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Welcome to PREDICT Consortium. NA Interference to E. PREDICT will define the next generation of predictive biomarkers through the integration of clinical trial design with functional cancer genomics to enable personalised medicine and the cost-effective delivery of beneficial cancer therapeutics. Clinical samples collected (March 2015). Gene expression microarray data have been deposited in the Gene Expression Omnibus (GEO) archive under accession GSE53000. Latest News and Events. PREDICT has initiated a...

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Welcome to PREDICT Consortium. NA Interference to E. PREDICT will define the next generation of predictive biomarkers through the integration of clinical trial design with functional cancer genomics to enable personalised medicine and the cost-effective delivery of beneficial cancer therapeutics. Clinical samples collected (March 2015). Gene expression microarray data have been deposited in the Gene Expression Omnibus (GEO) archive under accession GSE53000. Latest News and Events. PREDICT has initiated a...
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6 predigo
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Home - PREDICT Consortium - PREDICT Consortium | predictconsortium.eu Reviews

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Welcome to PREDICT Consortium. NA Interference to E. PREDICT will define the next generation of predictive biomarkers through the integration of clinical trial design with functional cancer genomics to enable personalised medicine and the cost-effective delivery of beneficial cancer therapeutics. Clinical samples collected (March 2015). Gene expression microarray data have been deposited in the Gene Expression Omnibus (GEO) archive under accession GSE53000. Latest News and Events. PREDICT has initiated a...

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OCELOT - PREDICT Consortium - PREDICT Consortium

http://www.predictconsortium.eu/bioinformatics/ocelot

Although OCELOT is general enough to work with data from any source, we have focused in particular on renal cancer to develop OCELOT-Renal. A realization of OCELOT with data sets chosen for their relevance to PREDICT research and to renal cancer research in general. OCELOT-Renal can be accessed here: www.cbs.dtu.dk/services/ocelot-1.0/renal/. Site developed by Dare to Think. 169; 2016 PREDICT Consortium.

2

Conference talks given - PREDICT Consortium - PREDICT Consortium

http://www.predictconsortium.eu/conference-talks-given

ESMO/IMPAKT PLENARY KEYNOTE LECTURE: Intratumour heterogeneity: A Challenge for Personalised Medicine. AACR Invited Speaker Intratumour heterogeneity: A Challenge for Personalised Medicine. AACR invited Speaker EU Framework 7 Consortium: Biomarker Discovery in Cancer Research. Invited Visiting Professor at Cedars Sinai Hospital. Invited speaker British Thoracic Oncology Group Intratumour Heterogeneity and Drug Resistance. NCRI Liverpool Intratumour heterogeneity and drug resistance. Renal Cancer 2013 inv...

3

PrediGO - PREDICT Consortium - PREDICT Consortium

http://www.predictconsortium.eu/bioinformatics/predigo

It is likely that the complex repertoire of somatic and germ-line genomic anomalies complement each other and what amounts to a driver event depends on the constellation of passenger events that are also present in the cancer genome. The purpose of PrediGO is to help to resolve the network of these anomalies by identifying biological process level abnormalities in individual cancers based on combined analysis of gene expression, DNA copy number and mutation profiling results. Submit Comment ».

4

Bioinformatics - PREDICT Consortium - PREDICT Consortium

http://www.predictconsortium.eu/bioinformatics

Based on the clinical and molecular evidence reviewed above, we hypothesize that resistance of RCCs to sunitinib and everolimus might occur through one or a combination of the mechanisms (table 1). PREDICT consortium’s functional genomics RNA interference approaches will be applied to identify genes contributing to these resistance mechanisms. Potential mechanisms of sunitinib resistance:. Potential mechanisms of everolimus resistance:. Hypoxia resistance of RCC cells. Hypoxia resistance of RCC cells.

5

Sequenza - PREDICT Consortium - PREDICT Consortium

http://www.predictconsortium.eu/bioinformatics/sequenza

Exome sequencing of tumor specimens is an important component of the PREDICT Consortium’s quest to identify determinants of drug response in renal cancer. Sequenza is a state-of-the-art software to determine tumor copy number profiles directly from matched tumor/normal exome sequencing data. To the best of our knowledge, it is the only software to produce allele-specific copy number profiles from exome sequencing in a manner that accounts for and models tumor ploidy and cellularity. Submit Comment ».

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Skip to the navigation. Skip to the content. You are here: home. Using systems medicine to deliver personalised medicine for colorectal cancer. Histopathologic and Mechanistic Assessment of Angiogenesis Inhibitor Related Toxicities: An EU FP7 Industry-Academia Partnerships and Pathways (IAPP) Funded Project. A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 with cMET inhibitor PF-02341066 in KRAS. WT (with aberrant c-MET) Colorectal Cancer Patients. 160;    research funded by.

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Welcome to PREDICT Consortium. NA Interference to E. PREDICT will define the next generation of predictive biomarkers through the integration of clinical trial design with functional cancer genomics to enable personalised medicine and the cost-effective delivery of beneficial cancer therapeutics. Clinical samples collected (March 2015). Gene expression microarray data have been deposited in the Gene Expression Omnibus (GEO) archive under accession GSE53000. Latest News and Events. PREDICT has initiated a...

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