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Principia Biopharma

Principia Biopharma Inc., a private, clinical-stage company, has created a revolutionary new way to design and develop oral small molecule therapies that are more potent, selective, durable and safer than currently available drugs.

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CONTACTS AT PRINCIPIABIO.COM

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Principia Biopharma | principiabio.com Reviews
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Principia Biopharma Inc., a private, clinical-stage company, has created a revolutionary new way to design and develop oral small molecule therapies that are more potent, selective, durable and safer than currently available drugs.
<META>
KEYWORDS
1 research
2 preclinical
3 phase 1
4 phase 2
5 immunoproteasome inhibitor
6 autoimmune / inflamm
7 hellip;
8 pipeline
9 tailored covalency
10 patients
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research,preclinical,phase 1,phase 2,immunoproteasome inhibitor,autoimmune / inflamm,hellip;,pipeline,tailored covalency,patients,news,careers,leadership,board of directors,investors,diversity and inclusion,scientific publications,news room,terms of use
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Principia Biopharma | principiabio.com Reviews

https://principiabio.com

Principia Biopharma Inc., a private, clinical-stage company, has created a revolutionary new way to design and develop oral small molecule therapies that are more potent, selective, durable and safer than currently available drugs.

INTERNAL PAGES

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1

Board of Directors for Principia Biopharma

http://www.principiabio.com/about/board-of-directors

Srinivas Akkaraju, M.D., Ph.D. Chief Executive Officer, Principia Biopharma. BIO Emerging Companies Section Governing Board. He holds a Swiss Federal Diploma in Pharmacy from the Federal Institute of Technology in Zurich. Mr. Babler also graduated from the Executive Development Program at the Kellogg Graduate School of Management at Northwestern University. Mike Dybbs, Ph.D. Partner, New Leaf Venture Partners. Simeon George, M.D., M.B.A. Partner, SR One. David Kabakoff, Ph.D. Lewis J. Shuster.

2

PRN1008 | rheumatoid arthritis | Principia Biopharma

http://www.principiabio.com/patients

Principia Biopharma is developing PRN1008, an investigational drug in Phase 2 development for pemphigus vulgaris. PRN1371, is a selective, oral, covalent fibroblast growth factor receptor (FGFR) 1-4 inhibitor that is being evaluated in a Phase 1 trial in various solid tumors. Please check back again for updates on future clinical trials. Hane Chow, Inc.

3

Tailored Covalency® | Principia Biopharma

http://www.principiabio.com/tailored-covalency

Powered by Tailored Covalency. Principia Biopharma challenges traditional drug discovery by utilizing its proprietary Tailored Covalency technology to discover new medicines that combine the dosing convenience of an oral small molecule drug with the specificity of an antibody. Benefit of covalent inhibitors. Long effect – short exposure:. Long lasting efficacy without the need to continuously expose the body to circulating drug. Additional benefits of making covalent inhibitors reversible. The synergy of...

4

Pipeline for Principia Biopharma | autoimmune disease | inflammatory disease | cancer

http://www.principiabio.com/pipeline

BTK inhibitor / Pemphigus Vulgaris. BTK inhibitor / Second Indication. FGFR inhibitor / multiple cancers. IO / Solid tumors. Hane Chow, Inc.

5

BTK Inhibitor | autoimmune diseases | Principia Biopharma

http://www.principiabio.com/pipeline/btk-inhibitor

Highly differentiated, first in class opportunity in autoimmune diseases. PRN1008 is an investigational, oral small molecule therapy with the potential to revolutionize the treatment of a wide range of autoimmune and inflammatory diseases, including pemphigus vulgaris, rheumatoid arthritis, systemic lupus erythematosus (SLE), vasculitis, skin diseases, and cancer. PRN1008 was designed utilizing Principia’s Tailored Covalency. Hane Chow, Inc.

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Funding Roundup: Placester, APX Labs, Principia BioPharma, Tubular Labs, ProNai Therapeutics, Everplans, Carmudi, Yik Yak, Codasip, Xappmedia, Electric Cloud, Blucora | VC Trends

http://www.vctrends.com/2014/04/23/funding-roundup-placester-apx-labs-principia-biopharma-tubular-labs-pronai-therapeutics-everplans-carmudi-yik-yak-codasip-xappmedia-electric-cloud-blucora

Read the Latest Technology and Startup News. 47; Funding Roundup: Placester, APX Labs, Principia BioPharma, Tubular Labs, ProNai Therapeutics, Everplans, Carmudi, Yik Yak, Codasip, Xappmedia, Electric Cloud, Blucora. Funding Roundup: Placester, APX Labs, Principia BioPharma, Tubular Labs, ProNai Therapeutics, Everplans, Carmudi, Yik Yak, Codasip, Xappmedia, Electric Cloud, Blucora. Real estate marketing platform and Techstars Boston grad Placester. Mountain View video marketing company Tubular Labs.

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Principia Biopharma

A PIPELINE OF HIGHLY SELECTIVE DRUG CANDIDATES. BTK inhibitor / Pemphigus. BTK inhibitor / ITP. FGFR inhibitor / Solid Tumors. BTK inhibitor / Multiple Sclerosis. The advantage of Tailored Covalency. Traditional oral small molecule drugs are convenient, but often have side effects because they may not be selective. Injectable antibody drugs are highly specific therapies, but an injection is not convenient for the patient. Hellip;the best of both worlds. Hane Chow, Inc.

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