REISENAUERGEN564S16.WEEBLY.COM
HomeThis web page was produced as an assignment for Genetics 564 , an undergraduate capstone course at UW-Madison .
http://reisenauergen564s16.weebly.com/
This web page was produced as an assignment for Genetics 564 , an undergraduate capstone course at UW-Madison .
http://reisenauergen564s16.weebly.com/
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Home | reisenauergen564s16.weebly.com Reviews
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This web page was produced as an assignment for Genetics 564 , an undergraduate capstone course at UW-Madison .
reisenauergen564s16.weebly.com
Domains / Motifs
http://reisenauergen564s16.weebly.com/domains--motifs.html
Protein Domains and Motifs. Proteins are all part of families: evolutionarily conserved groups of proteins that share function, structure, or sequence [1]. Protein domains, as shown above for SURF1, are distinct structural or functional sections of a sequence. SURF1 only has one domain, which is involved in transmembrane protein function. Image generated from a combination of SMART and PFAM databases [2]. Three protein motifs were identified with conservation across all model organisms analyzed [. It's i...
Protein
http://reisenauergen564s16.weebly.com/protein.html
Accession: NP 003163.1. SURF1 sequences in different organisms and sequence alignments. SURF1 conservation across various model organisms and phylogenetic trees. Protein domains and motifs. SURF1 protein domains and motifs that predict function. Above are the protein sequences for several SURF1 homologs. This plain-text document is used to generate phylogenetic trees and the sequences are acquired from the homolog's FASTA (see Protein Homology page). Create a free website.
Interaction Network
http://reisenauergen564s16.weebly.com/interaction-network.html
What is a protein interaction? Protein interaction networks are graphical ways of representing protein-protein interactions. These interactions are deduced from experimental data and inferred from theoretical data, and can be direct or indirect interactions. These diagrams can give clues as to the function of the protein of interest. For example, if the protein interacts with. Then that protein is probably involved in that process. The diagram above furthers understanding of the extensive role SURF1 play...
Gene
http://reisenauergen564s16.weebly.com/gene.html
Length : 4681 bp. SURF1 sequences in different organisms and sequence alignments. SURF1 conservation across various model organisms and phylogenetic trees. SURF1 plays in the cell and organism as a whole. RNAi and mutant phenotypes of SURF1. Create a free website.
Modifications
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Why is it important to understand protein modifications? The proteome is a complex, ever-changing series of gene expressions. The proteome is unique in every individual and can even vary given the stressors and demands of the system at any moment in time [2]. Biosignatures and biomarkers responsible for the diagnosis, prognosis and therapeutic prediction [3]. Overview of Post-Translational Modifications (PTMs)", ThermoFisher Scientific. Proteo Consult, 2004. What is Cancer Proteomics?
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Projects - Genetics 564
http://genetics564.weebly.com/projects.html
Spring 2016 Student Projects. Matthew Busalacchi: Familial Melanoma and Pigmentation (MC1R). Salvador Carranza: Cystinosis (CTNS). Mikayla Gallenberger: Acute Lymphoblastic Leukemia (PAX5). Sara Grange: Synesthesia (KIAA0319). Aidan Holmes: Wilson Disease (ATP7B). Bailey Marquardt: Developmental Dyslexia (ROBO1). Troy Meikle: Autoimmune lymphoproliferative syndrome (FAS). Mary Mohr: Cardiovascular Disease in Women (BCAR1/p130CAS). Kathryn Ness: CHARGE Syndrome (CHD7). Tia Ramirez: FOXG1 Syndrome (FOXG1).
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A study of mitochondria-driven neurodegeneration. This web page was produced as an assignment for Genetics 564. An undergraduate capstone course at UW-Madison. Leigh Syndrome (LS) identifies under several pen names, but it is known for it's presentation during infancy between three months and two years old as degeneration of the central nervous system and failure to thrive. Approximately 1 in 40,000 newborns will be affected by LS [3]. Oxidase or COX) have been found in upwards of 70% of cases [1]. Leigh...
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