low dose suramin as a chemosensitizer of bladder cancer to mmc. J. Urol., 174:322-7, 2005.

4

Publications

http://www.optimumtx.com/publications.html

1 Jang, S. H., Wientjes, M.G., Lu, D., and Au, J.L. Drug delivery and transport to solid tumors. Pharmaceutical Res., 20 (9):1337-50, 2003. 2 Lu, Ze, Yeh, T.K., Tsai, M., Au, J.L.-S., and Wientjes, M.G. Paclitaxel-loaded gelatin nanoparticles for intravesical bladder cancer therapy. Clin. Cancer Res., 10:7677-84, 2004. 6 Wang, J., Lu, Z., and Au, J.L.-S. Protection against chemotherapy-induced alopecia. Pharmaceutical Res., 23 (11): 2505-2514, 2006. 8 Lu, D., Wientjes, M.G., Lu, Z., and A...9 Lu, Z.,...

5

About Us

http://www.optimumtx.com/about-us.html

Jessie Au, Pharm.D., Ph.D., Chief Scientific Officer and CEO. Dr Au received her Pharm.D. and Ph.D. degrees from University of California. San Francisco and postdoctoral training at Roswell Park Cancer Institute. Dr. Au. Is recognized for her accomplishments in pharmaceutical and cancer research. Her breadth of interests and training in both clinical and basic sciences have. Allowed her to excel in translating her laboratory discoveries in cellular and. Guill Wientjes, Ph.D., Principal Scientist.

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