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Pathways in PD | Uncovering mechanisms that lead to neurodegeneration

The presynaptic protein alpha-synuclein (AS) plays a crucial role in Parkinson’s Disease (PD) pathogenesis, as missense point mutations or multiplications of SNCA, the gene encoding for AS, lead to autosomal dominant PD and the phenotype is dependent on a gene-dosage effect. Steady state levels of AS, determined by production, degradation and secretion of the protein,…

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Pathways in PD | Uncovering mechanisms that lead to neurodegeneration | pathwaysinpd.com Reviews
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The presynaptic protein alpha-synuclein (AS) plays a crucial role in Parkinson’s Disease (PD) pathogenesis, as missense point mutations or multiplications of SNCA, the gene encoding for AS, lead to autosomal dominant PD and the phenotype is dependent on a gene-dosage effect. Steady state levels of AS, determined by production, degradation and secretion of the protein,…
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Pathways in PD | Uncovering mechanisms that lead to neurodegeneration | pathwaysinpd.com Reviews

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The presynaptic protein alpha-synuclein (AS) plays a crucial role in Parkinson’s Disease (PD) pathogenesis, as missense point mutations or multiplications of SNCA, the gene encoding for AS, lead to autosomal dominant PD and the phenotype is dependent on a gene-dosage effect. Steady state levels of AS, determined by production, degradation and secretion of the protein,…

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Uncovering mechanisms that lead to neurodegeneration. The presynaptic protein alpha-synuclein (AS) plays a crucial role in Parkinson’s Disease (PD) pathogenesis, as missense point mutations or multiplications of SNCA, the gene encoding for AS, lead to autosomal dominant PD and the phenotype is dependent on a gene-dosage effect. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Email (Address never made public). This slideshow requires JavaScript.

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