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Developing targeted therapeutics for genetically linked diseases. Finding solutions for Parkinson’s today. Power through innovative solvent mapping tools. Our Research – Leveraging Computational Technologies. Proteus uses computational tools and molecular modeling techniques to identify pre-clinical drug candidates that have therapeutic impact and selectivity. Recent Insights — Parkinson’s Disease and LRRK2. Scientific Inquiries — Collaboration and Partnering. Proteus Discovery, Inc.

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Developing targeted therapeutics for genetically linked diseases. Finding solutions for Parkinson’s today. Power through innovative solvent mapping tools. Our Research – Leveraging Computational Technologies. Proteus uses computational tools and molecular modeling techniques to identify pre-clinical drug candidates that have therapeutic impact and selectivity. Recent Insights — Parkinson’s Disease and LRRK2. Scientific Inquiries — Collaboration and Partnering. Proteus Discovery, Inc.
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https://qa.proteusdiscovery.com

Developing targeted therapeutics for genetically linked diseases. Finding solutions for Parkinson’s today. Power through innovative solvent mapping tools. Our Research – Leveraging Computational Technologies. Proteus uses computational tools and molecular modeling techniques to identify pre-clinical drug candidates that have therapeutic impact and selectivity. Recent Insights — Parkinson’s Disease and LRRK2. Scientific Inquiries — Collaboration and Partnering. Proteus Discovery, Inc.

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| Parkinson’s Disease and LRRK2

http://qa.proteusdiscovery.com/parkinsons-disease-and-lrrk2

Parkinson’s Disease and LRRK2. Parkinson’s disease (PD) is a debilitating brain disorder that occurs when dopaminergic neurons in the brain become impaired, leading to impaired coordination, tremors, muscle rigidity, and eventually cognitive deterioration. While PD is traditionally considered a non-genetic disorder, recent studies have show that leucine-rich repeat kinase 2 (LRRK2) protein is directly linked to the disease. For more information on our PD initiative and other targets, see our Pipeline.

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| About Us

http://qa.proteusdiscovery.com/about-us

The Proteus management team is comprised of experienced business and technical leaders who are pushing the limits of current research. Our researchers have a diverse mix of skills across computational chemistry, molecular modelling and experimental science. The core members include:. Is founder and CEO of Proteus. He is an experienced biotechnology entrepreneur and patent attorney with a technical background in computational sciences and bioinformatics. He is a founder of Agrivida (agricultural b...

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| Collaboration and Partnering

http://qa.proteusdiscovery.com/collaboration-and-partnering

Proteus has formed strategic alliances with a number of academic and corporate partners who share our vision. These partnerships leverage new insights into genetically linked diseases to deliver breakthrough treatments for patients with neurodegenerative diseases, cancer, inflammatory/immunologic disorders and other diseases. If you would like more information about partnering opportunities, please contact us. Using innovative tools to gain insight into some of the most challenging diseases.

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| Our Approach

http://qa.proteusdiscovery.com/our-approach

MM-GB/SA and Free Energy Perturbation. Our key advantage is the tight integration between the accurate high-throughput computational tools, rapid iterations of experimental feedback, and an expert team of scientists who have established track records in both computational and experimental drug discovery efforts. Some of those core technologies are listed below. MM-GB/SA and Free Energy Perturbation. Proteus leverages skills in high-performance computing, molecular simulation, and structure-based drug des...

5

| News

http://qa.proteusdiscovery.com/news

Dr Soumya Ray Delivers Opening Lecture. April 20, 2012. Dr Soumya Ray delivered the opening lecture at Schrodinger’s Regional User Meeting in San Francisco, titled: Application of metadynamics simulations in protein biochemistry and drug discovery . See the full schedule here. Comments Off on Dr. Soumya Ray Delivers Opening Lecture. Continue Reading →. Using innovative tools to gain insight into some of the most challenging diseases. Proteus Discovery, Inc. Cambridge, MA 02139-4102.

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Developing targeted therapeutics for genetically linked diseases. Finding solutions for Parkinson’s today. Power through innovative solvent mapping tools. Our Research – Leveraging Computational Technologies. Proteus uses computational tools and molecular modeling techniques to identify pre-clinical drug candidates that have therapeutic impact and selectivity. Recent Insights — Parkinson’s Disease and LRRK2. Scientific Inquiries — Collaboration and Partnering. Proteus Discovery, Inc.

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