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Clinical Trial Site Log-In. AM I A CANDIDATE? Have you been told by your doctor that you have heart failure? Are you taking medications for your heart failure? Are symptoms - such as shortness of breath, fatigue, or swelling - limiting your ability to do everyday activities and affecting your quality of life? If you answered "YES". To learn more about this investigational therapy and the trial, click on the buttons at the bottom of this website. What is Heart Failure? What is CRT Optimization?

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Clinical Trial Site Log-In. AM I A CANDIDATE? Have you been told by your doctor that you have heart failure? Are you taking medications for your heart failure? Are symptoms - such as shortness of breath, fatigue, or swelling - limiting your ability to do everyday activities and affecting your quality of life? If you answered YES. To learn more about this investigational therapy and the trial, click on the buttons at the bottom of this website. What is Heart Failure? What is CRT Optimization?
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Clinical Trial Site Log-In. AM I A CANDIDATE? Have you been told by your doctor that you have heart failure? Are you taking medications for your heart failure? Are symptoms - such as shortness of breath, fatigue, or swelling - limiting your ability to do everyday activities and affecting your quality of life? If you answered "YES". To learn more about this investigational therapy and the trial, click on the buttons at the bottom of this website. What is Heart Failure? What is CRT Optimization?

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What is SonR-

http://www.respondcrt.com/public-navigation/what-is-sonr-

Clinical Trial Site Log-In. Sorin Method to Optimize CRT. Your doctor has recommended that you receive the Sorin Paradym RF SonR CRT device and the SonRtip lead. The Paradym RF SonR CRT device has special software that automatically measures your heart function. The information can then be used to optimize CRT. The SonRtip lead wire, which is placed in the right upper chamber of the heart, contains a special sensor that measures the strength of heart contractions. What is Heart Failure?

2

Publications

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Clinical Trial Site Log-In. References for the Benefits of CRT. 1 Young JB, Abraham WT, Smith AI, Leon AR, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: The MIRACLE-ICD Trial. JAMA 2003;289:2685-2694. Stay out of the hospital. 1 Bristow MR, Saxon LA., Boehmer J, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med 2004;350:2140-2150. 1 Abraham WT, Fi...

3

What is CRT-

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Clinical Trial Site Log-In. In some people with heart failure, the heart doesn't beat in a smooth and coordinated way. Cardiac resynchronization therapy or CRT may help your heart beat more efficiently and pump blood better. CRT is delivered with a small implantable device that is connected to your heart with three thin lead wires. Not everyone responds to CRT in the same way. What is a CRT Device? What Happens during a Typical CRT Implant Procedure? Approximately 1-2 hour procedure. Heart failure pacing...

4

Locations

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Clinical Trial Site Log-In. Participating RESPOND CRT Clinical Trial Sites in the United States. Please check back soon to learn more about which institutions near you may be participating in this important study. For more information please visit. Brookwood Medical Center - CV Associates of the SE. Dr Russel Reeves, M.D. Brotman Medical Center - CV Medical Group of S. California. Dr Eli Gang, M.D. Hoag Memorial Hospital Presbyterian. Dr Brian Che snie. Scripps Health d/b/a - Scripps Mercy Hospital.

5

What is CRT Optimization-

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WHAT IS CRT OPTIMIZATION? Clinical Trial Site Log-In. Doctors have tried to improve patients’ response to CRT. One method is to fine tune or “optimize” the settings on the heart failure device. The fine tuning process usually involves measuring heart activity with an echocardiogram - ultrasound picture of the heart - and then using the information to reprogram the device. CRT optimization can take a lot of time. Also, the settings that work best for you may change over time. What is Heart Failure?

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Clinical Trial Site Log-In. AM I A CANDIDATE? Have you been told by your doctor that you have heart failure? Are you taking medications for your heart failure? Are symptoms - such as shortness of breath, fatigue, or swelling - limiting your ability to do everyday activities and affecting your quality of life? If you answered "YES". To learn more about this investigational therapy and the trial, click on the buttons at the bottom of this website. What is Heart Failure? What is CRT Optimization?

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