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PK/PD

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development.

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PK/PD | pk-pd.blogspot.com Reviews

https://pk-pd.blogspot.com

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development.

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pk-pd.blogspot.com pk-pd.blogspot.com
1

PK/PD: April 2009

http://pk-pd.blogspot.com/2009_04_01_archive.html

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Thursday, April 30, 2009. Its been a while since I had posted anything here. While I have been busy juggling between being a dad to a month old boy and trying to finish thesis work, I try to find time to recap and update myself on PK/PD. Here is a link with lots of presentations on various concepts of clinical pharmacology by authors of the book " Principles of Clinical Pharmacology". Links to this post.

2

PK/PD: Phase 0 Microdosing/Microtracing in Phase 1 Studies

http://pk-pd.blogspot.com/2009/06/phase-0-microdosingmicrotracing-in.html

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Tuesday, June 9, 2009. Phase 0 Microdosing/Microtracing in Phase 1 Studies. Stephen Dueker, PhD, President/CEO of Vitalea Science. Recently commented on my previous post on Microdosing Studies. What needs to be understood is that AMS is much more than Phase 0. N, etc.can all be ascertained in a microdosing study. This indeed is what the specificity of a tracer and the sensitivity of AMS uncover. It is everyone&#821...

3

PK/PD: December 2013

http://pk-pd.blogspot.com/2013_12_01_archive.html

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Friday, December 27, 2013. Bioavailability/Bioequivalence Regulatory Guidance Documents- Link Updated. After a long time, I have gone back and updated the guidance documents in my original post " Bioavailability/Bioequivalence Guidelines. Links to this post. Wednesday, December 25, 2013. And are available for free under open access. Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development.

4

PK/PD: PKPD Regulatory Guidances

http://pk-pd.blogspot.com/2008/12/pop-pkpd-guidances.html

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Monday, December 15, 2008. After a short hiatus, I am back and hope to continue posting frequently. Ok. If you are planning to work in the industry or already dealing with population PK studies, then you may want to read the guidances pertaining to PK/PD. These guidances provide recommendations on study design, data analysis and report writing which can be very helpful in your work. Population Pharmacokinetics [ PDF.

5

PK/PD: Bioavailability/Bioequivalence Regulatory Guidance Documents- Link Updated

http://pk-pd.blogspot.com/2013/12/bioavailabilitybioequivalence.html

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Friday, December 27, 2013. Bioavailability/Bioequivalence Regulatory Guidance Documents- Link Updated. After a long time, I have gone back and updated the guidance documents in my original post " Bioavailability/Bioequivalence Guidelines. Subscribe to: Post Comments (Atom). View my complete profile. AAPS Modeling and Simulation Focus Group. Helmut Schütz (BE/BA Forum). Pharma’s Cutting Edge.

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pharmacometricsonline.blogspot.com pharmacometricsonline.blogspot.com

Pharmacometrics Online: Good quote

http://pharmacometricsonline.blogspot.com/2009/01/good-quote.html

Saturday, January 17, 2009. Great art is found wherever man achieves an understanding of self and is able to express himself fully in the simplest manner. Odysseas Elytis (1979 Nobel Laureate in Literature The magic of Papadiamantis. Found this quote in Preface for "Modeling in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics. . Subscribe to: Post Comments (Atom). Benefits of using modeling and simulation in drug development. Visitors to this page.

pharmacometricsonline.blogspot.com pharmacometricsonline.blogspot.com

Pharmacometrics Online: Compartmental analysis of drug distribution

http://pharmacometricsonline.blogspot.com/2008/12/compartmental-analysis-of-drug.html

Tuesday, December 30, 2008. Compartmental analysis of drug distribution. 1 Post absorptive transfer of drug from one location to the other. Compartmental modles (ordinary differential equations). Distributed models (partial differential equations) distribution from an organ/tissue. 2 Extracellular = interestitial vascular. 6Thyroxine tightly bound to proteins 99.7%. 7 C=A"e-at B"e-bt: Data equation. Dx/dt=-(K10 k21)X1 k12X2: Model equation. 9Significance of drug distribution rate. Visitors to this page.

pharmacometricsonline.blogspot.com pharmacometricsonline.blogspot.com

Pharmacometrics Online: January 2009

http://pharmacometricsonline.blogspot.com/2009_01_01_archive.html

Saturday, January 17, 2009. Great art is found wherever man achieves an understanding of self and is able to express himself fully in the simplest manner. Odysseas Elytis (1979 Nobel Laureate in Literature The magic of Papadiamantis. Found this quote in Preface for "Modeling in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics. . Thursday, January 1, 2009. I wish all of you a Happy an Prosperous New year 2009. Subscribe to: Posts (Atom). Benefits of using modeling and simulation in drug development.

tgordi.wordpress.com tgordi.wordpress.com

May 2016 – Toufigh Gordi, PhD

https://tgordi.wordpress.com/2016/05

Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Simulation in Drug Development. Toufigh Gordi, PhD. PK/PD modeling and simulation in drug development. Expansion of the body weight model. May 30, 2016. May 30, 2016. Toufigh Gordi, PhD. How would a weight loss model look like? May 26, 2016. June 1, 2016. Toufigh Gordi, PhD. As you may guess, activities on the top increase the BW while those in the bottom decrease it. The scenario in front of us is that our subject feels he is overweight and de...

