PROSILICO.COM

Prosilico | Leader in ADME/PK-predictions

Models, Packages and Services. New, unique ADME/PK-prediction methods for humans and animals. For drug candidates, competitor drugs and metabolites. Direct from molecular structure to in-vivo. Dose and exposure predictions. Expert advice/supervision and decision support. Optimization of ADME/PK-program/study design. Explanation of unexpected results and poor predictions. Standard, exclusive and customized prediction packages. The benefits of PROSILICO. Improved quality and knowledge. Incl compounds with ...

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Urban Fagerholm

Urban Fagerholm

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Urban Fagerholm

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Urban Fagerholm

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Prosilico | Leader in ADME/PK-predictions | prosilico.com Reviews

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Models, Packages and Services. New, unique ADME/PK-prediction methods for humans and animals. For drug candidates, competitor drugs and metabolites. Direct from molecular structure to in-vivo. Dose and exposure predictions. Expert advice/supervision and decision support. Optimization of ADME/PK-program/study design. Explanation of unexpected results and poor predictions. Standard, exclusive and customized prediction packages. The benefits of PROSILICO. Improved quality and knowledge. Incl compounds with ...

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1 models and services

2 customers and partners

3 assignments

4 news

5 publications

6 about us

7 follow us

8 customers and collaborators

9 news and press

10 selected publications

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Prosilico | Leader in ADME/PK-predictions | prosilico.com Reviews

https://prosilico.com

Models, Packages and Services. New, unique ADME/PK-prediction methods for humans and animals. For drug candidates, competitor drugs and metabolites. Direct from molecular structure to in-vivo. Dose and exposure predictions. Expert advice/supervision and decision support. Optimization of ADME/PK-program/study design. Explanation of unexpected results and poor predictions. Standard, exclusive and customized prediction packages. The benefits of PROSILICO. Improved quality and knowledge. Incl compounds with ...

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prosilico.com

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Selected Publications | Prosilico

http://prosilico.com/press-and-articles

Fagerholm U, Johansson M, Lennernäs H. Comparison between permeability coefficients in rat and human jejunum. Pharmaceutical Research 13(9):1336-42, 1996. Fagerholm U, Lindahl A, Lennernäs H. Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms. Journal of Pharmacy and Pharmacology 49(7):687-90, 1997. Fagerholm U, Nilsson D, Knutson L, Lennernäs H. Jejunal permeability in humans. International Journal of Pharmaceutics 127:103-7, 1995.

2

News and Press | Prosilico

http://prosilico.com/news-and-press-2

Signed significant long-term deal with major international pharma company Prosilico to deliver 20000 key human ADME/PK-estimates. 160608) Speaker at BIO Hanse meeting in Stockholm. 160520) Delivered 800 parameter estimates to customer. 160503) Signed an international subscription contract. 160404-6) Attended BIO-Europe in Stockholm. 160330) Speaker at New Updates in Drug Formulations and Bioavailability March 30 in Copenhagen. 160211) Delivered ocular permeability results to customer. 151119) Predicted 1...

3

Models | Prosilico

http://prosilico.com/methods-service

To date PROSILICO has developed and validated 145 models for human and animal ADME/PK, exposures, DDIs and doses and an integrated platform for. The process: Customers send molecular structures (SMILES) to PROSILICO, who predict ADME/PK-estimates using various. For more information and pricing, contact Urban Fagerholm (urban.fagerholm@prosilico.com).

4

About us | Prosilico

http://prosilico.com/about-us

PROSILICO is run by Urban Fagerholm (CEO, associate professor and model developer) and Sven Hellberg (PhD and Head of data analysis). PROSILICO was founded in July 2014 by ex-AstraZeneca pharmacokineticist, PhD and associate professor in biopharmaceutics/pharmacokinetics Urban Fagerholm. In 2009, he was nominated International Educator of the Year and named member of Top 100 Professionals of the Year. ADME/PK). He also evaluated, improved and developed several ADME/PK prediction methods and platforms...

5

Customers and Collaborators | Prosilico

http://prosilico.com/customers-and-collaborators

Currently, PROSILICO serves 19 customers, including one big pharma company. Among them are. 8211; Red Glead Discovery. 8211; Forendo Pharma. Finland (http:/ forendo.com/). 8211; Noviga Research. 8211; Umecrine Cognition. 8211; Quretech Bio. Read about our collaboration here (http:/ blog.chemnotia.com/). Virtual design of drug and drug candidate analogues with superior properties. Collaborates with University of Eastern Finland around prodrug-predictons. 8220;Y our efforts. 8211; “Impressed!

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Prosilico | Leader in ADME/PK-predictions

Models, Packages and Services. New, unique ADME/PK-prediction methods for humans and animals. For drug candidates, competitor drugs and metabolites. Direct from molecular structure to in-vivo. Dose and exposure predictions. Expert advice/supervision and decision support. Optimization of ADME/PK-program/study design. Explanation of unexpected results and poor predictions. Standard, exclusive and customized prediction packages. The benefits of PROSILICO. Improved quality and knowledge. Incl compounds with ...

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