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The Pagliarini Lab at the University of Wisconsin-Madison is an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation and basic metabolic function of mitochondria.

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CONTACTS AT PAGLIARINILAB.ORG

Dave Pagliarini

Dave Pagliarini

Bioc●●●●stry

Ma●●on , Wisconsin, 53706

US

1.60●●●●3254
pa●●●●●●●●@wisc.edu

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Dave Pagliarini

Dave Pagliarini

Bioc●●●●stry

Ma●●on , Wisconsin, 53706

US

1.60●●●●3254
pa●●●●●●●●@wisc.edu

View this contact

Dave Pagliarini

Dave Pagliarini

Bioc●●●●stry

Ma●●on , Wisconsin, 53706

US

1.60●●●●3254
pa●●●●●●●●@wisc.edu

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The Pagliarini Lab at the University of Wisconsin-Madison is an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation and basic metabolic function of mitochondria.
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Pagliarini Lab - Home | pagliarinilab.org Reviews

https://pagliarinilab.org

The Pagliarini Lab at the University of Wisconsin-Madison is an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation and basic metabolic function of mitochondria.

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1

Pagliarini Lab - Publications All

http://www.pagliarinilab.org/publications.php

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia C, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, Werner KM, Jochem A, Westphall MS, Rensvold JW, Taylor RW, Prokisch H, Kim JJ, Coon JJ, Pagliarini DJ. 2016 Aug 18;63(4):621-32. Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity. 2016 Aug 18;63(4):608-20. Multiplexed Qu...

2

Pagliarini Lab - Current Members

http://www.pagliarinilab.org/current_members.php

BS, University of Michigan (Biochemistry). PhD, Van Andel Institute Graduate School (CMB). BS, University of Notre Dame (Chemistry). PhD, University of Wisconsin-Madison (Biochemistry). BS, Peking University (Chemistry). Year Chemistry Graduate Student. BS, University of Pennsylvania. Year iRiB Graduate Student. BS, University of North Carolina-Chapel Hill (Chemistry). Year IPiB Graduate Student. NIH Biotechnology Trainee (BTP). BS, Creighton University (Chemistry). Year IPiB Graduate Student.

3

Pagliarini Lab - Instrumentation

http://www.pagliarinilab.org/instrumentation.php

We have established a robust instrumentation platform to catalyze our investigations of mitochondrial function. Our collection includes state-of-the-art instruments for proteomics, metabolomics, bioenergetics, protein purification, microscopy and plate-based assays. Along with our standard laboratory equipment, these instruments enable us to integrate focused biochemistry and cell biology with large-scale systems analyses. Live cell and mitochondrial bioenergetics. Respiration and glycolysis measurements.

4

Pagliarini Lab - News 2015

http://www.pagliarinilab.org/news_2015.php

IPiB) joins the lab as first year graduate student. CMB student Jarred Rensvold. Successfully defended his doctoral thesis entitled, Adaptive mitochondrial biogenesis response to iron deprivation. Jarred will remain with the lab as an Assistant Scientist. Is selected to direct the Morgridge Metabolism Theme. The lab moves into the Morgridge Institute for Research on campus. Undergraduate Isabel Johnson enrolls as PhD student in UCSF’s Tetrad Program. IPiB student Jonathan Stefely. IPiB student Mike Veling.

5

Pagliarini Lab - Overview

http://www.pagliarinilab.org/overview.php

Despite this central role for mitochondria in human health and disease, much of the basic biology of these organelles remains obscure. By blending classic biochemistry, molecular and cellular biology, and bioenergetics with large-scale proteomics and systems approaches, our lab aims to systematically annotate the functions of uncharacterized mitochondrial proteins (MXPs) and to establish the detailed mechanisms that drive essential mitochondrial pathways.

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Mitochondrial Protein Partnership - Links

http://www.mitoproteins.org/links.html

Mito Disease Action Committee. Protein Data Bank (PDB). United Mitochondria Disease Foundation (UMDF). The Mitochondrial Protein Partnership is supported by NIH/NIGMS grant number U01GM094622. Contact us with questions, comments, or accessibility Issues at cesginfo@biochem.wisc.edu. Protein Structure Initiative Quick Links PSI MR.

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Faculty |

http://nutrisci.wisc.edu/people/faculty-staff

Dr Dale A. Schoeller has been selected for the 2016 Friends of Albert (Mickey) Stunkard Award! Award-winning breastfeeding research from UW/MSU team. The 2016 Wisconsin wine grape season. Symmetry crucial for building key biomaterial collagen in the lab. CALS undergrads get in-the-field experience during summer ARS internships. The Simple Device That Transformed The Dairy Industry. International ag research Audio. Fruit flies help explain differences between males and females. Go to the top of the page.

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Genomic Sciences Training Program - U Wisconsin

http://gstp.wisc.edu/people/trainers.htm

Graduate, Undergrad. and. Link to Seminar Listings. Fostering new paradigms for the biological sciences. GSTP Faculty Name /. Studying the regulation of gene expression at the interface of chemistry biology and genomics, dissecting genome-wide transcriptional cascades. Genomic approaches to characterize multiple myeloma. Molecular genetics of diabetes and insulin resistance; cell biology of lipoprotein assembly and cholesterol trafficking. Cell and Regenerative Biology. Development and application of mac...

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Pagliarini Lab - Home

Welcome to the Pagliarini Lab in the Department of Biochemistry at UW-Madison. We are an interdisciplinary team of scientists driven to understand the biochemical underpinnings of mitochondrial dysfunction in human diseases. Together, we integrate large-scale methodologies with traditional biochemistry to investigate the modulation, adaptation and basic metabolic function of mitochondria. Dave is promoted to Associate Professor. Brendan defends his thesis. Brendan receives a Denton Award.

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