pharmacometricsonline.blogspot.com pharmacometricsonline.blogspot.com

Pharmacometrics Online: Disease progression Models

http://pharmacometricsonline.blogspot.com/2008/12/disease-progression-models.html

Monday, December 29, 2008. 1  Clinical Pharmacology= Disease progress drug action. 2 PK/PD  Models:. Drug disposition in individuals&populations. Disease state effects (renal&hepatic dysfunction). Pharmacodynamc (dose or concentration, effect). Clinical effects and endpoints. 3 Disease Progression Model. Quatitative model that accounts for the time course of disease status, S(t):. Symptoms - measuer of how a patient feels for functions (clinical end points). 4Motivations for Disease Progression Models.

pharmacometricsonline.blogspot.com pharmacometricsonline.blogspot.com

Pharmacometrics Online: Welcome

http://pharmacometricsonline.blogspot.com/2008/12/welcome.html

Saturday, December 13, 2008. Welcome to this site for learning pharmacometrics. I am new to this area and I thought of using this space to learn about pharmacometrics. From the intial understanding sofar, I have a feel that, this is an exciting area. Particularly when I see the kind of people that are driving this to the next stage. I would greatly appreciate it, if you could participate/contribute with me on this journey to learn. As the famous saying goes :" Stand on the shoulders of giants".

tgordi.wordpress.com tgordi.wordpress.com

July 2015 – Toufigh Gordi, PhD

https://tgordi.wordpress.com/2015/07

Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Simulation in Drug Development. Toufigh Gordi, PhD. PK/PD modeling and simulation in drug development. Reasons to develop mechanistic PK/PD models. July 31, 2015. Toufigh Gordi, PhD. I will go through an example of a semi-mechanistic PK/PD model in my next blog. For those interested, you may take a look at a model we developed for the antimalarial activity of artemisinin:. Brief introduction to PK/PD models. July 30, 2015. Toufigh Gordi, PhD. PK/PD...

tgordi.wordpress.com tgordi.wordpress.com

August 2015 – Toufigh Gordi, PhD

https://tgordi.wordpress.com/2015/08

Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Simulation in Drug Development. Toufigh Gordi, PhD. PK/PD modeling and simulation in drug development. August 26, 2015. Toufigh Gordi, PhD. I am quite hopeful that my newly gained knowledge will be a great tool in communicating with others in the added value of a quantitative approach to increase the efficiency of the process. Some misconceptions about half-life. August 14, 2015. Toufigh Gordi, PhD. What does half-life tell us? August 6, 2015.

tgordi.wordpress.com tgordi.wordpress.com

June 2015 – Toufigh Gordi, PhD

https://tgordi.wordpress.com/2015/06

Pharmacokinetic and Pharmacodynamic (PK/PD) Modeling and Simulation in Drug Development. Toufigh Gordi, PhD. PK/PD modeling and simulation in drug development. Mathematical models in drug development: An overview. June 26, 2015. Toufigh Gordi, PhD. Pharmacokinetic/pharmacodynamics (PK/PD) models: These models correlate the concentration-time profiles of the drug to the time profile of the observed effect. Having a model for the correlation is very helpful in finding the best dosing regimen that provi...

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Inspire Me

Wednesday, January 21, 2009. If you are still checking out my Photog, Thank You! I know this has not been a happening spot lately, but I do intend on getting back into gear. With Baby #2 just around the corner (less than two weeks), I am sure there will be more photos to share. I will also be updating the blog's look and all that fun stuff. Stay tuned also for a contest or two. Spring is almost here.are you ready for memories? Monday, November 17, 2008. Monday, November 3, 2008. Tuesday, October 28, 2008.

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PK/PD

A blog with random discussions on pharmacokinetics, pharmacodynamics and drug development. Try Amazon Prime 30-Day Free Trial. Friday, December 22, 2017. FDA Commissioner Scott Gottlieb on Quantitative Methods in Drug Development. Watch Gottlieb's speech where he outlines the steps FDA is taking to modernize how clinical information to make decisions about the safety/effectiveness of new drugs is being collected and evaluated. In particular he focuses on two aspects -. Here is the transcript. Benefits of...

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Tel 31 (0) 6-20494699. Hartelijk welkom op onze website. PK-Performance is toonaangevend leverancier en bouwer van krachtige motoren. In eigen huis worden de meest bijzondere motoren gebouwd, die veelal voor sportieve doeleinden worden ingezet. Alt="001.jpg" target=" blank". Alt="002.jpg" target=" blank". Alt="003.jpg" target=" blank". Alt="004.jpg" target=" blank". Alt="005.jpg" target=" blank". Alt="006.jpg" target=" blank". Alt="007.jpg" target=" blank". The homepage is created with EEtext.

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PK Personal Korrekt GmbH - Ihr Personaldienstleister! - PK Personal Korrekt GmbH

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